Page last updated: 2024-11-01

ofloxacin and Inflammatory Response Syndrome, Systemic

ofloxacin has been researched along with Inflammatory Response Syndrome, Systemic in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"Among patients receiving chemotherapy for solid tumors or lymphoma, the prophylactic use of levofloxacin reduces the incidence of fever, probable infection, and hospitalization."5.11Antibacterial prophylaxis after chemotherapy for solid tumors and lymphomas. ( Billingham, L; Bower, M; Cullen, M; Fernando, I; Gaunt, C; Gollins, S; Hastings, M; Huddart, R; Rea, D; Simmonds, P; Stanley, A; Steven, N; Stuart, N, 2005)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cullen, M1
Steven, N1
Billingham, L1
Gaunt, C1
Hastings, M1
Simmonds, P1
Stuart, N1
Rea, D1
Bower, M1
Fernando, I1
Huddart, R1
Gollins, S1
Stanley, A1
Andrès, E1
Gaunard, A1
Blicklé, JF1
Kuhnert, C1
Goichot, B1
Schlienger, JL1
Brogard, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Prospective Double-Blind, Placebo-Controlled Trial of Prophylactic Oral Levofloxacin Following Chemotherapy for Lymphoma and Solid Tumors[NCT00005590]Phase 30 participants Interventional1999-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ofloxacin and Inflammatory Response Syndrome, Systemic

ArticleYear
Antibacterial prophylaxis after chemotherapy for solid tumors and lymphomas.
    The New England journal of medicine, 2005, Sep-08, Volume: 353, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineopl

2005

Other Studies

1 other study available for ofloxacin and Inflammatory Response Syndrome, Systemic

ArticleYear
Systemic reactions after intravesical BCG instillation for bladder cancer.
    QJM : monthly journal of the Association of Physicians, 2001, Volume: 94, Issue:12

    Topics: Administration, Intravesical; Aged; Anti-Infective Agents; BCG Vaccine; Humans; Male; Middle Aged; O

2001