ofloxacin has been researched along with Liver Failure in 2 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The optimal period of antibiotic treatment of hepatic failure with SBP should be from 7 days to 10 days." | 1.32 | [A prospective study on short period antibiotic treatment of hepatic failure complicated with spontaneous bacterial peritonitis]. ( Du, N; He, WP; Ji, W; Li, HW; Wang, HF; Xia, J; Zhao, P, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, HW | 1 |
| Zhao, P | 1 |
| Wang, HF | 1 |
| Ji, W | 1 |
| He, WP | 1 |
| Du, N | 1 |
| Xia, J | 1 |
| González Carro, P | 1 |
| Huidobro, ML | 1 |
| Zabala, AP | 1 |
| Vicente, EM | 1 |
2 other studies available for ofloxacin and Liver Failure
| Article | Year |
|---|---|
[A prospective study on short period antibiotic treatment of hepatic failure complicated with spontaneous bacterial peritonitis].
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Ceftriaxone; Drug Therapy, Combination; Female; | 2004 |
Fatal subfulminant hepatic failure with ofloxacin.
Topics: Aged; Fatal Outcome; Humans; Liver Failure; Male; Ofloxacin | 2000 |