Page last updated: 2024-11-01

ofloxacin and Infectious Endophthalmitis

ofloxacin has been researched along with Infectious Endophthalmitis in 53 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Infectious Endophthalmitis: Infectious condition of the internal eye.

Research Excerpts

ExcerptRelevanceReference
"We investigated whether the foldable capsular vitreous body (FCVB) could release levofloxacin sustainably in vitro and inhibit endophthalmitis in rabbit models."7.79A preliminary study to treat severe endophthalmitis via a foldable capsular vitreous body with sustained levofloxacin release in rabbits. ( Feng, L; Gao, Q; Huang, X; Jiang, Z; Li, Y; Lin, J; Lin, X; Liu, Y; Wang, T; Xie, Z, 2013)
"5% levofloxacin versus combined treatment with vancomycin and ceftazidime in an experimental model of bacterial endophthalmitis."7.74Bactericidal effect of intravitreal levofloxacin in an experimental model of endophthalmitis. ( Abad, JL; Alió, JL; Fernandez, J; Ferrer, C; Rodríguez, A, 2008)
"Endogenous endophthalmitis is a rare complication of infective endocarditis and has been decreasing due to the availability of effective antibiotics."5.35Levofloxacin-resistant-Streptococcus mitis endophthalmitis: a unique presentation of bacterial endocarditis. ( Dinani, A; Ktaich, N; Rubin, D; Urban, C, 2009)
"This partially masked randomized placebo-controlled multinational clinical study was designed to evaluate prospectively the prophylactic effect of intracameral cefuroxime and/or perioperative topical levofloxacin on postoperative endophthalmitis after cataract surgery."5.12ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study. ( Barry, P; Gettinby, G; Lees, F; Peterson, M; Revie, CW; Seal, DV; Wilhelmus, KR, 2006)
"This partially masked randomized placebo-controlled multinational clinical study to evaluate prospectively the prophylactic effect of intracameral cefuroxime injection and/or perioperative levofloxacin eyedrops on the incidence of endophthalmitis after phacoemulsification cataract surgery began in September 2003 and was terminated early in January 2006."5.12ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study. ( Barry, P; Gettinby, G; Lees, F; Peterson, M; Revie, CW; Seal, DV, 2006)
"Use of intracameral cefuroxime at the end of surgery reduced the occurrence of postoperative endophthalmitis."5.12Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors. ( , 2007)
"Ofloxacin has the best aqueous penetration in human eyes, as compared with ciprofloxacin and tobramycin, which suggests ofloxacin could be the preferred topical medicine for the prevention and treatment of endophthalmitis."5.10[Aqueous humor penetration of topically applied ofloxacin, ciprofloxacin and tobramycin]. ( Wu, XD; Yang, YH; Yao, K; Zhang, Z, 2003)
" A MEDLINE search was conducted using the following search terms: moxifloxacin or gatifloxacin; levofloxacin; minimum inhibitory concentration or prevention or prophylaxis; keratitis or endophthalmitis."4.84Review of third-and fourth-generation fluoroquinolones in ophthalmology: in-vitro and in-vivo efficacy. ( Scoper, SV, 2008)
"We investigated whether the foldable capsular vitreous body (FCVB) could release levofloxacin sustainably in vitro and inhibit endophthalmitis in rabbit models."3.79A preliminary study to treat severe endophthalmitis via a foldable capsular vitreous body with sustained levofloxacin release in rabbits. ( Feng, L; Gao, Q; Huang, X; Jiang, Z; Li, Y; Lin, J; Lin, X; Liu, Y; Wang, T; Xie, Z, 2013)
