ofloxacin and Koch's Disease

ofloxacin has been researched along with Koch's Disease in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19903 (3.80)18.7374
1990's14 (17.72)18.2507
2000's27 (34.18)29.6817
2010's32 (40.51)24.3611
2020's3 (3.80)2.80

Authors

AuthorsStudies
Balasubramanian, V; Bharath, S; Gaonkar, S; Jayaram, R; Jayashree, R; Kaur, P; Mahesh, BN; Nandi, V; Shandil, RK; Suresh, BL1
Bocanegra-García, V; García, A; Palma-Nicolás, JP; Rivera, G1
Devi, PB; Jeankumar, VU; Pedgaonkar, GS; Renuka, J; Saxena, S; Sridevi, JP; Sriram, D; Yogeeswari, P2
Mahajan, SS; Saharan, VD1
Cheng, XW; Fan, YL; Feng, LS; Wu, JB; Zhang, FZ1
Dhawan, S; Girase, PS; Karpoormath, R; Kumar, V; Palkar, MB; Shinde, SR1
Gao, R; Guo, Y; Shen, X; Tan, G; Wang, H; Wu, X; Wu, Z; Yang, J; Yu, F1
Draper, HR; Garcia-Prats, AJ; Hesseling, AC; Schaaf, HS; van der Laan, LE; Winckler, JL1
Bao, L; Luo, T; Mi, Y; Peng, X; Sun, C; Wang, C; Yang, G; Yuan, J; Zhang, C1
Anupurba, S; Balgam, S; Fakir, NA; Gupta, A; Nema, V; Pal, SK; Pandey, D; Periera, M; Rathod, S; Sekar, G; Sinha, D; Sinha, P; SivaKumar, S; UmaDevi, KR1
Gardezi, AH; Hussain, A; Ikram, A; Khadim, MT; Satti, L; Zaman, G1
Ahmad, Z; Grosset, JH; Minkowski, A; Nuermberger, EL; Peloquin, CA; Tyagi, S1
Bian, A; Blackman, A; Eden, S; Maruri, F; Mitchel, E; Shintani, AK; Sterling, TR; van der Heijden, YF; Warkentin, JV1
Chang, KC; Dheda, K1
Aubry, A; Brossier, F; Chauffour, A; Fillion, A; Jarlier, V; Veziris, N1
Chandrasekaran, V; Dewan, P; Hemanth Kumar, AK; Ramachandran, G; Swaminathan, S; Thomas, A1
Chen, X; Huang, H; Jiang, GL; Kam, KM; Song, Y; Zhao, Y1
Blasi, P; Giovagnoli, S; Marenzoni, ML; Nocchetti, M; Ricci, M; Santi, C; Schoubben, A1
Dixit, P; Jain, A; Jaiswal, I; Prakash, S; Singh, M; Singh, P; Venkatesh, V1
Alkhovik, OI; Cherednichenko, AG; Dymova, MA; Filipenko, ML; Khrapov, EA; Petrenko, TI1
Chen, ST; Huang, HR; Jiang, GL; Ma, YF; Wang, GR; Yu, X1
Blackman, A; Eilertson, B; Guo, Y; Herrera, M; Maruri, F; Shyr, Y; Sterling, TR; van der Heijden, Y1
Aubry, A; Bernard, C; Brossier, F; Chauffour, A; Robert, J; Veziris, N1
Chung, SJ; Hwang, SM; Kim, DD; Shim, CK1
de Gouveia, L; du Plessis, M; Klugman, KP; von Gottberg, A; Wolter, N1
Chen, YC; Ho, CC; Hu, FC; Luh, KT; Yang, PC; Yu, CJ1
Bonato, D; Desmond, E; Gross, W; Lin, SY; Siddiqi, S1
Caminero, JA; Migliori, GB; Sotgiu, G; Zumla, A1
Aubry, A; Chauffour, A; Farinotti, R; Fernandez, C; Jarlier, V; Lott, MC; Poissy, J; Veziris, N1
