ofloxacin has been researched along with Koch's Disease in 79 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (3.80) | 18.7374 |
1990's | 14 (17.72) | 18.2507 |
2000's | 27 (34.18) | 29.6817 |
2010's | 32 (40.51) | 24.3611 |
2020's | 3 (3.80) | 2.80 |
Authors | Studies |
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Balasubramanian, V; Bharath, S; Gaonkar, S; Jayaram, R; Jayashree, R; Kaur, P; Mahesh, BN; Nandi, V; Shandil, RK; Suresh, BL | 1 |
Bocanegra-García, V; García, A; Palma-Nicolás, JP; Rivera, G | 1 |
Devi, PB; Jeankumar, VU; Pedgaonkar, GS; Renuka, J; Saxena, S; Sridevi, JP; Sriram, D; Yogeeswari, P | 2 |
Mahajan, SS; Saharan, VD | 1 |
Cheng, XW; Fan, YL; Feng, LS; Wu, JB; Zhang, FZ | 1 |
Dhawan, S; Girase, PS; Karpoormath, R; Kumar, V; Palkar, MB; Shinde, SR | 1 |
Gao, R; Guo, Y; Shen, X; Tan, G; Wang, H; Wu, X; Wu, Z; Yang, J; Yu, F | 1 |
Draper, HR; Garcia-Prats, AJ; Hesseling, AC; Schaaf, HS; van der Laan, LE; Winckler, JL | 1 |
Bao, L; Luo, T; Mi, Y; Peng, X; Sun, C; Wang, C; Yang, G; Yuan, J; Zhang, C | 1 |
Anupurba, S; Balgam, S; Fakir, NA; Gupta, A; Nema, V; Pal, SK; Pandey, D; Periera, M; Rathod, S; Sekar, G; Sinha, D; Sinha, P; SivaKumar, S; UmaDevi, KR | 1 |
Gardezi, AH; Hussain, A; Ikram, A; Khadim, MT; Satti, L; Zaman, G | 1 |
Ahmad, Z; Grosset, JH; Minkowski, A; Nuermberger, EL; Peloquin, CA; Tyagi, S | 1 |
Bian, A; Blackman, A; Eden, S; Maruri, F; Mitchel, E; Shintani, AK; Sterling, TR; van der Heijden, YF; Warkentin, JV | 1 |
Chang, KC; Dheda, K | 1 |
Aubry, A; Brossier, F; Chauffour, A; Fillion, A; Jarlier, V; Veziris, N | 1 |
Chandrasekaran, V; Dewan, P; Hemanth Kumar, AK; Ramachandran, G; Swaminathan, S; Thomas, A | 1 |
Chen, X; Huang, H; Jiang, GL; Kam, KM; Song, Y; Zhao, Y | 1 |
Blasi, P; Giovagnoli, S; Marenzoni, ML; Nocchetti, M; Ricci, M; Santi, C; Schoubben, A | 1 |
Dixit, P; Jain, A; Jaiswal, I; Prakash, S; Singh, M; Singh, P; Venkatesh, V | 1 |
Alkhovik, OI; Cherednichenko, AG; Dymova, MA; Filipenko, ML; Khrapov, EA; Petrenko, TI | 1 |
Chen, ST; Huang, HR; Jiang, GL; Ma, YF; Wang, GR; Yu, X | 1 |
Blackman, A; Eilertson, B; Guo, Y; Herrera, M; Maruri, F; Shyr, Y; Sterling, TR; van der Heijden, Y | 1 |
Aubry, A; Bernard, C; Brossier, F; Chauffour, A; Robert, J; Veziris, N | 1 |
Chung, SJ; Hwang, SM; Kim, DD; Shim, CK | 1 |
de Gouveia, L; du Plessis, M; Klugman, KP; von Gottberg, A; Wolter, N | 1 |
Chen, YC; Ho, CC; Hu, FC; Luh, KT; Yang, PC; Yu, CJ | 1 |
Bonato, D; Desmond, E; Gross, W; Lin, SY; Siddiqi, S | 1 |
Caminero, JA; Migliori, GB; Sotgiu, G; Zumla, A | 1 |
Aubry, A; Chauffour, A; Farinotti, R; Fernandez, C; Jarlier, V; Lott, MC; Poissy, J; Veziris, N | 1 |
Cui, Z; Hu, Z; Huang, X; Lu, J; Wang, J | 1 |
