ofloxacin has been researched along with Lymphoma in 12 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed population pharmacokinetic analysis for seven patients receiving LVFX as prophylaxis (200 mg, b." | 6.73 | Population pharmacokinetics of levofloxacin as prophylaxis for febrile neutropenia. ( Fujimoto, Y; Kanbayashi, Y; Matsumoto, Y; Morimoto, Y; Nomura, K; Taniwaki, M, 2008) |
| "Levofloxacin may be effective for treatment of rectal lymphoma of mucosa-associated lymphoid tissue regardless of Helicobacter pylori infection." | 5.32 | Regression of rectal mucosa-associated lymphoid tissue lymphoma but persistence of Helicobacter pylori infection of gastric mucosa after administration of levofloxacin: report of a case. ( Dohden, K; Hattori, M; Hayashi, H; Hosokawa, O; Kaizaki, Y, 2004) |
| "Bacteremia was documented in two patients in the O+R group and six in the control group (p=0." | 5.30 | Intensified prophylaxis of febrile neutropenia with ofloxacin plus rifampin during severe short-duration neutropenia in patients with lymphoma. ( Brunet, S; Martino, R; Muñoz, L; Sierra, J; Subirà, M; Sureda, A, 1999) |
| "These findings suggest that, despite increasing rates of antimicrobial resistance, levofloxacin prophylaxis during neutropenia may have a beneficial impact on morbidity and infection-related mortality." | 5.11 | Impact of fluoroquinolone prophylaxis on reduced infection-related mortality among patients with neutropenia and hematologic malignancies. ( Döhner, H; Kern, P; Kern, WV; Marre, R; Reuter, S; Sigge, A; von Baum, H, 2005) |
| "We evaluated the effectiveness of ofloxacin (OFX) administered for prophylactic purposes during 77 episodes of neutropenia (less than 500/mm3) in 54 patients with hematological malignancies and to combat infection in 17 patients with both hematological malignancies and secondary infections." | 5.07 | Use of ofloxacin in prevention and treatment of secondary infections in hematological malignancies. ( Okuma, M; Sawada, H; Tashima, M, 1991) |
| "We performed population pharmacokinetic analysis for seven patients receiving LVFX as prophylaxis (200 mg, b." | 2.73 | Population pharmacokinetics of levofloxacin as prophylaxis for febrile neutropenia. ( Fujimoto, Y; Kanbayashi, Y; Matsumoto, Y; Morimoto, Y; Nomura, K; Taniwaki, M, 2008) |
| "Patients who are treated for acute leukemia should be offered prophylaxis with ciprofloxacin or levofloxacin." | 2.43 | Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions. ( Bucaneve, G; Cullen, M; Fraser, A; Gafter-Gvili, A; Kern, WV; Leibovici, L; Paul, M, 2006) |
| "Levofloxacin n-oxide is an impurity isolated from levofloxacin." | 1.38 | In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin. ( Guo, M; Li, J; Li, T; Wang, W; Zhang, X; Zhu, Q, 2012) |
| "Levofloxacin may be effective for treatment of rectal lymphoma of mucosa-associated lymphoid tissue regardless of Helicobacter pylori infection." | 1.32 | Regression of rectal mucosa-associated lymphoid tissue lymphoma but persistence of Helicobacter pylori infection of gastric mucosa after administration of levofloxacin: report of a case. ( Dohden, K; Hattori, M; Hayashi, H; Hosokawa, O; Kaizaki, Y, 2004) |
| "Bacteremia was documented in two patients in the O+R group and six in the control group (p=0." | 1.30 | Intensified prophylaxis of febrile neutropenia with ofloxacin plus rifampin during severe short-duration neutropenia in patients with lymphoma. ( Brunet, S; Martino, R; Muñoz, L; Sierra, J; Subirà, M; Sureda, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Esparza, EM | 1 |
| Takeshita, J | 1 |
| George, E | 1 |
| Zhu, Q | 1 |
| Li, T | 1 |
| Li, J | 1 |
| Guo, M | 1 |
| Wang, W | 1 |
| Zhang, X | 1 |
| Gracia Escudero, A | 1 |
| Martín González, M | 1 |
| Giménez Garrido, F | 1 |
| Clavero Farré, C | 1 |
| García Pérez, MJ | 1 |
| Alvarez Corral, G | 1 |
| Reyes Bertos, A | 1 |
| Villegas Maldonado, G | 1 |
