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ofloxacin and Infections, Salmonella

ofloxacin has been researched along with Infections, Salmonella in 29 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"The recommended treatment for traveler's diarrhea is the combination of an appropriate antibiotic (usually a fluoroquinolone) and loperamide."9.12Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey. ( Frenck, RW; Johnston, JR; Monteville, MR; Putnam, SD; Riddle, MS; Rockabrand, DM; Sanders, JW; Tribble, DR; Ulukan, S, 2007)
"Eradication of non-typhoid salmonellae was evaluated in a randomized, double-blinded study of 49 patients with acute enteritis after therapy with ofloxacin 400 mg once daily for 5 or 10 days."9.09Eradication of non-typhoid salmonellae in acute enteritis after therapy with ofloxacin for 5 or 10 days. ( Digranes, A; Halstensen, A; Langeland, N; Peterson, LE; Rolstad, T; Solberg, CO; Voltersvik, P, 2000)
"The recommended treatment for traveler's diarrhea is the combination of an appropriate antibiotic (usually a fluoroquinolone) and loperamide."5.12Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey. ( Frenck, RW; Johnston, JR; Monteville, MR; Putnam, SD; Riddle, MS; Rockabrand, DM; Sanders, JW; Tribble, DR; Ulukan, S, 2007)
"Eradication of non-typhoid salmonellae was evaluated in a randomized, double-blinded study of 49 patients with acute enteritis after therapy with ofloxacin 400 mg once daily for 5 or 10 days."5.09Eradication of non-typhoid salmonellae in acute enteritis after therapy with ofloxacin for 5 or 10 days. ( Digranes, A; Halstensen, A; Langeland, N; Peterson, LE; Rolstad, T; Solberg, CO; Voltersvik, P, 2000)
"In the present study, 33 adult patients with salmonella infections consisting of 13 typhoid fever, 9 paratyphoid fever, 8 enterocolitis, 2 carriers, 1 acute gastroenteritis have been treated with ofloxacin."3.68[Ofloxacin treatment of salmonella infections]. ( Altay, G; Arman, D; Unlü, S, 1993)
"Levofloxacin's efficacy was inferior to azithromycin's efficacy, except in patients with no pathogen identified during the first 24 h of treatment or in patients with levofloxacin-susceptible Campylobacter isolates, in whom it appeared to be equal to azithromycin."2.73Traveler's diarrhea in Thailand: randomized, double-blind trial comparing single-dose and 3-day azithromycin-based regimens with a 3-day levofloxacin regimen. ( Armstrong, A; Baqar, S; Bodhidatta, L; Faix, DJ; Fox, A; Hshieh, P; Lawler, JV; Lebron, C; Lewis, M; Maley, EA; Mason, C; Nayak, G; Pang, LW; Pitarangsi, C; Sanders, JW; Scott, DA; Tribble, DR, 2007)
"The pefloxacin disk assay was approved and implemented by EUCAST (in 2014) and CLSI (in 2015)."1.42Development of a Pefloxacin Disk Diffusion Method for Detection of Fluoroquinolone-Resistant Salmonella enterica. ( Åhman, J; Kahlmeter, G; Matuschek, E; Petersen, A; Sjölund-Karlsson, M; Skov, R; Stegger, M; Torpdahl, M, 2015)
