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ofloxacin and Infections, Staphylococcal Skin

ofloxacin has been researched along with Infections, Staphylococcal Skin in 8 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"Oral levofloxacin was compared to oral ciprofloxacin in a Staphylococcus aureus subcutaneous abscess model in rabbits."7.70Comparison of efficacies of oral levofloxacin and oral ciprofloxacin in a rabbit model of a staphylococcal abscess. ( Amaratunga, D; Barrett, JF; Fernandez, J; Frosco, M; Licata, L, 1999)
"Oral levofloxacin was compared to oral ciprofloxacin in a Staphylococcus aureus subcutaneous abscess model in rabbits."3.70Comparison of efficacies of oral levofloxacin and oral ciprofloxacin in a rabbit model of a staphylococcal abscess. ( Amaratunga, D; Barrett, JF; Fernandez, J; Frosco, M; Licata, L, 1999)
"Ofloxacin, a new pyridone-carboxylic acid derivative, was evaluated in descending nephritis and subcutaneous abscess models with Staphylococcus aureus in mice in comparison with norfloxacin."3.67Chemotherapeutic efficacy of ofloxacin on renal and subcutaneous infection models with Staphylococcus aureus in mice. ( Fujimoto, T; Katami, K; Osada, Y; Sato, M; Tachizawa, H; Tsumura, M; Une, T, 1986)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Trad, S1
Saadoun, D1
Barete, S1
Frances, C1
Piette, JC1
Wechsler, B1
Farrell, DJ1
Turner, LL1
Castanheira, M1
Jones, RN1
Fish, DN1
Sesso, R1
Parisio, K1
Dalboni, A1
Rabelo, T1
Barbosa, D1
Cendoroglo, M1
Pignatari, A1
Draibe, S1
Ajzen, H1
Nishijima, S1
Namura, S1
Mitsuya, K1
Asada, Y1
Fernandez, J1
Barrett, JF1
Licata, L1
Amaratunga, D1
Frosco, M1
Yamakawa, T1
Mitsuyama, J1
Hayashi, K1
Fujimoto, T1
Sato, M1
Katami, K1
Osada, Y1
Tsumura, M1
Tachizawa, H1
Une, T1

Reviews

1 review available for ofloxacin and Infections, Staphylococcal Skin

ArticleYear
Levofloxacin: update and perspectives on one of the original 'respiratory quinolones'.
    Expert review of anti-infective therapy, 2003, Volume: 1, Issue:3

    Topics: Animals; Drug Resistance, Microbial; Humans; Levofloxacin; Ofloxacin; Quinolones; Respiratory Tract

2003

Trials

1 trial available for ofloxacin and Infections, Staphylococcal Skin

ArticleYear
Effect of sodium fusidate and ofloxacin on Staphylococcus aureus colonization and infection in patients on continuous ambulatory peritoneal dialysis.
    Clinical nephrology, 1994, Volume: 41, Issue:6

    Topics: Administration, Oral; Administration, Topical; Adult; Catheters, Indwelling; Female; Fusidic Acid; H

1994

Other Studies

6 other studies available for ofloxacin and Infections, Staphylococcal Skin

ArticleYear
[Necrotizing folliculitis in Behçet's disease].
    La Revue de medecine interne, 2009, Volume: 30, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local; Bacterial Toxins; Behcet

2009
Activity of JNJ-Q2 against Staphylococcus aureus isolated from patients with acute bacterial skin and skin-structure infection obtained during a Phase 2 clinical trial.
    Diagnostic microbiology and infectious disease, 2012, Volume: 74, Issue:1

    Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levoflox

2012
The incidence of isolation of methicillin-resistant Staphylococcus aureus (MRSA) strains from skin infections during the past three years (1989-1991).
    The Journal of dermatology, 1993, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteriophage Typing; Child; Cilastatin; Coagulase; Colo

1993
Comparison of efficacies of oral levofloxacin and oral ciprofloxacin in a rabbit model of a staphylococcal abscess.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:3

    Topics: Abscess; Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Female; Levofloxacin; Micr

1999
In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinolone.
    The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:3

    Topics: Animals; Anti-Infective Agents; Clindamycin; Colony Count, Microbial; DNA Topoisomerase IV; Drug Res

2002
Chemotherapeutic efficacy of ofloxacin on renal and subcutaneous infection models with Staphylococcus aureus in mice.
    Chemotherapy, 1986, Volume: 32, Issue:3

    Topics: Abscess; Animals; Anti-Bacterial Agents; Autoradiography; Disease Models, Animal; Kinetics; Male; Mi

1986