Cremades, R; Galiana, A; García-Pachón, E; López, P; Rodríguez, JC; Royo, G; Ruiz-García, M | 1 |
Akagawa, S; Ariga, H; Kaneko, Y; Kawabe, Y; Kawashima, M; Kunogi, M; Machida, K; Masuda, K; Matsui, H; Matsui, Y; Nagai, H; Nagayama, N; Nakajima, Y; Ohshima, N; Shimada, M; Suzuki, J; Tamura, A; Toyota, E | 1 |
Aubry, A; Bastian, S; Brossier, F; Jarlier, V; Mayer, C; Pantel, A; Petrella, S; Veziris, N | 1 |
Bugaenko, SE; Elistratova, NA; Maliev, BM; Mozhokina, GN; Sokolova, GB; Solov'eva, IP | 1 |
Du, Q; Fu, Y; Huang, H; Li, W; Liang, Q; Long, Q; Xie, J | 1 |
Dheda, K; Lehloenya, RJ; Todd, G; Wallace, J | 1 |
Keren, I; Lewis, K; Mulcahy, LR | 1 |
Lu, J; Pang, Y; Song, Y; Wang, S; Wang, Y; Zhao, Y | 1 |
Bohle, A; Durek, C; Jocham, D; Jurczok, A; Werner, H | 1 |
Castiñeiras, AA; Della-Latta, P; Herreras, A; Pérez-Pascual, P; Zarranz, JE | 1 |
López, M; Rodríguez, JC; Royo, G; Ruiz, M | 1 |
Aguilar, R; Auclair, B; Maslow, JN; Mikota, SK; Peloquin, CA | 1 |
Benjamin, WH; Bishai, WR; Dorman, SE; Ginsburg, AS; Hooper, N; Sterling, TR; Woolwine, SC | 1 |
Chan, EW; Chan, RC; Cheng, AF; Chin, ML; Hui, MM; Yew, WW | 1 |
Biswas, SK | 1 |
Bhusal, Y; Shiohira, CM; Yamane, N | 1 |
Elwood, RK; FitzGerald, JM; Marra, CA; Marra, F; Moadebi, S; Shi, P; Stark, G | 1 |
Kazumi, Y; Li, C; Shi, R; Sugawara, I; Zhang, J | 1 |
De Souza, MV; Junior, IN; Lourenço, MC | 1 |
Otomo, K; Shi, R; Sugawara, I; Zhang, G; Zhang, J | 1 |
Howell, JM; Mohammadi, A | 1 |
Baggett, P; Gaba, PD; Griffin, MR; Haley, C; Holt, E; Mitchel, E; Sterling, TR; Warkentin, J | 1 |
Grosset, J; JI, B; Lounis, N; Truffot-Pernot, C | 1 |
Li, H; Liu, S; Xu, G | 1 |
Aleksandrova, AE; Vinogradova, TI | 1 |
Bermudez, LE; Kolonoski, P; Young, LS | 1 |
Akaki, T; Kawahara, S; Sato, K; Shimizu, T; Tomioka, H | 1 |
Chirgwin, K; El Sadr, WM; Hafner, R; Heifets, LB; Klein, O; Kreiswirth, BN; Matts, JP; Musser, JM; Nelson, ET; Perlman, DC; Salomon, N; Telzak, EE | 1 |
Padełskaya, EN | 1 |
Akaki, T; Sato, K; Tomioka, H | 1 |
Duan, L; Li, H; Liang, G | 1 |
Fourche, J; Leblanc, F; Maugein, J; Pellegrin, JL; Vacher, S | 1 |
Emre, S; Meyers, BR; Miller, C; Papanicolaou, GA; Sheiner, P | 1 |
Mitchison, D; Sirgel, F; Venter, A | 1 |
Akaki, T; Kawahara, S; Sato, K; Tomioka, H | 1 |
Bowersox, J | 1 |
Duan, L; Lu, Y; Zhu, L | 1 |
Lou, HX; McKaveney, TP; Shullo, MA | 1 |
Domschke, W; Lügering, N; Richter, E; Rüsch-Gerdes, S; Wessling, J | 1 |
Debois, H; Fendler, JP; Kepenekian, G; Mége, JL | 1 |
Grosset, J; Ji, B; Truffot-Pernot, C | 2 |
Chan, CY; Cheung, SW; Kwan, SY; Lee, J; Wong, PC; Yew, WW | 1 |
Tsukamura, M | 2 |
Amano, H; Nakamura, E; Tsukamura, M; Yoshii, S | 1 |
6 review(s) available for ofloxacin and Koch's Disease
Article | Year |
---|---|
Recent advances in antitubercular natural products.
