ofloxacin has been researched along with Leptospirosis in 5 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Leptospirosis: Infections with bacteria of the genus LEPTOSPIRA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leptospirosis and scrub typhus are common zoonoses and coinfection with both diseases has been reported sporadically, particularly in tropical and subtropical areas." | 5.38 | Successful treatment of septic shock and respiratory failure due to leptospirosis and scrub typhus coinfection with penicillin, levofloxacin, and activated protein C. ( Chiu, CT; Lai, CH; Lai, YF; Lin, HH; Wei, YF, 2012) |
| "Ofloxacin (30 mg/kg) was unable to clear bacteria from blood or kidneys." | 5.31 | Quantitative PCR assay to evaluate ampicillin, ofloxacin, and doxycycline for treatment of experimental leptospirosis. ( Charavay, F; Merien, F; Perolat, P; Truccolo, J, 2002) |
| "Leptospirosis and scrub typhus are common zoonoses and coinfection with both diseases has been reported sporadically, particularly in tropical and subtropical areas." | 1.38 | Successful treatment of septic shock and respiratory failure due to leptospirosis and scrub typhus coinfection with penicillin, levofloxacin, and activated protein C. ( Chiu, CT; Lai, CH; Lai, YF; Lin, HH; Wei, YF, 2012) |
| "Ofloxacin (30 mg/kg) was unable to clear bacteria from blood or kidneys." | 1.31 | Quantitative PCR assay to evaluate ampicillin, ofloxacin, and doxycycline for treatment of experimental leptospirosis. ( Charavay, F; Merien, F; Perolat, P; Truccolo, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, WS | 1 |
| Ou, TY | 1 |
| Chen, FL | 1 |
| Hsu, CW | 1 |
| Jean, SS | 1 |
| Wei, YF | 1 |
| Chiu, CT | 1 |
| Lai, YF | 1 |
| Lai, CH | 1 |
| Lin, HH | 1 |
| Griffith, ME | 2 |
| Moon, JE | 1 |
| Johnson, EN | 1 |
| Clark, KP | 1 |
| Hawley, JS | 1 |
| Hospenthal, DR | 2 |
| Murray, CK | 2 |
| Ressner, RA | 1 |
| Beckius, ML | 1 |
| Pimentel, G | 1 |
| Miller, RS | 1 |
| Mende, K | 1 |
| Fraser, SL | 1 |
| Galloway, RL | 1 |
| Truccolo, J | 1 |
| Charavay, F | 1 |
| Merien, F | 1 |
| Perolat, P | 1 |
5 other studies available for ofloxacin and Leptospirosis
| Article | Year |
|---|---|
Co-infection with Orientia tsutsugamushi and Mycoplasma pneumoniae in a traveler.
Topics: Humans; Leptospirosis; Levofloxacin; Male; Ofloxacin; Penicillins; Protein C; Respiratory Insufficie | 2015 |
Successful treatment of septic shock and respiratory failure due to leptospirosis and scrub typhus coinfection with penicillin, levofloxacin, and activated protein C.
Topics: Anti-Infective Agents; Antibodies, Bacterial; Humans; Leptospira; Leptospirosis; Levofloxacin; Male; | 2012 |
Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Ciprofloxacin; Cricetinae; Disease Models, Animal; Do | 2007 |
Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira.
Topics: Ampicillin; Anti-Bacterial Agents; Azithromycin; Cefepime; Cefotaxime; Ceftriaxone; Cephalosporins; | 2008 |
Quantitative PCR assay to evaluate ampicillin, ofloxacin, and doxycycline for treatment of experimental leptospirosis.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cricetinae; Doxycycline; Leptospi | 2002 |