ofloxacin has been researched along with Herpes Simplex in 2 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Herpes Simplex: A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antiviral activity of ofloxacin, a new quinolone derivative, against vaccinia virus (VV), herpes simplex virus (HSV) and influenza virus (InfV) was evaluated in both in vitro and in vivo experiments." | 3.67 | Antiviral activity and inhibition of topoisomerase by ofloxacin, a new quinolone derivative. ( Ikeda, S; Nishimura, C; Yazawa, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jain, AK | 1 |
| Sukhija, J | 1 |
| Chopra, I | 1 |
| Sachdev, N | 1 |
| Ikeda, S | 1 |
| Yazawa, M | 1 |
| Nishimura, C | 1 |
2 other studies available for ofloxacin and Herpes Simplex
| Article | Year |
|---|---|
Primary conjunctival herpetic geographic ulcer in an immunocompetent patient.
Topics: Acyclovir; Adult; Anti-Infective Agents; Antiviral Agents; Conjunctivitis, Viral; Herpes Simplex; Hu | 2007 |
Antiviral activity and inhibition of topoisomerase by ofloxacin, a new quinolone derivative.
Topics: Animals; Anti-Infective Agents; Cell Line; Female; Herpes Simplex; Humans; Mice; Ofloxacin; Orthomyx | 1987 |