Topics: Animals; Antitubercular Agents; Biological Products; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Mycobacterium tuberculosis; Tuberculosis | 2012 |
Fluoroquinolone derivatives and their anti-tubercular activities.
Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis | 2018 |
An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review.
Topics: Animals; Antitubercular Agents; Drug Design; Drug Discovery; Humans; Mycobacterium tuberculosis; Piperazine; Structure-Activity Relationship; Tuberculosis | 2021 |
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Levofloxacin; Ofloxacin; Pyrazinamide; Tuberculosis | 2010 |
Levofloxacin.
Topics: Animals; Antitubercular Agents; Humans; Levofloxacin; Ofloxacin; Treatment Outcome; Tuberculosis | 2008 |
[Ofloxacin in mycobacteriosis therapy].
Topics: Animals; Anti-Infective Agents; Clinical Trials as Topic; Disease Models, Animal; Humans; Leprosy, Tuberculoid; Mice; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium Infections; Ofloxacin; Topoisomerase II Inhibitors; Tuberculosis | 1997 |
3 trial(s) available for ofloxacin and Koch's Disease
Article | Year |
---|---|
Multiple drug hypersensitivity reactions to anti-tuberculosis drugs: five cases in HIV-infected patients.
Topics: Adult; Antitubercular Agents; Coinfection; Drug Eruptions; Drug Hypersensitivity; Edema; Eosinophilia; Female; Fever; HIV Infections; Humans; Male; Ofloxacin; Peripheral Nervous System Diseases; Pruritus; Skin Tests; South Africa; Stevens-Johnson Syndrome; Streptomycin; Tuberculosis | 2012 |
Susceptibility to levofloxacin of Myocobacterium tuberculosis isolates from patients with HIV-related tuberculosis and characterization of a strain with levofloxacin monoresistance. Community Programs for Clinical Research on AIDS 019 and the AIDS Clinica
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; In Vitro Techniques; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sputum; Tuberculosis | 1997 |
[Antituberculosis effect of levofloxacin].
Topics: Adolescent; Adult; Aged; Animals; Antitubercular Agents; Humans; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Tuberculosis | 2000 |
70 other study(ies) available for ofloxacin and Koch's Disease
Article | Year |
---|---|
Moxifloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis: evaluation of in vitro and pharmacodynamic indices that best predict in vivo efficacy.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoroquinolones; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Predictive Value of Tests; Quinolines; Time Factors; Tuberculosis | 2007 |
Development of 2-(4-oxoquinazolin-3(4H)-yl)acetamide derivatives as novel enoyl-acyl carrier protein reductase (InhA) inhibitors for the treatment of tuberculosis.
