Page last updated: 2024-11-01

ofloxacin and Leukemia, Myeloid, Acute

ofloxacin has been researched along with Leukemia, Myeloid, Acute in 5 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schmidt-Hieber, M1
Stroux, A1
Thiel, E1
Blau, IW1
Sajben, P1
Minárik, T1
Tomásik, E1
Mardiak, J1
Danisovicovà, A1
Trupl, T1
Krcméry, V1
Kim, HS1
Min, YD1
Choi, CH1
Mociková, K1
Svác, J1
Faber, E1
Wildová, B1
Baníková, I1
Bartoloni, A1
Fanci, R1
Orsi, A1
Aquilini, D1
Bosi, A1
Rossi Ferrini, P1
Paradisi, F1

Trials

3 trials available for ofloxacin and Leukemia, Myeloid, Acute

ArticleYear
Antibacterial prophylaxis with levofloxacin in patients after allogeneic stem cell transplantation and neutrophil reconstitution: results from a double-blinded, placebo-controlled phase III trial and overview of recent clinical practice.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Double-Blind Method; Female; Humans; Leukemia, Myelo

2010
Fluconazol plus ofloxacin in prophylaxis of infections in patients with acute leukemia: a comparative study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1993, Volume: 1, Issue:4

    Topics: Adult; Bacterial Infections; Drug Costs; Drug Therapy, Combination; Female; Fluconazole; Humans; Inc

1993
The influence of ofloxacin versus trimethoprim-sulfamethoxazole on the aerobic flora in granulocytopenic subjects.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:2

    Topics: Adult; Aged; Agranulocytosis; Bacteria, Aerobic; Drug Combinations; Female; Humans; Intestines; Leuk

1989

Other Studies

2 other studies available for ofloxacin and Leukemia, Myeloid, Acute

ArticleYear
Double-edged sword of chemosensitizer: increase of multidrug resistance protein (MRP) in leukemic cells by an MRP inhibitor probenecid.
    Biochemical and biophysical research communications, 2001, Apr-27, Volume: 283, Issue:1

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette

2001
[Comparison of Tarivid and Biseptol in the prevention of bacterial infections in patients with acute leukemia].
    Vnitrni lekarstvi, 1992, Volume: 38, Issue:2

    Topics: Bacterial Infections; Female; Humans; Leukemia, Myeloid, Acute; Male; Neutropenia; Ofloxacin; Precur

1992