Cui, Z; Hu, Z; Huang, X; Lu, J; Wang, J1
Cremades, R; Galiana, A; García-Pachón, E; López, P; Rodríguez, JC; Royo, G; Ruiz-García, M1
Akagawa, S; Ariga, H; Kaneko, Y; Kawabe, Y; Kawashima, M; Kunogi, M; Machida, K; Masuda, K; Matsui, H; Matsui, Y; Nagai, H; Nagayama, N; Nakajima, Y; Ohshima, N; Shimada, M; Suzuki, J; Tamura, A; Toyota, E1
Aubry, A; Bastian, S; Brossier, F; Jarlier, V; Mayer, C; Pantel, A; Petrella, S; Veziris, N1
Bugaenko, SE; Elistratova, NA; Maliev, BM; Mozhokina, GN; Sokolova, GB; Solov'eva, IP1
Du, Q; Fu, Y; Huang, H; Li, W; Liang, Q; Long, Q; Xie, J1
Dheda, K; Lehloenya, RJ; Todd, G; Wallace, J1
Keren, I; Lewis, K; Mulcahy, LR1
Lu, J; Pang, Y; Song, Y; Wang, S; Wang, Y; Zhao, Y1
Bohle, A; Durek, C; Jocham, D; Jurczok, A; Werner, H1
Castiñeiras, AA; Della-Latta, P; Herreras, A; Pérez-Pascual, P; Zarranz, JE1
López, M; Rodríguez, JC; Royo, G; Ruiz, M1
Aguilar, R; Auclair, B; Maslow, JN; Mikota, SK; Peloquin, CA1
Benjamin, WH; Bishai, WR; Dorman, SE; Ginsburg, AS; Hooper, N; Sterling, TR; Woolwine, SC1
Chan, EW; Chan, RC; Cheng, AF; Chin, ML; Hui, MM; Yew, WW1
Biswas, SK1
Bhusal, Y; Shiohira, CM; Yamane, N1
Elwood, RK; FitzGerald, JM; Marra, CA; Marra, F; Moadebi, S; Shi, P; Stark, G1
Kazumi, Y; Li, C; Shi, R; Sugawara, I; Zhang, J1
De Souza, MV; Junior, IN; Lourenço, MC1
Otomo, K; Shi, R; Sugawara, I; Zhang, G; Zhang, J1
Howell, JM; Mohammadi, A1
Baggett, P; Gaba, PD; Griffin, MR; Haley, C; Holt, E; Mitchel, E; Sterling, TR; Warkentin, J1
Grosset, J; JI, B; Lounis, N; Truffot-Pernot, C1
Li, H; Liu, S; Xu, G1
Aleksandrova, AE; Vinogradova, TI1
Bermudez, LE; Kolonoski, P; Young, LS1
Akaki, T; Kawahara, S; Sato, K; Shimizu, T; Tomioka, H1
Chirgwin, K; El Sadr, WM; Hafner, R; Heifets, LB; Klein, O; Kreiswirth, BN; Matts, JP; Musser, JM; Nelson, ET; Perlman, DC; Salomon, N; Telzak, EE1
Padełskaya, EN1
Akaki, T; Sato, K; Tomioka, H1
Duan, L; Li, H; Liang, G1
Fourche, J; Leblanc, F; Maugein, J; Pellegrin, JL; Vacher, S1
Emre, S; Meyers, BR; Miller, C; Papanicolaou, GA; Sheiner, P1
Mitchison, D; Sirgel, F; Venter, A1
Akaki, T; Kawahara, S; Sato, K; Tomioka, H1
Bowersox, J1
Duan, L; Lu, Y; Zhu, L1
Lou, HX; McKaveney, TP; Shullo, MA1
Domschke, W; Lügering, N; Richter, E; Rüsch-Gerdes, S; Wessling, J1
Debois, H; Fendler, JP; Kepenekian, G; Mége, JL1
Grosset, J; Ji, B; Truffot-Pernot, C2
Chan, CY; Cheung, SW; Kwan, SY; Lee, J; Wong, PC; Yew, WW1
Tsukamura, M2
Amano, H; Nakamura, E; Tsukamura, M; Yoshii, S1