"Our protocol to achieve high aqueous humor concentrations of levofloxacin may be favorable in preventing endophthalmitis after eye surgery."3.77Efficient penetration into aqueous humor by administration of oral and topical levofloxacin. ( Ishida, M; Iwaki, M; Kataoka, T; Niwa, K; Zako, M, 2011)
" In open eye surgery, an additional antibioprophylaxis is recommended: in cataract surgery, injection in the anterior chamber at the end of the procedure of 1mg of cefuroxime; in other open eye surgeries, only in case of risk factors for endophthalmitis, administration of 500 mg oral levofloxacin tablet 12 hours and two hours before surgery."3.77[Antibioprophylaxis in ocular surgery: AFSSAPS recommendations]. ( Cochereau, I; Hajjar, J; Korobelnik, JF; Robert, PY, 2011)
"To investigate the safety of intracameral injection of gatifloxacin, levofloxacin in a rabbit model as prophylaxis against endophthalmitis."3.75Safety of intracameral injection of gatifloxacin, levofloxacin on corneal endothelial structure and viability. ( Choi, JA; Chung, SK, 2009)
"5% levofloxacin versus combined treatment with vancomycin and ceftazidime in an experimental model of bacterial endophthalmitis."3.74Bactericidal effect of intravitreal levofloxacin in an experimental model of endophthalmitis. ( Abad, JL; Alió, JL; Fernandez, J; Ferrer, C; Rodríguez, A, 2008)
"3% gatifloxacin ophthalmic solution in preventing bacterial endophthalmitis in rabbits."3.74Prophylactic efficacy of ophthalmic quinolones in experimental endophthalmitis in rabbits. ( Kozai, S; Ohashi, Y; Sakaki, H; Suzuki, T; Tajika, T; Wada, T, 2008)
"To determine the in vitro efficacy of levofloxacin, ofloxacin, and ciprofloxacin against Streptococcus pneumoniae and Streptococcus viridans isolates recovered from clinical cases of keratitis and endophthalmitis."3.72Comparative in vitro activity of levofloxacin, ofloxacin, and ciprofloxacin against ocular streptococcal isolates. ( Alfonso, EC; Miller, D, 2004)
"Vitreous levels of ofloxacin were above the MIC(90) at 2 and 8 h in all groups for most of the common microorganisms causing endophthalmitis and also at 24 h in traumatized-infected eyes."3.70Ofloxacin levels after intravitreal injection. Effects of trauma and inflammation. ( Basci, NE; Bozkurt, A; Kortunay, S; Kurt, E; Oguz Kayaalp, S; Oztürk, F; Sami Ilker, S; Ubeyt Inan, U, 1999)
"This study aimed to investigate the penetration of topical and oral ofloxacin into aqueous humor and vitreous humor in post-traumatic endophthalmitis model in rabbits."3.70Penetration of topical and oral ofloxacin into the aqueous and vitreous humor of inflamed rabbit eyes. ( Başci, NE; Bozkurt, A; Ilker, SS; Inan, UU; Kortunay, MC; Kurt, E; Oztürk, F, 2000)
"25 %) of povidone-iodine (PI) eye drops, combined with 0."2.77Effectiveness of 1.25 % povidone-iodine combined with topical levofloxacin against conjunctival flora in intravitreal injection. ( Gomi, F; Ikuno, Y; Maeda, N; Nishida, K; Sawa, M; Tsujikawa, M, 2012)
"Endogenous endophthalmitis is a rare complication of infective endocarditis and has been decreasing due to the availability of effective antibiotics."1.35Levofloxacin-resistant-Streptococcus mitis endophthalmitis: a unique presentation of bacterial endocarditis. ( Dinani, A; Ktaich, N; Rubin, D; Urban, C, 2009)
"Ofloxacin levels were determined in aqueous humor, vitreous humor, and serum by a bioassay."1.29Effect of inflammation on intraocular penetration of intravenous ofloxacin in albino rabbits. ( Gatti, G; Panozzo, G, 1995)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.77)18.7374
1990's5 (9.43)18.2507
2000's35 (66.04)29.6817
2010's10 (18.87)24.3611
2020's1 (1.89)2.80

