ofloxacin has been researched along with Liver Cirrhosis, Alcoholic in 3 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Liver Cirrhosis, Alcoholic: FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ofloxacin kinetics were influenced by renal dysfunction encountered in patients with ascites." | 2.38 | Pharmacokinetics of fluoroquinolones in hepatic failure. ( Gaillot, J; Montay, G, 1990) |
| " Mean plasma elimination half-life was 11." | 1.28 | Oral pharmacokinetics and ascitic fluid penetration of ofloxacin in cirrhosis. ( Beauchant, M; Becq-Giraudon, B; Bouquet, S; Breux, JP; Silvain, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bagnato, GF | 1 |
| Di Cesare, E | 1 |
| Gulli, S | 1 |
| Cucinotta, D | 1 |
| Montay, G | 1 |
| Gaillot, J | 1 |
| Silvain, C | 1 |
| Bouquet, S | 1 |
| Breux, JP | 1 |
| Becq-Giraudon, B | 1 |
| Beauchant, M | 1 |
1 review available for ofloxacin and Liver Cirrhosis, Alcoholic
| Article | Year |
|---|---|
Pharmacokinetics of fluoroquinolones in hepatic failure.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Ha | 1990 |
2 other studies available for ofloxacin and Liver Cirrhosis, Alcoholic
| Article | Year |
|---|---|
Long-term treatment of pulmonary tuberculosis with ofloxacin in a subject with liver cirrhosis.
Topics: Administration, Oral; Anti-Infective Agents; Antitubercular Agents; Ethambutol; Follow-Up Studies; H | 1995 |
Oral pharmacokinetics and ascitic fluid penetration of ofloxacin in cirrhosis.
Topics: Administration, Oral; Adult; Ascitic Fluid; Diffusion; Female; Humans; Liver Cirrhosis, Alcoholic; M | 1989 |