Reviews

6 review(s) available for ofloxacin and Koch's Disease

ArticleYear
Recent advances in antitubercular natural products.
    European journal of medicinal chemistry, 2012, Volume: 49

    Topics: Animals; Antitubercular Agents; Biological Products; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Mycobacterium tuberculosis; Tuberculosis

2012
Fluoroquinolone derivatives and their anti-tubercular activities.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis

2018
An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Animals; Antitubercular Agents; Drug Design; Drug Discovery; Humans; Mycobacterium tuberculosis; Piperazine; Structure-Activity Relationship; Tuberculosis

2021
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
    The Lancet. Infectious diseases, 2010, Volume: 10, Issue:9

    Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Levofloxacin; Ofloxacin; Pyrazinamide; Tuberculosis

2010
Levofloxacin.
    Tuberculosis (Edinburgh, Scotland), 2008, Volume: 88, Issue:2

    Topics: Animals; Antitubercular Agents; Humans; Levofloxacin; Ofloxacin; Treatment Outcome; Tuberculosis

2008
[Ofloxacin in mycobacteriosis therapy].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1997, Volume: 42, Issue:11

    Topics: Animals; Anti-Infective Agents; Clinical Trials as Topic; Disease Models, Animal; Humans; Leprosy, Tuberculoid; Mice; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium Infections; Ofloxacin; Topoisomerase II Inhibitors; Tuberculosis

1997

Trials

3 trial(s) available for ofloxacin and Koch's Disease

ArticleYear
Multiple drug hypersensitivity reactions to anti-tuberculosis drugs: five cases in HIV-infected patients.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2012, Volume: 16, Issue:9

    Topics: Adult; Antitubercular Agents; Coinfection; Drug Eruptions; Drug Hypersensitivity; Edema; Eosinophilia; Female; Fever; HIV Infections; Humans; Male; Ofloxacin; Peripheral Nervous System Diseases; Pruritus; Skin Tests; South Africa; Stevens-Johnson Syndrome; Streptomycin; Tuberculosis

2012
Susceptibility to levofloxacin of Myocobacterium tuberculosis isolates from patients with HIV-related tuberculosis and characterization of a strain with levofloxacin monoresistance. Community Programs for Clinical Research on AIDS 019 and the AIDS Clinica
    AIDS (London, England), 1997, Volume: 11, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; In Vitro Techniques; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sputum; Tuberculosis

1997
[Antituberculosis effect of levofloxacin].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2000, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Antitubercular Agents; Humans; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Tuberculosis

2000

Other Studies

70 other study(ies) available for ofloxacin and Koch's Disease

ArticleYear
Moxifloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis: evaluation of in vitro and pharmacodynamic indices that best predict in vivo efficacy.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoroquinolones; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Predictive Value of Tests; Quinolines; Time Factors; Tuberculosis

2007
Development of 2-(4-oxoquinazolin-3(4H)-yl)acetamide derivatives as novel enoyl-acyl carrier protein reductase (InhA) inhibitors for the treatment of tuberculosis.
    European journal of medicinal chemistry, 2014, Oct-30, Volume: 86

    Topics: Acetamides; Animals; Bacterial Proteins; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Oxidoreductases; Quinazolines; Structure-Activity Relationship; Tuberculosis

2014
Development of benzo[d]oxazol-2(3H)-ones derivatives as novel inhibitors of Mycobacterium tuberculosis InhA.
    Bioorganic & medicinal chemistry, 2014, Nov-01, Volume: 22, Issue:21

    Topics: Animals; Antitubercular Agents; Bacterial Proteins; Benzoxazoles; Cell Line; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; Structure-Activity Relationship; Tuberculosis

2014
Development of gallic acid formazans as novel enoyl acyl carrier protein reductase inhibitors for the treatment of tuberculosis.
    Bioorganic & medicinal chemistry letters, 2017, 02-15, Volume: 27, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Binding Sites; Catalytic Domain; Formazans; Gallic Acid; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; RAW 264.7 Cells; Tuberculosis

2017
Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020, Volume: 96

    Topics: Adult; Amikacin; Antitubercular Agents; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis; Whole Genome Sequencing

2020
Acceptability of levofloxacin, moxifloxacin and linezolid among children and adolescents treated for TB.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2020, 12-01, Volume: 24, Issue:12

    Topics: Adolescent; Anti-Bacterial Agents; Aza Compounds; Child; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Tuberculosis

2020
Double mutation in DNA gyrase confers moxifloxacin resistance and decreased fitness of Mycobacterium smegmatis.
    The Journal of antimicrobial chemotherapy, 2017, 07-01, Volume: 72, Issue:7

    Topics: DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Genetic Fitness; Genomics; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Ofloxacin; Sequence Analysis, DNA; Tuberculosis; Tuberculosis, Multidrug-Resistant

