Page last updated: 2024-11-01

ofloxacin and Injuries, Tendon

ofloxacin has been researched along with Injuries, Tendon in 8 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"An 80-year-old man treated by levofloxacin developed multiple tendon ruptures."7.72Rupture of multiple tendons after levofloxacin therapy. ( Bitar, S; Braun, D; Cosserat, F; Gillet, P; Loeuille, D; Petitpain, N; Trechot, P, 2004)
" A few days before he had been treated with ciprofloxacine 500mg bid for chlamydial urethritis."3.74[Fluorquinolone associated tendon rupture]. ( Bürr, P; Haschke, M; Rätz Bravo, A; Stoll, R, 2008)
"A 72-year-old female dialysis patient with insulin-dependent diabetes mellitus who was under long-term medication with oral prednisolone due to chronic obstructive pulmonary disease was given levofloxacin for one week to treat an acute bronchitis (one 500 mg dose on the first day, 125 mg/day orally from second day onwards)."3.74[Fluoroquinolone-induced Achilles tendon rupture]. ( Maurin, N, 2008)
"An 80-year-old man treated by levofloxacin developed multiple tendon ruptures."3.72Rupture of multiple tendons after levofloxacin therapy. ( Bitar, S; Braun, D; Cosserat, F; Gillet, P; Loeuille, D; Petitpain, N; Trechot, P, 2004)
"Levofloxacin was found to be very safe with a low rate of hepatic abnormalities (1/650,000)."2.41Comparison of side effects of levofloxacin versus other fluoroquinolones. ( Carbon, C, 2001)
"We describe 7 Achilles tendinitis occurring during fluoroquinolone treatment."1.28Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy. ( Audisio, F; De Bandt, M; Hayem, G; Jorgensen, C; Kahn, MF; Meyer, O; Palazzo, E; Ribard, P, 1992)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's6 (75.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rätz Bravo, A1
Stoll, R1
Bürr, P1
Haschke, M1
Turker, T1
Kutz, JE1
Melhus, A1
Apelqvist, J1
Larsson, J1
Eneroth, M1
Braun, D1
Petitpain, N1
Cosserat, F1
Loeuille, D1
Bitar, S1
Gillet, P1
Trechot, P1
Vyas, H1
Krishnaswamy, G1
Maurin, N1
Carbon, C1
Ribard, P1
Audisio, F1
Kahn, MF1
De Bandt, M1
Jorgensen, C1
Hayem, G1
Meyer, O1
Palazzo, E1

Reviews

1 review available for ofloxacin and Injuries, Tendon

ArticleYear
Comparison of side effects of levofloxacin versus other fluoroquinolones.
    Chemotherapy, 2001, Volume: 47 Suppl 3

    Topics: Anti-Infective Agents; Cardiovascular System; Dermatitis, Phototoxic; Digestive System; Hepatocytes;

2001

Other Studies

7 other studies available for ofloxacin and Injuries, Tendon

ArticleYear
[Fluorquinolone associated tendon rupture].
    Praxis, 2008, Nov-05, Volume: 97, Issue:22

    Topics: Achilles Tendon; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Bacte

2008
Can oral levofloxacin cause of flexor digitorum profundus rupture?
    Medical hypotheses, 2011, Volume: 77, Issue:4

    Topics: Administration, Oral; Anti-Bacterial Agents; Finger Injuries; Humans; Levofloxacin; Ofloxacin; Ruptu

2011
Levofloxacin-associated Achilles tendon rupture and tendinopathy.
    Scandinavian journal of infectious diseases, 2003, Volume: 35, Issue:10

    Topics: Achilles Tendon; Aged; Aged, 80 and over; Anti-Infective Agents; Female; Humans; Levofloxacin; Male;

2003
Rupture of multiple tendons after levofloxacin therapy.
    Joint bone spine, 2004, Volume: 71, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Humans; Levofloxacin; Male; Ofloxacin; Risk Factors;

2004
Images in clinical medicine. Quinolone-associated rupture of the Achilles' tendon.
    The New England journal of medicine, 2007, Nov-15, Volume: 357, Issue:20

    Topics: Achilles Tendon; Aged, 80 and over; Anti-Bacterial Agents; Bronchitis; Female; Humans; Magnetic Reso

2007
[Fluoroquinolone-induced Achilles tendon rupture].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:6

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Bronchitis; Diabetes Mellitus, Type 1; Female; Humans;

2008
Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy.
    The Journal of rheumatology, 1992, Volume: 19, Issue:9

    Topics: Achilles Tendon; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Cystitis; Female; Human

1992