Authors

AuthorsStudies
Martin Hita, L1
Casanovas Moreno-Torre, I1
Molina Esteban, J1
Foronda García-Hidalgo, C1
Guillot Suay, V1
Navarro Mari, JM1
Plotas, P1
Makri, OE1
Georgalas, I1
Pharmakakis, N1
Vantarakis, A1
Georgakopoulos, CD1
Bashir, G1
Hussain, W1
Rizvi, A1
Jensen, MK2
Fiscella, RG2
Moshirfar, M2
Mooney, B2
Scoper, SV1
Tsuchiya, Y1
Kobayakawa, S1
Tsuji, A1
Tochikubo, T1
Lindstrom, RL1
Holland, EJ1
Lane, SS1
McCulley, JP1
Dinani, A1
Ktaich, N1
Urban, C1
Rubin, D1
Choi, JA1
Chung, SK1
George, JM1
Fiscella, R1
Blair, M1
Rodvold, K1
Ulanski, L1
Stokes, J1
Blair, N1
Pontiggia, L1
Ishida, M1
Kataoka, T1
Niwa, K1
Iwaki, M1
Zako, M1
Cochereau, I1
Korobelnik, JF1
Robert, PY1
Hajjar, J1
Jiang, Z2
Wang, P1
Pan, B1
Xie, Z2
Li, D1
Wang, T2
Liu, Y2
Yuan, Z1
Gao, Q2
Cernak, M1
Majtanova, N1
Cernak, A1
Majtan, J1
Ikuno, Y1
Sawa, M1
Tsujikawa, M1
Gomi, F1
Maeda, N1
Nishida, K1
Tasaka, Y1
Suzuki, T2
Kawasaki, S1
Uda, T1
Mito, T1
Uno, T1
Ohashi, Y2
Huang, X1
Feng, L1
Li, Y1
Lin, X1
Lin, J1
Kherani, F1
Kherani, A1
Gehrs, KM1
Heilskov, TW1
Sutphin, JE1
Wagoner, MD1
Yao, K1
Zhang, Z1
Yang, YH1
Wu, XD1
Miller, D1
Alfonso, EC1
Ferrer, C2
Ruiz-Moreno, JM1
Rodríguez, A2
Montero, J1
Alió, JL2
Crandall, AS1
Wallin, T1
Olson, RJ1
Pea, F1
Ferrari, E1
Pavan, F1
Roman-Pognuz, D1
Bandello, F1
Furlanut, M1
Barkana, Y1
Almer, Z1
Segal, O1
Lazarovitch, Z1
Avni, I1
Zadok, D1
Bloom, C1
Thomson, EC1
Main, J1
Izdebska, J1
Szaflik, JP1
Freisberg, L1
Starr, MB1
Katz, HR1
Seal, DV2
Barry, P2
Gettinby, G2
Lees, F2
Peterson, M2
Revie, CW2
Wilhelmus, KR1
Yağci, R1
Oflu, Y1
Dinçel, A1
Kaya, E1
Yağci, S1
Bayar, B1
Duman, S2
Bozkurt, A4
Bohigian, GM1
Colyer, MH1
Weber, ED1
Weichel, ED1
Dick, JS1
Bower, KS1
Ward, TP1
Haller, JA1
Spokes, DM1
Walters, G1
Altiparmak, UE1
Ozer, PA1
Ozkuyumcu, C1
Us, AD1
Aslan, BS1
Miño de Kaspar, H1
Kreutzer, TC1
Aguirre-Romo, I1
Ta, CN1
Dudichum, J1
Bayrhof, M1
Klauss, V1
Kampik, A1
Abad, JL1
Fernandez, J1
Wada, T1
Kozai, S1
Tajika, T1
Sakaki, H1
Sakai, H1
Mochizuki, K1
Torisaki, M1
Yamashita, Y1
Komatsu, M1
Tanahashi, T1
Gatti, G1
Panozzo, G1
Le Thi Huong, D1
Cassoux, N1
Kemali, Z1
Wechsler, B1
Blétry, O1
Le Hoang, P1
Piette, JC1
Oztürk, F3
Kortunay, S2
Kurt, E3
Ubeyt Inan, U1
Sami Ilker, S1
Basci, NE2
Oguz Kayaalp, S1
Inan, UU2
Ilker, SS2
Basci, N1
Kortunay, MC1
Tandon, A1
Tay-Kearney, ML1
Metcalf, C1
McAllister, L1
Mather, R1
Karenchak, LM1
Romanowski, EG1
Kowalski, RP2
Keverline, MR1
Dhaliwal, DK1
Fisch, A1
Lafaix, C1
Salvanet, A1
Cherifi, M1
Meulemans, A1
Bron, A1
Talon, D1
Delbosc, B1
Estavoyer, JM1
Kaya, G1
Royer, J1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intracameral Levofloxacin (0.5%) Versus Intracameral Cefuroxime (1mg/0.1ml) Effect on Corneal Endothelial Cell Count and Morphology in Uneventful Phacoemulsification[NCT04212078]Phase 1/Phase 2138 participants (Anticipated)Interventional2019-07-29Recruiting
To Determine the Effect of Honey Enema in the Treatment of Patients With Acute Pouchitis (Pilot Study)[NCT02201186]Phase 210 participants (Actual)Interventional2014-10-31Completed
The Effects on Betadine 5% Penetration When Using Lidocaine 2% Jelly Versus Topical Tetracaine 0.5% for Topical Phacoemulsification Cataract Surgery.[NCT00827073]40 participants (Actual)Interventional2008-11-30Completed
Antibiotic Prophylaxis for Cataract Surgery Version 7e January 22 2003[NCT00136344]35,000 participants Interventional2003-09-30Completed
Contribution of Fast Molecular Bacterial Identification by Real-time PCR in Managing of Postoperative Acute Endophthalmitis[NCT02850653]150 participants (Anticipated)Interventional2007-11-30Recruiting
Use of Intracameral Moxifloxacin for the Prevention of Acute Endophthalmitis Following Cataract Surgery: a Controlled and Randomized Clinical Trial[NCT02770729]Phase 33,640 participants (Actual)Interventional2017-01-31Terminated
Phase 4 Study on Effectiveness of Topical 0.5% Levofloxacin on Reduction of Preoperative Conjunctival Flora in Patients Scheduled for Intraocular Surgery[NCT00491049]Phase 4140 participants (Actual)Interventional2004-09-30Completed
Concentration of Ofloxacin Into the Aqueous Humour of Patients After Topical Instillation According to the Severity of Dry Eye Disease[NCT05213156]Phase 491 participants (Actual)Interventional2019-09-24Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Ln(Bacterial Colony Count) From Pre-antibiotic Administration to Post Study Medication Swabs

