Page last updated: 2024-11-01

ofloxacin and Hepatopulmonary Syndrome

ofloxacin has been researched along with Hepatopulmonary Syndrome in 1 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Hepatopulmonary Syndrome: A syndrome characterized by the clinical triad of advanced chronic liver disease, pulmonary vascular dilatations, and reduced arterial oxygenation (HYPOXEMIA) in the absence of intrinsic cardiopulmonary disease. This syndrome is common in the patients with LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL).

Research Excerpts

ExcerptRelevanceReference
"To study the protective effects of ofloxacin by reduction of endotoxin on lung in rats with hepatopulmonary syndrome (HPS)."3.74[Reduction of endotoxin may protect lung from injury in rats with hepatopulmonary syndrome]. ( Jia, CK; Liang, L; Wang, WB, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, WB1
Jia, CK1
Liang, L1

Other Studies

1 other study available for ofloxacin and Hepatopulmonary Syndrome

ArticleYear
[Reduction of endotoxin may protect lung from injury in rats with hepatopulmonary syndrome].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2007, Volume: 36, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Endotoxins; Hepatopulmonary Syndrome;

2007