Topics: Acetamides; Animals; Bacterial Proteins; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Oxidoreductases; Quinazolines; Structure-Activity Relationship; Tuberculosis | 2014 |
Development of benzo[d]oxazol-2(3H)-ones derivatives as novel inhibitors of Mycobacterium tuberculosis InhA.
Topics: Animals; Antitubercular Agents; Bacterial Proteins; Benzoxazoles; Cell Line; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; Structure-Activity Relationship; Tuberculosis | 2014 |
Development of gallic acid formazans as novel enoyl acyl carrier protein reductase inhibitors for the treatment of tuberculosis.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Binding Sites; Catalytic Domain; Formazans; Gallic Acid; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; RAW 264.7 Cells; Tuberculosis | 2017 |
Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China.
Topics: Adult; Amikacin; Antitubercular Agents; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis; Whole Genome Sequencing | 2020 |
Acceptability of levofloxacin, moxifloxacin and linezolid among children and adolescents treated for TB.
Topics: Adolescent; Anti-Bacterial Agents; Aza Compounds; Child; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Tuberculosis | 2020 |
Double mutation in DNA gyrase confers moxifloxacin resistance and decreased fitness of Mycobacterium smegmatis.
Topics: DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Genetic Fitness; Genomics; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Ofloxacin; Sequence Analysis, DNA; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2017 |
PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis.
Topics: Antitubercular Agents; Base Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Genetic Variation; Humans; India; Isoniazid; Microbial Sensitivity Tests; Mitoxantrone; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rifampin; Sequence Analysis; Streptomycin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2017 |
Evaluation of Thin Layer Agar 7H11 for Direct Susceptibility Testing of Mycobacterium Tuberculosis Complex against Second Line Anti Tuberculosis Drugs on Smear Positive Specimens.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antitubercular Agents; Bacteriological Techniques; Chromatography, Thin Layer; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Sensitivity and Specificity; Sputum; Tuberculosis; Young Adult | 2019 |
Contribution of moxifloxacin or levofloxacin in second-line regimens with or without continuation of pyrazinamide in murine tuberculosis.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoroquinolones; Levofloxacin; Mice; Mice, Inbred BALB C; Moxifloxacin; Ofloxacin; Pyrazinamide; Quinolines; Treatment Outcome; Tuberculosis | 2013 |
Fluoroquinolone susceptibility in Mycobacterium tuberculosis after pre-diagnosis exposure to older- versus newer-generation fluoroquinolones.
Topics: Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Case-Control Studies; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Tuberculosis | 2013 |
Rationalizing use of fluoroquinolones and pyrazinamide in the battle against multidrug-resistant tuberculosis.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Female; Fluoroquinolones; Moxifloxacin; Ofloxacin; Pyrazinamide; Quinolines; Tuberculosis | 2013 |
Impact of fluoroquinolone resistance on bactericidal and sterilizing activity of a moxifloxacin-containing regimen in murine tuberculosis.
Topics: Amikacin; Animals; Antitubercular Agents; Aza Compounds; DNA Gyrase; Drug Administration Schedule; Drug Resistance, Bacterial; Ethionamide; Female; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Recurrence; Rodent Diseases; Survival Analysis; Tuberculosis | 2013 |
Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India.
Topics: Antitubercular Agents; Cycloserine; Drug Stability; Drug Storage; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; India; Isoniazid; Levofloxacin; Ofloxacin; Pyrazinamide; Rifampin; Spectrophotometry; Tuberculosis | 2013 |
First proficiency testing of second-line anti-tuberculosis drug susceptibility testing in 12 provinces of China.
Topics: Amikacin; Antitubercular Agents; Capreomycin; China; Drug Resistance, Bacterial; Humans; Kanamycin; Laboratory Proficiency Testing; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Observer Variation; Ofloxacin; Predictive Value of Tests; Quality Control; Quality Indicators, Health Care; Reproducibility of Results; Tuberculosis | 2013 |
Synthesis, characterization and in vitro extracellular and intracellular activity against Mycobacterium tuberculosis infection of new second-line antitubercular drug-palladium complexes.
