ofloxacin has been researched along with Meningitis, Meningococcal in 3 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Meningitis, Meningococcal: A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Organisms from Neisseria meningitidis serogroups A, B, C, Y, and W-135 have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ofloxacin diffusion into cerebrospinal fluid (CSF) was evaluated in nine patients with bacterial meningitis." | 7.67 | Diffusion of ofloxacin into the cerebrospinal fluid in patients with bacterial meningitis. ( Bru, JP; Croize, J; Fourtillan, JB; Guyot, A; Leduc, D; Lefèbvre, MA; Micoud, M; Stahl, JP, 1986) |
| "Ofloxacin diffusion into cerebrospinal fluid (CSF) was evaluated in nine patients with bacterial meningitis." | 3.67 | Diffusion of ofloxacin into the cerebrospinal fluid in patients with bacterial meningitis. ( Bru, JP; Croize, J; Fourtillan, JB; Guyot, A; Leduc, D; Lefèbvre, MA; Micoud, M; Stahl, JP, 1986) |
| "We have assessed levofloxacin penetration in cerebrospinal fluid (CSF) and the liquor-to-plasma ratio (C(L)/C(P)) at 2 hours after dosing in 5 patients with spontaneous acute bacterial meningitis." | 1.31 | Cerebrospinal fluid penetration of levofloxacin in patients with spontaneous acute bacterial meningitis. ( Baraldo, M; Furlanut, M; Giobbia, M; Pea, F; Scotton, PG; Vaglia, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scotton, PG | 1 |
| Pea, F | 1 |
| Giobbia, M | 1 |
| Baraldo, M | 1 |
| Vaglia, A | 1 |
| Furlanut, M | 1 |
| Wada, K | 1 |
| Muramatsu, Y | 1 |
| Tasaki, K | 1 |
| Satou, T | 1 |
| Ozaki, K | 1 |
| Takano, M | 1 |
| Arakawa, M | 1 |
| Stahl, JP | 1 |
| Croize, J | 1 |
| Lefèbvre, MA | 1 |
| Bru, JP | 1 |
| Guyot, A | 1 |
| Leduc, D | 1 |
| Fourtillan, JB | 1 |
| Micoud, M | 1 |
3 other studies available for ofloxacin and Meningitis, Meningococcal
| Article | Year |
|---|---|
Cerebrospinal fluid penetration of levofloxacin in patients with spontaneous acute bacterial meningitis.
Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Meningitis, E | 2001 |
[An infection route of meningococcal meningitis and eradication of carriers].
Topics: Carrier State; Cefixime; Cefotaxime; Female; Humans; Meningitis, Meningococcal; Middle Aged; Ofloxac | 1988 |
Diffusion of ofloxacin into the cerebrospinal fluid in patients with bacterial meningitis.
Topics: Adult; Anti-Infective Agents; Bacterial Infections; Female; Humans; Male; Meningitis; Meningitis, Me | 1986 |