| Rodríguez Cuartero, A | 1 |
| Dohden, K | 1 |
| Kaizaki, Y | 1 |
| Hosokawa, O | 1 |
| Hayashi, H | 1 |
| Hattori, M | 1 |
| Reuter, S | 1 |
| Kern, WV | 2 |
| Sigge, A | 1 |
| Döhner, H | 1 |
| Marre, R | 1 |
| Kern, P | 1 |
| von Baum, H | 1 |
| Castagna, L | 1 |
| Santoro, A | 1 |
| Leibovici, L | 1 |
| Paul, M | 1 |
| Cullen, M | 1 |
| Bucaneve, G | 1 |
| Gafter-Gvili, A | 1 |
| Fraser, A | 1 |
| Nomura, K | 1 |
| Fujimoto, Y | 1 |
| Morimoto, Y | 1 |
| Kanbayashi, Y | 1 |
| Matsumoto, Y | 1 |
| Taniwaki, M | 1 |
| Muñoz, L | 1 |
| Martino, R | 1 |
| Subirà, M | 1 |
| Brunet, S | 1 |
| Sureda, A | 1 |
| Sierra, J | 1 |
| D'Antonio, D | 1 |
| Pizzigallo, E | 1 |
| Iacone, A | 1 |
| Dell'Isola, M | 1 |
| Fioritoni, G | 1 |
| Betti, S | 1 |
| Piergallini, A | 1 |
| Di Gianfilippo, R | 1 |
| Olioso, P | 1 |
| Torlontano, G | 1 |
| Tsutani, H | 1 |
| Imamura, S | 1 |
| Ueda, T | 1 |
| Yoshida, H | 1 |
| Iwasaki, H | 1 |
| Fukushima, T | 1 |
| Yoshimura, T | 1 |
| Toyooka, S | 1 |
| Nakamura, T | 1 |
| Sawada, H | 1 |
| Tashima, M | 1 |
| Okuma, M | 1 |
1 review available for ofloxacin and Lymphoma
| Article | Year |
|---|---|
Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions.
Topics: Acute Disease; Antibiotic Prophylaxis; Antineoplastic Agents; Bone Marrow Transplantation; Ciproflox | 2006 |
5 trials available for ofloxacin and Lymphoma
| Article | Year |
|---|---|
[A prospective, controlled, non-randomized study of three cohorts to test the effectiveness of two antibiotics levofloxacin and cotrimoxazol on antibacterial prophylaxis in neutropenic patients].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Humans; Leukemia; Levofloxac | 2003 |
Impact of fluoroquinolone prophylaxis on reduced infection-related mortality among patients with neutropenia and hematologic malignancies.
Topics: Amyloidosis; Anemia, Aplastic; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; | 2005 |
Population pharmacokinetics of levofloxacin as prophylaxis for febrile neutropenia.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Dose-Response Relationship, Drug; Female | 2008 |
Prophylactic use of ofloxacin in granulocytopenic patients with hematological malignancies during post-remission chemotherapy.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Antineoplastic Agents; Bacterial Infections; Female; Human | 1992 |
Use of ofloxacin in prevention and treatment of secondary infections in hematological malignancies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cause of Death; Female; Humans; Leukemia; Lymphoma; Male | 1991 |
6 other studies available for ofloxacin and Lymphoma
| Article | Year |
|---|---|
Lymphomatoid hypersensitivity reaction to levofloxacin during autologous stem cell transplantation: a potential diagnostic pitfall in patients treated for lymphoma or leukemia.
Topics: Anti-Bacterial Agents; Biomarkers, Tumor; Diagnosis, Differential; Drug Eruptions; Female; Hematopoi | 2011 |
In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin.
Topics: Animals; Cell Line, Tumor; Chi-Square Distribution; Chromosome Aberrations; Computer Simulation; Cri | 2012 |
Regression of rectal mucosa-associated lymphoid tissue lymphoma but persistence of Helicobacter pylori infection of gastric mucosa after administration of levofloxacin: report of a case.
Topics: Anti-Infective Agents; Female; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter py | 2004 |
Antibacterial prophylaxis in patients with cancer and neutropenia.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Fever; Hospitalization; Humans; | 2006 |
Intensified prophylaxis of febrile neutropenia with ofloxacin plus rifampin during severe short-duration neutropenia in patients with lymphoma.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Bact | 1999 |
Occurrence of bacteremia in hematologic patients.
Topics: Adolescent; Adult; Aged; Bacteremia; Bone Marrow Transplantation; Catheterization; Ciprofloxacin; Fe | 1992 |