Topics: Antitubercular Agents; Capreomycin; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Palladium; Particle Size; Solubility; Tuberculosis | 2014 |
Prevalence of gyrA and B gene mutations in fluoroquinolone-resistant and -sensitive clinical isolates of Mycobacterium tuberculosis and their relationship with MIC of ofloxacin.
Topics: Antitubercular Agents; Base Sequence; Codon; DNA Gyrase; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Prevalence; Tuberculosis | 2015 |
Characterization of extensively drug-resistant Mycobacterium tuberculosis isolates circulating in Siberia.
Topics: Adult; Amikacin; Antitubercular Agents; Capreomycin; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Genotype; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Minisatellite Repeats; Mutation; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Siberia; Tuberculosis; Young Adult | 2014 |
Sensititre® MYCOTB MIC plate for drug susceptibility testing of Mycobacterium tuberculosis complex isolates.
Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis | 2016 |
A novel resistance mutation in eccC5 of the ESX-5 secretion system confers ofloxacin resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Bacterial Secretion Systems; Case-Control Studies; DNA Mutational Analysis; Drug Resistance, Bacterial; Genome, Bacterial; Humans; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Mutation, Missense; Mycobacterium tuberculosis; Ofloxacin; Sequence Analysis, DNA; Tennessee; Tuberculosis; Virulence Factors | 2016 |
In vivo Mycobacterium tuberculosis fluoroquinolone resistance emergence: a complex phenomenon poorly detected by current diagnostic tests.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genotyping Techniques; Mice; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Selection, Genetic; Tuberculosis | 2016 |
Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis.
Topics: Administration, Inhalation; Administration, Oral; Aerosols; Animals; Anti-Bacterial Agents; Cell Line; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Hyaluronic Acid; Injections, Intravenous; Lactose; Lung; Macrophages, Alveolar; Mice; Microspheres; Nebulizers and Vaporizers; Ofloxacin; Particle Size; Rats; Rats, Sprague-Dawley; Technology, Pharmaceutical; Tissue Distribution; Tuberculosis | 2008 |
Molecular characterization of emerging non-levofloxacin-susceptible pneumococci isolated from children in South Africa.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; Carrier State; Child; Child, Preschool; Cluster Analysis; DNA Fingerprinting; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genotype; Humans; Infant; Infant, Newborn; Levofloxacin; Microbial Sensitivity Tests; Mutation, Missense; Ofloxacin; Pneumococcal Infections; Sequence Analysis, DNA; Serotyping; South Africa; Streptococcus pneumoniae; Tuberculosis | 2009 |
Safety of fluoroquinolone use in patients with hepatotoxicity induced by anti-tuberculosis regimens.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anti-Bacterial Agents; Antitubercular Agents; Aspartate Aminotransferases; Aza Compounds; Ethambutol; Female; Fluoroquinolones; Hepatic Insufficiency; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Streptomycin; Treatment Outcome; Tuberculosis; Young Adult | 2009 |
Multicenter evaluation of Bactec MGIT 960 system for second-line drug susceptibility testing of Mycobacterium tuberculosis complex.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Ethionamide; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity; Tuberculosis | 2009 |
Should moxifloxacin be used for the treatment of extensively drug-resistant tuberculosis? An answer from a murine model.
Topics: Animals; Antitubercular Agents; Aza Compounds; DNA Gyrase; Enoxacin; Fluoroquinolones; Gatifloxacin; Mice; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2010 |
Association of mutation patterns in gyrA/B genes and ofloxacin resistance levels in Mycobacterium tuberculosis isolates from East China in 2009.
Topics: Antitubercular Agents; China; DNA Gyrase; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Polymorphism, Restriction Fragment Length; Tuberculosis | 2011 |
Comparison of the bactericidal activity of various fluoroquinolones against Mycobacterium tuberculosis in an in vitro experimental model.
