Page last updated: 2024-11-01

ofloxacin and Malaria, Falciparum

ofloxacin has been researched along with Malaria, Falciparum in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, ME1
Parrott, EE1
Singh, R1
Nelson, SW1
Hobeika, EM1
Usta, IM1
Taher, AT1
Nassar, AH1

Reviews

1 review available for ofloxacin and Malaria, Falciparum

ArticleYear
Splenomegaly, pancytopenia and pregnancy: a case report and review of the literature.
    The Journal of infection, 2005, Volume: 51, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Blood Transfusion; Diagnostic Errors; Female; Glucocorticoids; Hepatom

2005

Other Studies

1 other study available for ofloxacin and Malaria, Falciparum

ArticleYear
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
    Journal of biomolecular screening, 2014, Volume: 19, Issue:6

    Topics: Antimalarials; Apicoplasts; Chloroplasts; DNA; DNA-Directed DNA Polymerase; Drug Discovery; Exonucle

2014