"In countries such as India, where Salmonella infections are endemic, a high index of suspicion should be always be maintained and the possibility of a Salmonella infection at an aberrant site where it is hardly expected should not be ruled out."1.38Epididymo-orchitis: an unusual manifestation of salmonellosis. ( Bansal, N; Chander, J; Kaistha, N, 2012)
"Sallmonela spondylodiscitis is a rare condition occur secondary to hematogenous spread after bacteremia episode."1.37Spondylodiscitis due to Sallmonela in an immunocompetent patient. ( Kasmi, G; Kraja, D; Leka, N; Melyshi, K; Shkurti-Leka, K; Vreto, G, 2011)
"Pelvis osteomyelitis is rare in childhood."1.37Salmonella pelvic osteomyelitis in an immunocompetent child. ( Campanacci, D; Canessa, C; Chiappini, E; Maglione, M; Resti, M; Trapani, S, 2011)
"We reported a case of salmonellosis treated with ofloxacin (OFLX) which showed excellent clinical and bacteriological effect in a 22 year-old Japanese male with Salmonellosis paratyphi A."1.28[Ofloxacin in the treatment of infection caused by Salmonella paratyphi A]. ( Akeda, H; Aoki, T; Honda, S; Okada, K; Sawae, Y; Takaki, K, 1991)
"Among them, 9 patients suffered from shigellosis (8 S."1.28[Treatment of salmonellosis and shigellosis with the new quinolones]. ( Biron, F; Boibieux, A; Peyramond, D; Tigaud, S, 1990)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's9 (31.03)18.2507
2000's10 (34.48)29.6817
2010's8 (27.59)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Sun, J1
Ren, Y1
Ji, J1
Guo, Y1
Sun, X1
Kuuliala, A1
Julkunen, H1
Paimela, L1
Peltomaa, R1
Kautiainen, H1
Repo, H1
Leirisalo-Repo, M1
Sjölund-Karlsson, M2
Howie, RL1
Crump, JA1
Whichard, JM1
Igbinosa, IH1
Skov, R1
Matuschek, E1
Åhman, J1
Petersen, A1
Stegger, M1
Torpdahl, M1
Kahlmeter, G1
Sanders, JW2
Frenck, RW1
Putnam, SD1
Riddle, MS1
Johnston, JR1
Ulukan, S1
Rockabrand, DM1
Monteville, MR1
Tribble, DR2
Béraud, G1
Iba Ba, J1
Legout, L1
Senneville, E1
Yazdanpanah, Y1
Mouton, Y1
Shkurti-Leka, K1
Kraja, D1
Leka, N1
Vreto, G1
Melyshi, K1
Kasmi, G1
Lebeaux, D1
Zarrouk, V1
Petrover, D1
Nicolas-Chanoine, MH1
Fantin, B1
Bansal, N1
Kaistha, N1
Chander, J1
Canessa, C1
Trapani, S1
Campanacci, D1
Chiappini, E1
Maglione, M1
Resti, M1
Ma, J1
Chan, JK1
Schoevaerdts, D1
Hanon, F1
Vanpee, D1
Swine, C1
Glupczynski, Y1
Vander Borght, T1
Marchandise, B1
Arora, A1
Singh, S1
Aggarwal, A1
Aggarwal, PK1
Candel, FJ1
Roca-Arbonés, V1
Núñez, MJ1
Arroyo, C1
Valdivia, A1
Téllez, MJ1
Picazo, JJ1
Pang, LW1
Mason, C1
Pitarangsi, C1
Baqar, S1
Armstrong, A1
Hshieh, P1
Fox, A1
Maley, EA1
Lebron, C1
Faix, DJ1
Lawler, JV1
Nayak, G1
Lewis, M1
Bodhidatta, L1
Scott, DA1
Fica, AE1
Horowitz, HW1
Lior, H1
Cabello, FC1
Unlü, S1
Arman, D1
Altay, G1
Fernández Guerrero, ML1
Torres Perea, R1
Verdejo Morcillo, C1
Fernández Roblas, R1
de Górgolas, M1
Lobzin, IuV1
Shetty, M1
Shivananda, PG1
Yang, J1
Baltatzis, S1
Foster, CS1
Voltersvik, P1
Halstensen, A1
Langeland, N1
Digranes, A1
Peterson, LE1
Rolstad, T1
Solberg, CO1
Flannery, MT1
Le, M1
Altus, P1
Wawruch, M1
Harnicarova, A1
Macekova, L1
Tisonova, J1
Biss, B1
Kriska, M1
Miragliotta, G1
Takaki, K1
Aoki, T1
Akeda, H1
Honda, S1
Okada, K1
Sawae, Y1
Biron, F1
Boibieux, A1
Tigaud, S1
Peyramond, D1
Löffler, A1
Grafvon Westphalen, H1