Topics: Antitubercular Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Spain; Tuberculosis | 2011 |
[Evaluation of tuberculosis treatment including levofloxacin (LVFX) in cases who could not continue standard regimen].
Topics: Aged; Anti-Bacterial Agents; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Tuberculosis; Tuberculosis, Pulmonary | 2011 |
Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis.
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA, Bacterial; DNA, Superhelical; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis; Mycobacterium tuberculosis; Ofloxacin; Plasmids; Tuberculosis | 2012 |
[Efficacy and tolerance of rezonizate in complex with fluoroquinolones or mycobutin on a model of experimental murine tuberculosis].
Topics: Animals; Antibiotics, Antitubercular; Disease Models, Animal; Drug Therapy, Combination; Drug Tolerance; Fluoroquinolones; Gatifloxacin; Isoxazoles; Levofloxacin; Mice; Mycobacterium tuberculosis; Ofloxacin; Oxazolidinones; Rifabutin; Tuberculosis | 2011 |
gyrA/B fluoroquinolone resistance allele profiles amongst Mycobacterium tuberculosis isolates from mainland China.
Topics: Alleles; China; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis | 2012 |
Persister eradication: lessons from the world of natural products.
Topics: Anti-Bacterial Agents; Biofilms; Biological Products; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Microbial Viability; Mycobacterium tuberculosis; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Species Specificity; Time Factors; Tuberculosis | 2012 |
Study of the rifampin monoresistance mechanism in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Base Sequence; Biological Transport; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Escherichia coli; Ethambutol; Genotype; Isoniazid; Kanamycin; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Protein Structure, Secondary; Protein Structure, Tertiary; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis | 2013 |
[The outcome of a survey on the use of levofloxacin for the treatment of tuberculosis].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Data Collection; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome; Tuberculosis | 2012 |
Optimal treatment of systemic bacillus Calmette-Guérin infection: investigations in an animal model.
Topics: Animals; Cell Survival; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Mycobacterium bovis; Ofloxacin; Prednisolone; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Virulence | 2002 |
Bacteriological conversion in twenty urinary tuberculosis patients treated with ofloxacin, rifampin and isoniazid: a 10-year follow-up study.
Topics: Adult; Aged; Anti-Infective Agents, Urinary; Antitubercular Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Treatment Outcome; Tuberculosis; Urinary Tract Infections | 2002 |
In vitro activity of moxifloxacin, levofloxacin, gatifloxacin and linezolid against Mycobacterium tuberculosis.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Linezolid; Male; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Oxazolidinones; Quinolines; Tuberculosis | 2002 |
Population pharmacokinetics of antituberculous drugs and treatment of Mycobacterium bovis infection in bongo antelope (Tragelaphus eurycerus isaaci).
Topics: Amikacin; Animals; Antelopes; Antitubercular Agents; Area Under Curve; Ethambutol; Female; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis | 2002 |
The rapid development of fluoroquinolone resistance in M. tuberculosis.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Prostatitis; Tuberculosis | 2003 |
Multiplex PCR amplimer conformation analysis for rapid detection of gyrA mutations in fluoroquinolone-resistant Mycobacterium tuberculosis clinical isolates.
Topics: Anti-Infective Agents; DNA Gyrase; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; Tuberculosis | 2004 |
Chemotherapy of leprosy.
Topics: Anti-Bacterial Agents; Clofazimine; Dapsone; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Hypersensitivity; India; Leprosy; Minocycline; Nausea; Ofloxacin; Rifampin; Secondary Prevention; Tuberculosis; World Health Organization | 2004 |
Determination of in vitro synergy when three antimicrobial agents are combined against Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Drug Synergism; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis | 2005 |
Levofloxacin treatment of active tuberculosis and the risk of adverse events.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Case-Control Studies; Child; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome; Tuberculosis | 2005 |
Emergence of ofloxacin resistance in Mycobacterium tuberculosis clinical isolates from China as determined by gyrA mutation analysis using denaturing high-pressure liquid chromatography and DNA sequencing.
Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; DNA Gyrase; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Mutation, Missense; Mycobacterium tuberculosis; Ofloxacin; Point Mutation; Sequence Analysis, DNA; Tuberculosis | 2006 |
In vitro activity of ciprofloxacin, ofloxacin, levofloxacin, sparfloxacin and gatifloxacin against multidrug-resistant Mycobacterium tuberculosis in Rio de Janeiro Brazil.
Topics: AIDS-Related Opportunistic Infections; Brazil; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis | 2007 |
Lack of correlation between embB mutation and ethambutol MIC in Mycobacterium tuberculosis clinical isolates from China.
Topics: Antitubercular Agents; Bacterial Proteins; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pentosyltransferases; Rifampin; Tuberculosis | 2007 |
Sternal tuberculosis.
Topics: Abscess; Adult; Anti-Bacterial Agents; Antitubercular Agents; Drug Therapy, Combination; Humans; Male; Mycobacterium Infections; Mycobacterium tuberculosis; Ofloxacin; Osteomyelitis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sternum; Thorax; Tomography, X-Ray Computed; Tuberculosis; Vancomycin | 2009 |
Increasing outpatient fluoroquinolone exposure before tuberculosis diagnosis and impact on culture-negative disease.
Topics: Adult; Aged; Ciprofloxacin; Female; Fluoroquinolones; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Mycobacterium tuberculosis; Ofloxacin; Outpatients; Pharmacy; Risk Factors; Tennessee; Time Factors; Tuberculosis | 2007 |
In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis.
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Isomerism; Isoniazid; Levofloxacin; Lung; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Spleen; Splenomegaly; Survival Rate; Tuberculosis | 1995 |
[Comparison of in-vitro and in-vivo activities of enoxacin and ofloxacin against the Mycobacterium tuberculosis].
Topics: Animals; Antitubercular Agents; Enoxacin; Female; Male; Mice; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis | 1995 |
[Immunotropic activity of antimicrobial agents used in tuberculosis].
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Cefotaxime; Cephalosporins; Erythromycin; Isoniazid; Macrophages; Mice; Ofloxacin; Time Factors; Tuberculosis | 1996 |
Roxithromycin alone and in combination with either ethambutol or levofloxacin for disseminated Mycobacterium avium infections in beige mice.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacteremia; Colony Count, Microbial; Drug Combinations; Ethambutol; Levofloxacin; Mice; Mycobacterium avium; Ofloxacin; Roxithromycin; Spleen; Tuberculosis | 1996 |
[In vivo activities of benzoxazinorifamycin KRM-1648, clarithromycin, and levofloxacin, or combination of KRM-1648 with diclofenac sodium against Mycobacterium avium infection induced in mice].
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Clarithromycin; Diclofenac; Drug Therapy, Combination; Female; Levofloxacin; Mice; Mice, Inbred BALB C; Mycobacterium avium; Ofloxacin; Rifamycins; Tuberculosis | 1997 |
Antimicrobial activities of benzoxazinorifamycin KRM-1648, clarithromycin and levofloxacin against intracellular Mycobacterium avium complex phagocytosed by murine peritoneal macrophages.
Topics: Animals; Anti-Bacterial Agents; Clarithromycin; Female; Levofloxacin; Lung; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium avium; Ofloxacin; Phagocytosis; Rifamycins; Tuberculosis | 1998 |
[Experimental study on the antituberculous activity of ofloxacins].
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Ethambutol; Female; Male; Mice; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis | 1997 |
Comparative antimycobacterial activities of ofloxacin, ciprofloxacin and grepafloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Humans; Macrophages; Microbial Sensitivity Tests; Monocytes; Mycobacterium; Mycobacterium avium Complex; Mycobacterium Infections, Nontuberculous; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin; Piperazines; Tuberculosis | 1999 |
Tuberculosis in orthotopic liver transplant patients: increased toxicity of recommended agents; cure of disseminated infection with nonconventional regimens.