Within 3 hours from time of culture acquisition, the samples will be vortexed for 30 seconds and 100µl aliquots will be plated onto 5% sheep blood and chocolate agar plates. These plates will be incubated with 5% carbon dioxide at 35˚ C for 72 hours. After 72 hours all plates will be read for colony count and identification of all isolates will be performed using routine microbiological methods. The natural log of bacterial bacterial colony count will be used for the outcome measure. (NCT00827073)
Timeframe: (1) Pre-antibiotics swab, and (2) Post-study medication (pre surgery)

InterventionLn(bacterial colony count) (Mean)
Tetracaine 0.5% Drop-0.14
Lidocaine 2% Jelly-0.52

Number of Bacterial Species in Pre-antibiotic Administration and in Post Study Medication Swabs

(NCT00827073)
Timeframe: (1) Pre-antibiotics swab and (2) Post-study medication (pre surgery)

,
Interventionbacterial spceies (Mean)
pre number of bacterial spicespost surgery number of bacterial speices
Lidocaine 2% Jelly11
Tetracaine 0.5% Drop11

Reviews

2 reviews available for ofloxacin and Infectious Endophthalmitis

ArticleYear
Review of third-and fourth-generation fluoroquinolones in ophthalmology: in-vitro and in-vivo efficacy.
    Advances in therapy, 2008, Volume: 25, Issue:10

    Topics: Administration, Topical; Anti-Bacterial Agents; Aza Compounds; Endophthalmitis; Fluoroquinolones; Ga

2008
[Levofloxacin (oftaquix) a fluoroquinolone of a new generation in prevention of the postoperative endophthalmitis following uncomplicated cataract surgery--the study of the European Society of Cataract and Refractive Surgeons (ESCRS)].
    Klinika oczna, 2005, Volume: 107, Issue:4-6

