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ofloxacin and Lupus Erythematosus, Systemic

ofloxacin has been researched along with Lupus Erythematosus, Systemic in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Research Excerpts

ExcerptRelevanceReference
"We describe two patients with systemic lupus erythematosus (SLE) who presented with fever, systemic upset and pulmonary infiltrates between April and June, 2003."1.32Lupus pneumonitis or severe acute respiratory syndrome? ( Mok, CC; Ying, KY, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amankwa, K1
Krishnan, SC1
Tisdale, JE1
Mok, CC1
Ying, KY1

Other Studies

2 other studies available for ofloxacin and Lupus Erythematosus, Systemic

ArticleYear
Torsades de pointes associated with fluoroquinolones: importance of concomitant risk factors.
    Clinical pharmacology and therapeutics, 2004, Volume: 75, Issue:3

    Topics: Aged; Cardiovascular Diseases; Female; Fluoroquinolones; Humans; Levofloxacin; Lupus Erythematosus,

2004
Lupus pneumonitis or severe acute respiratory syndrome?
    Lupus, 2004, Volume: 13, Issue:7

    Topics: Adult; Antiviral Agents; China; Community-Acquired Infections; Diagnosis, Differential; Female; Huma

2004