Topics: Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ethambutol; Female; Humans; Liver; Liver Transplantation; Male; Middle Aged; Ofloxacin; Postoperative Complications; Retreatment; Treatment Outcome; Tuberculosis | 2000 |
Sources of variation in studies of the early bactericidal activity of antituberculosis drugs.
Topics: Anti-Infective Agents; Antitubercular Agents; Hong Kong; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; South Africa; Sputum; Tuberculosis | 2001 |
Antimicrobial activities of levofloxacin, clarithromycin, and KRM-1648 against Mycobacterium tuberculosis and Mycobacterium avium complex replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines.
Topics: Anti-Bacterial Agents; Cell Line; Clarithromycin; Epithelial Cells; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium tuberculosis; Ofloxacin; Pulmonary Alveoli; Rifamycins; Tuberculosis | 2000 |
CPCRA researchers present OI studies at Vancouver.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Candidiasis; Child; Clarithromycin; Clinical Trials as Topic; DNA, Viral; Drug Therapy, Combination; Ethambutol; Female; Fluconazole; Humans; Isoniazid; Molluscum Contagiosum; Molluscum contagiosum virus; Multicenter Studies as Topic; Mycobacterium avium-intracellulare Infection; Ofloxacin; Patient Compliance; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Tuberculosis | 1996 |
Limited tolerability of levofloxacin and pyrazinamide for multidrug-resistant tuberculosis prophylaxis in a solid organ transplant population.
Topics: Anti-Infective Agents; Antitubercular Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Levofloxacin; Male; Middle Aged; Ofloxacin; Organ Transplantation; Pyrazinamide; Retrospective Studies; Transplantation Immunology; Tuberculosis | 2002 |
Mycobacterium avium subsp. paratuberculosis infection in a patient with HIV, Germany.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Fatal Outcome; Germany; HIV Infections; Humans; Male; Mycobacterium avium subsp. paratuberculosis; Ofloxacin; Polymerase Chain Reaction; Tuberculosis | 2002 |
[Can ofloxacin constitute an alternative antitubercular treatment for BCG hepatitis?].
Topics: Aged; Anti-Infective Agents; Antitubercular Agents; Hepatitis; Humans; Male; Microbial Sensitivity Tests; Mycobacterium bovis; Ofloxacin; Tuberculosis | 2002 |
In vitro and in vivo activities of sparfloxacin (AT-4140) against Mycobacterium tuberculosis.
Topics: Animals; Anti-Infective Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Tuberculosis | 1991 |
Ofloxacin penetration into tuberculous pleural effusion.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pleural Effusion; Tuberculosis | 1991 |
Activities of pefloxacin and ofloxacin against mycobacteria: in vitro and mouse experiments.
Topics: Animals; Female; Mice; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin; Pefloxacin; Tuberculosis | 1991 |
[Therapeutic effect of ofloxacin on mice challenged by ofloxacin-resistant Mycobacterium bovis strains].
Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Mice; Mycobacterium bovis; Ofloxacin; Oxazines; Tuberculosis | 1987 |
Therapeutic effect of a new antibacterial substance ofloxacin (DL8280) on pulmonary tuberculosis.
Topics: Adult; Aged; Drug Resistance, Microbial; Female; Humans; Male; Middle Aged; Ofloxacin; Oxazines; Tuberculosis | 1985 |
Antituberculosis activity of ofloxacin (DL 8280) on experimental tuberculosis in mice.
Topics: Animals; Antitubercular Agents; Drug Evaluation, Preclinical; Liver; Mice; Mice, Inbred Strains; Mycobacterium tuberculosis; Ofloxacin; Oxazines; Tuberculosis | 1985 |