2017
PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis.
    Annals of clinical microbiology and antimicrobials, 2017, Aug-18, Volume: 16, Issue:1

    Topics: Antitubercular Agents; Base Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Genetic Variation; Humans; India; Isoniazid; Microbial Sensitivity Tests; Mitoxantrone; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rifampin; Sequence Analysis; Streptomycin; Tuberculosis; Tuberculosis, Multidrug-Resistant

2017
Evaluation of Thin Layer Agar 7H11 for Direct Susceptibility Testing of Mycobacterium Tuberculosis Complex against Second Line Anti Tuberculosis Drugs on Smear Positive Specimens.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2019, Volume: 29, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antitubercular Agents; Bacteriological Techniques; Chromatography, Thin Layer; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Sensitivity and Specificity; Sputum; Tuberculosis; Young Adult

2019
Contribution of moxifloxacin or levofloxacin in second-line regimens with or without continuation of pyrazinamide in murine tuberculosis.
    American journal of respiratory and critical care medicine, 2013, Jul-01, Volume: 188, Issue:1

    Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoroquinolones; Levofloxacin; Mice; Mice, Inbred BALB C; Moxifloxacin; Ofloxacin; Pyrazinamide; Quinolines; Treatment Outcome; Tuberculosis

2013
Fluoroquinolone susceptibility in Mycobacterium tuberculosis after pre-diagnosis exposure to older- versus newer-generation fluoroquinolones.
    International journal of antimicrobial agents, 2013, Volume: 42, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Case-Control Studies; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Tuberculosis

2013
Rationalizing use of fluoroquinolones and pyrazinamide in the battle against multidrug-resistant tuberculosis.
    American journal of respiratory and critical care medicine, 2013, Jul-01, Volume: 188, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Female; Fluoroquinolones; Moxifloxacin; Ofloxacin; Pyrazinamide; Quinolines; Tuberculosis

2013
Impact of fluoroquinolone resistance on bactericidal and sterilizing activity of a moxifloxacin-containing regimen in murine tuberculosis.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:9

    Topics: Amikacin; Animals; Antitubercular Agents; Aza Compounds; DNA Gyrase; Drug Administration Schedule; Drug Resistance, Bacterial; Ethionamide; Female; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Recurrence; Rodent Diseases; Survival Analysis; Tuberculosis

2013
Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India.
    Tropical medicine & international health : TM & IH, 2013, Volume: 18, Issue:9

    Topics: Antitubercular Agents; Cycloserine; Drug Stability; Drug Storage; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; India; Isoniazid; Levofloxacin; Ofloxacin; Pyrazinamide; Rifampin; Spectrophotometry; Tuberculosis

2013
First proficiency testing of second-line anti-tuberculosis drug susceptibility testing in 12 provinces of China.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2013, Volume: 17, Issue:11

    Topics: Amikacin; Antitubercular Agents; Capreomycin; China; Drug Resistance, Bacterial; Humans; Kanamycin; Laboratory Proficiency Testing; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Observer Variation; Ofloxacin; Predictive Value of Tests; Quality Control; Quality Indicators, Health Care; Reproducibility of Results; Tuberculosis

2013
Synthesis, characterization and in vitro extracellular and intracellular activity against Mycobacterium tuberculosis infection of new second-line antitubercular drug-palladium complexes.
    The Journal of pharmacy and pharmacology, 2014, Volume: 66, Issue:1

    Topics: Antitubercular Agents; Capreomycin; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Palladium; Particle Size; Solubility; Tuberculosis

2014
Prevalence of gyrA and B gene mutations in fluoroquinolone-resistant and -sensitive clinical isolates of Mycobacterium tuberculosis and their relationship with MIC of ofloxacin.
    The Journal of antibiotics, 2015, Volume: 68, Issue:1

    Topics: Antitubercular Agents; Base Sequence; Codon; DNA Gyrase; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Prevalence; Tuberculosis

2015
Characterization of extensively drug-resistant Mycobacterium tuberculosis isolates circulating in Siberia.
    BMC infectious diseases, 2014, Sep-03, Volume: 14

    Topics: Adult; Amikacin; Antitubercular Agents; Capreomycin; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Genotype; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Minisatellite Repeats; Mutation; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Siberia; Tuberculosis; Young Adult