Trials

5 trials available for ofloxacin and Infections, Salmonella

ArticleYear
Double-blind, randomized, placebo-controlled study of three-month treatment with the combination of ofloxacin and roxithromycin in recent-onset reactive arthritis.
    Rheumatology international, 2013, Volume: 33, Issue:11

    Topics: Adult; Anti-Bacterial Agents; Arthritis, Reactive; Campylobacter Infections; Chlamydia Infections; D

2013
Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Volume: 45, Issue:3

    Topics: Adult; Azithromycin; Campylobacter Infections; Diarrhea; Double-Blind Method; Drug Therapy, Combinat

2007
Traveler's diarrhea in Thailand: randomized, double-blind trial comparing single-dose and 3-day azithromycin-based regimens with a 3-day levofloxacin regimen.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Feb-01, Volume: 44, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Azithromycin; Campylobacter Infections; Campylobacter jejuni; Communit

2007
[An attempt to use ofloxacin in the treatment of acute intestinal infections].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1996, Volume: 41, Issue:9

    Topics: Acute Disease; Anti-Infective Agents; Chlamydia Infections; Drug Resistance, Microbial; Dysentery, B

1996
Eradication of non-typhoid salmonellae in acute enteritis after therapy with ofloxacin for 5 or 10 days.
    The Journal of antimicrobial chemotherapy, 2000, Volume: 46, Issue:3

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Double-Blind Method; Enteritis; Humans; Middle Ag

2000

Other Studies

24 other studies available for ofloxacin and Infections, Salmonella

ArticleYear
A novel concentration gradient microfluidic chip for high-throughput antibiotic susceptibility testing of bacteria.
    Analytical and bioanalytical chemistry, 2021, Volume: 413, Issue:4

    Topics: Ampicillin; Anti-Bacterial Agents; Drug Resistance, Bacterial; Equipment Design; High-Throughput Scr

2021
Fluoroquinolone susceptibility testing of Salmonella enterica: detection of acquired resistance and selection of zone diameter breakpoints for levofloxacin and ofloxacin.
    Journal of clinical microbiology, 2014, Volume: 52, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Mi

2014
Prevalence and detection of antibiotic-resistant determinant in Salmonella isolated from food-producing animals.
    Tropical animal health and production, 2015, Volume: 47, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Cattle; Cephalothin; Chloramphenicol; Ciprofloxacin; Drug Resistance

2015
Development of a Pefloxacin Disk Diffusion Method for Detection of Fluoroquinolone-Resistant Salmonella enterica.
    Journal of clinical microbiology, 2015, Volume: 53, Issue:11

    Topics: Anti-Bacterial Agents; Bacteremia; Base Sequence; Ciprofloxacin; Disk Diffusion Antimicrobial Tests;

2015
[Primary Salmonella vascular graft infection and conservative treatment].
    Medecine et maladies infectieuses, 2008, Volume: 38, Issue:12

    Topics: Aged; Amikacin; Anti-Bacterial Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Blood Vessel Pr

2008
Spondylodiscitis due to Sallmonela in an immunocompetent patient.
    Medicinski arhiv, 2011, Volume: 65, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Discitis; Humans; Immunocompetence; Levofloxacin; Lumbar Vertebrae; Ma

2011
Salmonella Colindale osteomyelitis in an immunocompetent female patient.
    Medecine et maladies infectieuses, 2012, Volume: 42, Issue:1

    Topics: Abscess; Adolescent; Anti-Bacterial Agents; Bacterial Typing Techniques; Ceftriaxone; Combined Modal

2012
Epididymo-orchitis: an unusual manifestation of salmonellosis.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2012, Volume: 45, Issue:4

    Topics: Abscess; Administration, Intravenous; Administration, Oral; Ceftriaxone; Ciprofloxacin; Developing C

2012
Salmonella pelvic osteomyelitis in an immunocompetent child.
    BMJ case reports, 2011, May-12, Volume: 2011

    Topics: Anti-Bacterial Agents; Child; Humans; Immunocompetence; Magnetic Resonance Imaging; Male; Ofloxacin;