    Topics: Administration, Topical; Anti-Bacterial Agents; Cefuroxime; Endophthalmitis; Europe; Humans; Injecti

2005

Trials

10 trials available for ofloxacin and Infectious Endophthalmitis

ArticleYear
Efficacy of Topical Ofloxacin 0.3 % Administration on Conjunctival Bacterial Flora in Diabetic Patients Undergoing Intravitreal Injections.
    Seminars in ophthalmology, 2017, Volume: 32, Issue:6

    Topics: Adult; Aged; Angiogenesis Inhibitors; Anti-Bacterial Agents; Bacteria; Conjunctiva; Diabetic Retinop

2017
Aqueous and vitreous penetration of linezolid and levofloxacin after oral administration.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2010, Volume: 26, Issue:6

    Topics: Acetamides; Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Aqueous Humor; Drug Therapy, C

2010
Honey prophylaxis reduces the risk of endophthalmitis during perioperative period of eye surgery.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:4

    Topics: Abies; Anti-Bacterial Agents; Cataract Extraction; Corynebacterium; Drug Evaluation; Endophthalmitis

2012
Effectiveness of 1.25 % povidone-iodine combined with topical levofloxacin against conjunctival flora in intravitreal injection.
    Japanese journal of ophthalmology, 2012, Volume: 56, Issue:5

    Topics: Angiogenesis Inhibitors; Anti-Infective Agents, Local; Antibodies, Monoclonal, Humanized; Bacteria;

2012
[Aqueous humor penetration of topically applied ofloxacin, ciprofloxacin and tobramycin].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2003, Volume: 39, Issue:12

    Topics: Administration, Topical; Aged; Aqueous Humor; Ciprofloxacin; Endophthalmitis; Female; Humans; Male;

2003
Levofloxacin disposition over time in aqueous humor of patients undergoing cataract surgery.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aqueous Humor; Cataract Extraction; Endophthalmitis;

2005
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime

2006
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime

2006
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:6

    Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis;

2007
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:6

    Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis;

2007
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:6

    Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis;

2007
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:6

    Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis;

2007
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:6

    Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis;

2007
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:6

    Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis;

2007
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:6

    Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis;

2007
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:6

    Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis;

2007
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:6

    Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis;

2007
A prospective randomized study to determine the efficacy of preoperative topical levofloxacin in reducing conjunctival bacterial flora.
    American journal of ophthalmology, 2008, Volume: 145, Issue:1

    Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteria; Bacteriologi

2008

Other Studies

41 other studies available for ofloxacin and Infectious Endophthalmitis

ArticleYear
Listeria monocytogenes, a rare cause of endophthalmitis.
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2020, Volume: 33, Issue:3

    Topics: Anti-Bacterial Agents; Endophthalmitis; Humans; Listeria monocytogenes; Listeriosis; Male; Microbial

2020
Bipolaris hawaiiensis keratomycosis and endophthalmitis.
    Mycopathologia, 2009, Volume: 167, Issue:1

    Topics: Agriculture; Anti-Bacterial Agents; Antifungal Agents; Ascomycota; Cornea; Corneal Injuries; Corneal

2009
Third- and fourth-generation fluoroquinolones: retrospective comparison of endophthalmitis after cataract surgery performed over 10 years.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Ciprof

2008
Preventive effect against post-cataract endophthalmitis: drug delivery intraocular lens versus intracameral antibiotics.
    Current eye research, 2008, Volume: 33, Issue:10

    Topics: Animals; Anterior Chamber; Anti-Bacterial Agents; Aqueous Humor; Biological Availability; Cataract E

2008
Fluoroquinolones and postoperative endophthalmitis.
    Journal of cataract and refractive surgery, 2009, Volume: 35, Issue:2

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Ciprofloxacin; Endophthalmitis; Eye In

2009
Fluoroquinolones and postoperative endophthalmitis.
    Journal of cataract and refractive surgery, 2009, Volume: 35, Issue:2

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Ciprofloxacin; Endophthalmitis; Eye In

2009
Levofloxacin-resistant-Streptococcus mitis endophthalmitis: a unique presentation of bacterial endocarditis.
    Journal of medical microbiology, 2009, Volume: 58, Issue:Pt 10