2014
Sensititre® MYCOTB MIC plate for drug susceptibility testing of Mycobacterium tuberculosis complex isolates.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2016, Volume: 20, Issue:3

    Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis

2016
A novel resistance mutation in eccC5 of the ESX-5 secretion system confers ofloxacin resistance in Mycobacterium tuberculosis.
    The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:9

    Topics: Antitubercular Agents; Bacterial Proteins; Bacterial Secretion Systems; Case-Control Studies; DNA Mutational Analysis; Drug Resistance, Bacterial; Genome, Bacterial; Humans; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Mutation, Missense; Mycobacterium tuberculosis; Ofloxacin; Sequence Analysis, DNA; Tennessee; Tuberculosis; Virulence Factors

2016
In vivo Mycobacterium tuberculosis fluoroquinolone resistance emergence: a complex phenomenon poorly detected by current diagnostic tests.
    The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:12

    Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genotyping Techniques; Mice; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Selection, Genetic; Tuberculosis

2016
Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis.
    Journal of controlled release : official journal of the Controlled Release Society, 2008, Jul-14, Volume: 129, Issue:2

    Topics: Administration, Inhalation; Administration, Oral; Aerosols; Animals; Anti-Bacterial Agents; Cell Line; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Hyaluronic Acid; Injections, Intravenous; Lactose; Lung; Macrophages, Alveolar; Mice; Microspheres; Nebulizers and Vaporizers; Ofloxacin; Particle Size; Rats; Rats, Sprague-Dawley; Technology, Pharmaceutical; Tissue Distribution; Tuberculosis

2008
Molecular characterization of emerging non-levofloxacin-susceptible pneumococci isolated from children in South Africa.
    Journal of clinical microbiology, 2009, Volume: 47, Issue:5

    Topics: Adolescent; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; Carrier State; Child; Child, Preschool; Cluster Analysis; DNA Fingerprinting; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genotype; Humans; Infant; Infant, Newborn; Levofloxacin; Microbial Sensitivity Tests; Mutation, Missense; Ofloxacin; Pneumococcal Infections; Sequence Analysis, DNA; Serotyping; South Africa; Streptococcus pneumoniae; Tuberculosis

2009
Safety of fluoroquinolone use in patients with hepatotoxicity induced by anti-tuberculosis regimens.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Jun-01, Volume: 48, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anti-Bacterial Agents; Antitubercular Agents; Aspartate Aminotransferases; Aza Compounds; Ethambutol; Female; Fluoroquinolones; Hepatic Insufficiency; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Streptomycin; Treatment Outcome; Tuberculosis; Young Adult

2009
Multicenter evaluation of Bactec MGIT 960 system for second-line drug susceptibility testing of Mycobacterium tuberculosis complex.
    Journal of clinical microbiology, 2009, Volume: 47, Issue:11

    Topics: Amikacin; Antitubercular Agents; Capreomycin; Ethionamide; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity; Tuberculosis

2009
Should moxifloxacin be used for the treatment of extensively drug-resistant tuberculosis? An answer from a murine model.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Animals; Antitubercular Agents; Aza Compounds; DNA Gyrase; Enoxacin; Fluoroquinolones; Gatifloxacin; Mice; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Tuberculosis; Tuberculosis, Multidrug-Resistant

2010
Association of mutation patterns in gyrA/B genes and ofloxacin resistance levels in Mycobacterium tuberculosis isolates from East China in 2009.
    BMC infectious diseases, 2011, Mar-29, Volume: 11

    Topics: Antitubercular Agents; China; DNA Gyrase; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Polymorphism, Restriction Fragment Length; Tuberculosis

2011
Comparison of the bactericidal activity of various fluoroquinolones against Mycobacterium tuberculosis in an in vitro experimental model.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:10

    Topics: Antitubercular Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Spain; Tuberculosis

2011
[Evaluation of tuberculosis treatment including levofloxacin (LVFX) in cases who could not continue standard regimen].
    Kekkaku : [Tuberculosis], 2011, Volume: 86, Issue:9

    Topics: Aged; Anti-Bacterial Agents; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Tuberculosis; Tuberculosis, Pulmonary

2011
Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:4

    Topics: Anti-Bacterial Agents; DNA Gyrase; DNA, Bacterial; DNA, Superhelical; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis; Mycobacterium tuberculosis; Ofloxacin; Plasmids; Tuberculosis