2011
Granulomatous osteomyelitis caused by bacteria other than mycobacteria: a report of two cases.
    Pathology, 2002, Volume: 34, Issue:5

    Topics: Adult; Ampicillin; Anti-Infective Agents; Ciprofloxacin; Female; Granuloma; Humans; Male; Middle Age

2002
Prolonged survival of an elderly woman with Salmonella dublin aortitis and conservative treatment.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:9

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Aortic Aneurysm, Thoracic; Aortitis; Ciprofloxacin;

2003
Salmonella osteomyelitis in an otherwise healthy adult male-successful management with conservative treatment: a case report.
    Journal of orthopaedic surgery (Hong Kong), 2003, Volume: 11, Issue:2

    Topics: Adult; Anti-Infective Agents; Ceftazidime; Femur; Humans; Magnetic Resonance Imaging; Male; Ofloxaci

2003
A rare cause of pericarditis.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2003, Volume: 9, Issue:12

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; HIV Infections; HIV-1; Humans;

2003
Demonstration of persistence of Salmonella typhimurium in an AIDS patient by molecular methods.
    Journal of clinical microbiology, 1994, Volume: 32, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Bacteriophage Typing; Bacteriuria; Diarrhea; DNA Trans

1994
[Ofloxacin treatment of salmonella infections].
    Mikrobiyoloji bulteni, 1993, Volume: 27, Issue:3

    Topics: Carrier State; Humans; Ofloxacin; Paratyphoid Fever; Salmonella Food Poisoning; Salmonella Infection

1993
Treatment of experimental endocarditis due to ampicillin-susceptible or ampicillin-resistant Salmonella enteritidis.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:7

    Topics: Ampicillin; Ampicillin Resistance; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime

1996
In vitro susceptibility of multiple drug resistant Salmonella typhimurium to newer fluroquinolone derivatives.
    Indian journal of pathology & microbiology, 1995, Volume: 38, Issue:4

    Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea, Infantile; Drug Resistance, Multiple; Humans; In Vit

1995
Peripheral ulcerative keratitis after Salmonella gastroenteritis.
    Cornea, 1998, Volume: 17, Issue:6

    Topics: Aged; Cornea; Corneal Neovascularization; Corneal Ulcer; Cyclopentolate; Drug Therapy, Combination;

1998
Endocarditis due to Salmonella.
    Southern medical journal, 2001, Volume: 94, Issue:4

    Topics: Aged; Anti-Infective Agents; Cardiac Catheterization; Ceftriaxone; Cephalosporins; Combined Modality

2001
Eradicative effect of cotrimoxazole and quinolones on non-typhoid salmonellae.
    Bratislavske lekarske listy, 2001, Volume: 102, Issue:8

    Topics: Anti-Bacterial Agents; Female; Humans; Male; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Ret

2001
Endotoxin release after antibiotic treatment and its potential pathogenetic role in coagulative disorders of patients with gram-negative sepsis.
    Journal of chemotherapy (Florence, Italy), 1991, Volume: 3 Suppl 1

    Topics: Anti-Infective Agents; Blood Coagulation Disorders; Endotoxins; Humans; Norfloxacin; Ofloxacin; Salm

1991
[Ofloxacin in the treatment of infection caused by Salmonella paratyphi A].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1991, Volume: 65, Issue:10

    Topics: Adult; Humans; Male; Ofloxacin; Salmonella Infections; Salmonella paratyphi A

1991
[Treatment of salmonellosis and shigellosis with the new quinolones].
    Pathologie-biologie, 1990, Volume: 38, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Ciprofloxacin; Dysentery, Bacillary; Female; Huma

1990
Successful treatment of chronic Salmonella excretor with ofloxacin.
    Lancet (London, England), 1986, May-24, Volume: 1, Issue:8491

    Topics: Adult; Anti-Infective Agents; Carrier State; Chronic Disease; Humans; Male; Ofloxacin; Oxazines; Sal

1986