    Topics: Aged; Aged, 80 and over; Drug Resistance, Bacterial; Echocardiography; Endocarditis, Subacute Bacter

2009
Safety of intracameral injection of gatifloxacin, levofloxacin on corneal endothelial structure and viability.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2009, Volume: 25, Issue:5

    Topics: Animals; Anterior Chamber; Anti-Infective Agents; Cell Survival; Endophthalmitis; Endothelium, Corne

2009
Efficient penetration into aqueous humor by administration of oral and topical levofloxacin.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2011, Volume: 27, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cataract Extraction; Chromatog

2011
[Antibioprophylaxis in ocular surgery: AFSSAPS recommendations].
    Journal francais d'ophtalmologie, 2011, Volume: 34, Issue:6

    Topics: Administration, Oral; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract Extr

2011
[Antibioprophylaxis in ocular surgery. Recommendations].
    Journal francais d'ophtalmologie, 2011, Volume: 34, Issue:6

    Topics: Administration, Oral; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract Extraction; Cefuroxime

2011
Evaluation of levofloxacin release characteristics from a human foldable capsular vitreous body in vitro.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:1

    Topics: Anti-Bacterial Agents; Chromatography, Liquid; Delayed-Action Preparations; Dose-Response Relationsh

2012
Moxifloxacin as postoperative prophylaxis for Enterococcus faecalis-induced endophthalmitis after cataract surgery in aphakic rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2013, Volume: 29, Issue:4

    Topics: Administration, Ophthalmic; Animals; Anti-Bacterial Agents; Aphakia, Postcataract; Aza Compounds; Di

2013
A preliminary study to treat severe endophthalmitis via a foldable capsular vitreous body with sustained levofloxacin release in rabbits.
    Investigative ophthalmology & visual science, 2013, Jan-28, Volume: 54, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Ciliary Body; Colony Count, Microbial; Cytokines; Drug Delivery Syst

2013
Xanthomonas maltophilia endophthalmitis following penetrating corneal injury.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2002, Volume: 37, Issue:5

    Topics: Amphotericin B; Cornea; Corneal Injuries; Drug Therapy, Combination; Endophthalmitis; Eye Infections

2002
Comparative in vitro activity of levofloxacin, ofloxacin, and ciprofloxacin against ocular streptococcal isolates.
    Cornea, 2004, Volume: 23, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; Endophthalmitis; Humans; Keratitis; Levofloxacin; Microbial Se

2004
Postoperative Corynebacterium macginleyi endophthalmitis.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:11

    Topics: Aged; Aqueous Humor; Bacterial Typing Techniques; Cataract Extraction; Chronic Disease; Corynebacter

2004
A retrospective study of endophtalmitis rates comparing quinolone antibiotics.
    American journal of ophthalmology, 2005, Volume: 139, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Cross

2005
Reduction of conjunctival bacterial flora by povidone-iodine, ofloxacin and chlorhexidine in an outpatient setting.
    Acta ophthalmologica Scandinavica, 2005, Volume: 83, Issue:3

    Topics: Anti-Infective Agents, Local; Antibiotic Prophylaxis; Bacteria; Chlorhexidine; Colony Count, Microbi

2005
An elderly lady with sudden blindness and a sore foot.
    The Journal of infection, 2006, Volume: 52, Issue:2

    Topics: Administration, Topical; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Blindness; Ceftriaxon

2006
A retrospective study of endophthalmitis rates comparing quinolone antibiotics.
    American journal of ophthalmology, 2005, Volume: 140, Issue:4

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Utilization Review; Endophthalmitis; Eye Infections, Bact

2005
A retrospective study of endophthalmitis rates comparing quinolone antibiotics.
    American journal of ophthalmology, 2005, Volume: 140, Issue:4

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Utilization Review; Endophthalmitis; Eye Infections, Bact

2005
A retrospective study of endophthalmitis rates comparing quinolone antibiotics.
    American journal of ophthalmology, 2005, Volume: 140, Issue:4

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Utilization Review; Endophthalmitis; Eye Infections, Bact