2012
[Efficacy and tolerance of rezonizate in complex with fluoroquinolones or mycobutin on a model of experimental murine tuberculosis].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2011, Volume: 56, Issue:7-8

    Topics: Animals; Antibiotics, Antitubercular; Disease Models, Animal; Drug Therapy, Combination; Drug Tolerance; Fluoroquinolones; Gatifloxacin; Isoxazoles; Levofloxacin; Mice; Mycobacterium tuberculosis; Ofloxacin; Oxazolidinones; Rifabutin; Tuberculosis

2011
gyrA/B fluoroquinolone resistance allele profiles amongst Mycobacterium tuberculosis isolates from mainland China.
    International journal of antimicrobial agents, 2012, Volume: 39, Issue:6

    Topics: Alleles; China; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis

2012
Persister eradication: lessons from the world of natural products.
    Methods in enzymology, 2012, Volume: 517

    Topics: Anti-Bacterial Agents; Biofilms; Biological Products; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Microbial Viability; Mycobacterium tuberculosis; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Species Specificity; Time Factors; Tuberculosis

2012
Study of the rifampin monoresistance mechanism in Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Antitubercular Agents; Bacterial Proteins; Base Sequence; Biological Transport; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Escherichia coli; Ethambutol; Genotype; Isoniazid; Kanamycin; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Protein Structure, Secondary; Protein Structure, Tertiary; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis

2013
[The outcome of a survey on the use of levofloxacin for the treatment of tuberculosis].
    Kekkaku : [Tuberculosis], 2012, Volume: 87, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Data Collection; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome; Tuberculosis

2012
Optimal treatment of systemic bacillus Calmette-Guérin infection: investigations in an animal model.
    The Journal of urology, 2002, Volume: 168, Issue:2

    Topics: Animals; Cell Survival; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Mycobacterium bovis; Ofloxacin; Prednisolone; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Virulence

2002
Bacteriological conversion in twenty urinary tuberculosis patients treated with ofloxacin, rifampin and isoniazid: a 10-year follow-up study.
    International microbiology : the official journal of the Spanish Society for Microbiology, 2002, Volume: 5, Issue:3

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Antitubercular Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Treatment Outcome; Tuberculosis; Urinary Tract Infections

2002
In vitro activity of moxifloxacin, levofloxacin, gatifloxacin and linezolid against Mycobacterium tuberculosis.
    International journal of antimicrobial agents, 2002, Volume: 20, Issue:6

    Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Linezolid; Male; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Oxazolidinones; Quinolines; Tuberculosis

2002
Population pharmacokinetics of antituberculous drugs and treatment of Mycobacterium bovis infection in bongo antelope (Tragelaphus eurycerus isaaci).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2002, Volume: 33, Issue:3

    Topics: Amikacin; Animals; Antelopes; Antitubercular Agents; Area Under Curve; Ethambutol; Female; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis

2002
The rapid development of fluoroquinolone resistance in M. tuberculosis.
    The New England journal of medicine, 2003, Nov-13, Volume: 349, Issue:20

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Prostatitis; Tuberculosis

2003
Multiplex PCR amplimer conformation analysis for rapid detection of gyrA mutations in fluoroquinolone-resistant Mycobacterium tuberculosis clinical isolates.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:2

    Topics: Anti-Infective Agents; DNA Gyrase; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; Tuberculosis

2004
Chemotherapy of leprosy.
    Journal of the Indian Medical Association, 2004, Volume: 102, Issue:12

    Topics: Anti-Bacterial Agents; Clofazimine; Dapsone; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Hypersensitivity; India; Leprosy; Minocycline; Nausea; Ofloxacin; Rifampin; Secondary Prevention; Tuberculosis; World Health Organization

2004
Determination of in vitro synergy when three antimicrobial agents are combined against Mycobacterium tuberculosis.
    International journal of antimicrobial agents, 2005, Volume: 26, Issue:4

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Drug Synergism; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis

2005
Levofloxacin treatment of active tuberculosis and the risk of adverse events.
    Chest, 2005, Volume: 128, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Case-Control Studies; Child; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome; Tuberculosis

2005
Emergence of ofloxacin resistance in Mycobacterium tuberculosis clinical isolates from China as determined by gyrA mutation analysis using denaturing high-pressure liquid chromatography and DNA sequencing.
    Journal of clinical microbiology, 2006, Volume: 44, Issue:12

    Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; DNA Gyrase; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Mutation, Missense; Mycobacterium tuberculosis; Ofloxacin; Point Mutation; Sequence Analysis, DNA; Tuberculosis

2006
In vitro activity of ciprofloxacin, ofloxacin, levofloxacin, sparfloxacin and gatifloxacin against multidrug-resistant Mycobacterium tuberculosis in Rio de Janeiro Brazil.
    Medecine et maladies infectieuses, 2007, Volume: 37, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Brazil; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis

2007
Lack of correlation between embB mutation and ethambutol MIC in Mycobacterium tuberculosis clinical isolates from China.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Antitubercular Agents; Bacterial Proteins; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pentosyltransferases; Rifampin; Tuberculosis

2007
Sternal tuberculosis.
    The Journal of emergency medicine, 2009, Volume: 36, Issue:4

    Topics: Abscess; Adult; Anti-Bacterial Agents; Antitubercular Agents; Drug Therapy, Combination; Humans; Male; Mycobacterium Infections; Mycobacterium tuberculosis; Ofloxacin; Osteomyelitis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sternum; Thorax; Tomography, X-Ray Computed; Tuberculosis; Vancomycin

2009
Increasing outpatient fluoroquinolone exposure before tuberculosis diagnosis and impact on culture-negative disease.
    Archives of internal medicine, 2007, Nov-26, Volume: 167, Issue:21

    Topics: Adult; Aged; Ciprofloxacin; Female; Fluoroquinolones; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Mycobacterium tuberculosis; Ofloxacin; Outpatients; Pharmacy; Risk Factors; Tennessee; Time Factors; Tuberculosis

2007
In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6

    Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Isomerism; Isoniazid; Levofloxacin; Lung; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Spleen; Splenomegaly; Survival Rate; Tuberculosis

1995
[Comparison of in-vitro and in-vivo activities of enoxacin and ofloxacin against the Mycobacterium tuberculosis].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1995, Volume: 18, Issue:3

    Topics: Animals; Antitubercular Agents; Enoxacin; Female; Male; Mice; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis

1995
[Immunotropic activity of antimicrobial agents used in tuberculosis].
    Problemy tuberkuleza, 1996, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Cefotaxime; Cephalosporins; Erythromycin; Isoniazid; Macrophages; Mice; Ofloxacin; Time Factors; Tuberculosis

1996
Roxithromycin alone and in combination with either ethambutol or levofloxacin for disseminated Mycobacterium avium infections in beige mice.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacteremia; Colony Count, Microbial; Drug Combinations; Ethambutol; Levofloxacin; Mice; Mycobacterium avium; Ofloxacin; Roxithromycin; Spleen; Tuberculosis

1996
[In vivo activities of benzoxazinorifamycin KRM-1648, clarithromycin, and levofloxacin, or combination of KRM-1648 with diclofenac sodium against Mycobacterium avium infection induced in mice].
    Kekkaku : [Tuberculosis], 1997, Volume: 72, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Clarithromycin; Diclofenac; Drug Therapy, Combination; Female; Levofloxacin; Mice; Mice, Inbred BALB C; Mycobacterium avium; Ofloxacin; Rifamycins; Tuberculosis

1997
Antimicrobial activities of benzoxazinorifamycin KRM-1648, clarithromycin and levofloxacin against intracellular Mycobacterium avium complex phagocytosed by murine peritoneal macrophages.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Clarithromycin; Female; Levofloxacin; Lung; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium avium; Ofloxacin; Phagocytosis; Rifamycins; Tuberculosis

1998
[Experimental study on the antituberculous activity of ofloxacins].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1997, Volume: 20, Issue:2

    Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Ethambutol; Female; Male; Mice; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis

1997
Comparative antimycobacterial activities of ofloxacin, ciprofloxacin and grepafloxacin.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:5

    Topics: Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Humans; Macrophages; Microbial Sensitivity Tests; Monocytes; Mycobacterium; Mycobacterium avium Complex; Mycobacterium Infections, Nontuberculous; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin; Piperazines; Tuberculosis

1999
Tuberculosis in orthotopic liver transplant patients: increased toxicity of recommended agents; cure of disseminated infection with nonconventional regimens.
    Transplantation, 2000, Jan-15, Volume: 69, Issue:1