2005
Penetration of second-, third-, and fourth-generation topical fluoroquinolone into aqueous and vitreous humour in a rabbit endophthalmitis model.
    Eye (London, England), 2007, Volume: 21, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Aqueous Humor; Aza Compounds; Ciprofloxacin; Disease Models, Animal;

2007
ESCRS study of endophthalmitis prophylaxis.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:9

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime

2006
Delayed intraocular foreign body removal without endophthalmitis during Operations Iraqi Freedom and Enduring Freedom.
    Ophthalmology, 2007, Volume: 114, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Aza Compounds; Combined Modality Therapy; Endophthalmitis; Eye Enuclea

2007
Prophylaxis of postoperative endophthalmitis.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:4

    Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E

2007
Postoperative endophthalmitis caused by Bacillus cereus and Chlamydia trachomatis.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:7

    Topics: Administration, Oral; Administration, Topical; Aged; Anti-Bacterial Agents; Bacillus cereus; Bacteri

2007
Bactericidal effect of intravitreal levofloxacin in an experimental model of endophthalmitis.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Endophthalmitis; Female; Levofloxacin; Male; Microbial

2008
Prophylactic efficacy of ophthalmic quinolones in experimental endophthalmitis in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2008, Volume: 24, Issue:3

    Topics: Animals; Anterior Chamber; Anti-Bacterial Agents; Biological Availability; Disease Progression; Endo

2008
Nontoxic intravitreal dose of ofloxacin for rabbit retina.
    Ophthalmic research, 1994, Volume: 26, Issue:6

    Topics: Animals; Electroretinography; Endophthalmitis; Evoked Potentials, Visual; Injections; Ofloxacin; Rab

1994
Effect of inflammation on intraocular penetration of intravenous ofloxacin in albino rabbits.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:2

    Topics: Animals; Bacterial Infections; Endophthalmitis; Eye; Ofloxacin; Rabbits

1995
[Endogenous infectious endophthalmitis].
    La Revue de medecine interne, 1998, Volume: 19, Issue:9

    Topics: Aged; Amphotericin B; Antifungal Agents; Candidiasis; Drug Therapy, Combination; Endophthalmitis; Fl

1998
Ofloxacin levels after intravitreal injection. Effects of trauma and inflammation.
    Ophthalmic research, 1999, Volume: 31, Issue:6

    Topics: Animals; Anti-Infective Agents; Endophthalmitis; Eye Injuries; Half-Life; Injections; Ofloxacin; Osm

1999
The effect of long-term use and inflammation on the ocular penetration of topical ofloxacin.
    Current eye research, 1999, Volume: 19, Issue:6

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Aqueous Humor; Endophthalmitis; Eye; Eye In

1999
Penetration of topical and oral ofloxacin into the aqueous and vitreous humor of inflamed rabbit eyes.
    International journal of pharmaceutics, 2000, Aug-25, Volume: 204, Issue:1-2

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Aqueous Humor; Endophthalmitis; Female; Mal

2000
Bacillus circulans endophthalmitis.
    Clinical & experimental ophthalmology, 2001, Volume: 29, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Bacillaceae Infections; Bacillus; Cephalosporins; Ce

2001
Fourth generation fluoroquinolones: new weapons in the arsenal of ophthalmic antibiotics.
    American journal of ophthalmology, 2002, Volume: 133, Issue:4

    Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Endophtha

2002
In vitro comparison of ciprofloxacin, ofloxacin, and povidone-iodine for surgical prophylaxis.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:6

    Topics: Anti-Infective Agents; Anti-Infective Agents, Local; Antibiotic Prophylaxis; Bacteria; Ciprofloxacin

2002
Ofloxacin in human aqueous humour and lens.
    The Journal of antimicrobial chemotherapy, 1987, Volume: 20, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aqueous Humor; Endophthalmitis; Humans; Lens,

1987
[Intracamera penetration of ofloxacin in man].
    Journal francais d'ophtalmologie, 1987, Volume: 10, Issue:6-7

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Infective Agents; Aqueous Humor; Endophthalmitis

1987