    Topics: Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ethambutol; Female; Humans; Liver; Liver Transplantation; Male; Middle Aged; Ofloxacin; Postoperative Complications; Retreatment; Treatment Outcome; Tuberculosis

2000
Sources of variation in studies of the early bactericidal activity of antituberculosis drugs.
    The Journal of antimicrobial chemotherapy, 2001, Volume: 47, Issue:2

    Topics: Anti-Infective Agents; Antitubercular Agents; Hong Kong; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; South Africa; Sputum; Tuberculosis

2001
Antimicrobial activities of levofloxacin, clarithromycin, and KRM-1648 against Mycobacterium tuberculosis and Mycobacterium avium complex replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines.
    International journal of antimicrobial agents, 2000, Volume: 16, Issue:1

    Topics: Anti-Bacterial Agents; Cell Line; Clarithromycin; Epithelial Cells; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium tuberculosis; Ofloxacin; Pulmonary Alveoli; Rifamycins; Tuberculosis

2000
CPCRA researchers present OI studies at Vancouver.
    NIAID AIDS agenda, 1996

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Candidiasis; Child; Clarithromycin; Clinical Trials as Topic; DNA, Viral; Drug Therapy, Combination; Ethambutol; Female; Fluconazole; Humans; Isoniazid; Molluscum Contagiosum; Molluscum contagiosum virus; Multicenter Studies as Topic; Mycobacterium avium-intracellulare Infection; Ofloxacin; Patient Compliance; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Tuberculosis

1996
Limited tolerability of levofloxacin and pyrazinamide for multidrug-resistant tuberculosis prophylaxis in a solid organ transplant population.
    Pharmacotherapy, 2002, Volume: 22, Issue:6

    Topics: Anti-Infective Agents; Antitubercular Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Levofloxacin; Male; Middle Aged; Ofloxacin; Organ Transplantation; Pyrazinamide; Retrospective Studies; Transplantation Immunology; Tuberculosis

2002
Mycobacterium avium subsp. paratuberculosis infection in a patient with HIV, Germany.
    Emerging infectious diseases, 2002, Volume: 8, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Fatal Outcome; Germany; HIV Infections; Humans; Male; Mycobacterium avium subsp. paratuberculosis; Ofloxacin; Polymerase Chain Reaction; Tuberculosis

2002
[Can ofloxacin constitute an alternative antitubercular treatment for BCG hepatitis?].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2002, Volume: 12, Issue:2

    Topics: Aged; Anti-Infective Agents; Antitubercular Agents; Hepatitis; Humans; Male; Microbial Sensitivity Tests; Mycobacterium bovis; Ofloxacin; Tuberculosis

2002
In vitro and in vivo activities of sparfloxacin (AT-4140) against Mycobacterium tuberculosis.
    Tubercle, 1991, Volume: 72, Issue:3

    Topics: Animals; Anti-Infective Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Tuberculosis

1991
Ofloxacin penetration into tuberculous pleural effusion.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:10

    Topics: Adult; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pleural Effusion; Tuberculosis

1991
Activities of pefloxacin and ofloxacin against mycobacteria: in vitro and mouse experiments.
    Tubercle, 1991, Volume: 72, Issue:1

    Topics: Animals; Female; Mice; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin; Pefloxacin; Tuberculosis

1991
[Therapeutic effect of ofloxacin on mice challenged by ofloxacin-resistant Mycobacterium bovis strains].
    Kekkaku : [Tuberculosis], 1987, Volume: 62, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Mice; Mycobacterium bovis; Ofloxacin; Oxazines; Tuberculosis

1987
Therapeutic effect of a new antibacterial substance ofloxacin (DL8280) on pulmonary tuberculosis.
    The American review of respiratory disease, 1985, Volume: 131, Issue:3

    Topics: Adult; Aged; Drug Resistance, Microbial; Female; Humans; Male; Middle Aged; Ofloxacin; Oxazines; Tuberculosis

1985
Antituberculosis activity of ofloxacin (DL 8280) on experimental tuberculosis in mice.
    The American review of respiratory disease, 1985, Volume: 132, Issue:4

    Topics: Animals; Antitubercular Agents; Drug Evaluation, Preclinical; Liver; Mice; Mice, Inbred Strains; Mycobacterium tuberculosis; Ofloxacin; Oxazines; Tuberculosis

1985