Page last updated: 2024-11-01

ofloxacin and Hepatitis

ofloxacin has been researched along with Hepatitis in 5 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Hepatitis: INFLAMMATION of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"We report a case of lethal hepatitis possibly/probably associated with levofloxacin, doxy-cycline, and naproxen in a patient with acute M pneumoniae infection."7.75Fatal acute hepatitis after sequential treatment with levofloxacin, doxycycline, and naproxen in a patient presenting with acute Mycoplasma pneumoniae infection. ( Andrade, RJ; Carrascosa, MF; Caviedes, JR; Lavín, AC; Lucena, MI; Mones, JC; Rivero, AP; Serrano, VB, 2009)
"The authors report a case of severe BCG hepatitis resistant to tuberculostatic therapy and treated with ofloxacin."7.71[Can ofloxacin constitute an alternative antitubercular treatment for BCG hepatitis?]. ( Debois, H; Fendler, JP; Kepenekian, G; Mége, JL, 2002)
"We report a case of lethal hepatitis possibly/probably associated with levofloxacin, doxy-cycline, and naproxen in a patient with acute M pneumoniae infection."3.75Fatal acute hepatitis after sequential treatment with levofloxacin, doxycycline, and naproxen in a patient presenting with acute Mycoplasma pneumoniae infection. ( Andrade, RJ; Carrascosa, MF; Caviedes, JR; Lavín, AC; Lucena, MI; Mones, JC; Rivero, AP; Serrano, VB, 2009)
"The authors report a case of severe BCG hepatitis resistant to tuberculostatic therapy and treated with ofloxacin."3.71[Can ofloxacin constitute an alternative antitubercular treatment for BCG hepatitis?]. ( Debois, H; Fendler, JP; Kepenekian, G; Mége, JL, 2002)
"One hundred and seventy-eight cases of typhoid patients were studied on clinical and bacteriological aspects."1.30[Clinical and laboratory studies with typhoid fever 178 patients]. ( Ji, B; Lu, M; Ouyang, K, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sokolova, GB1
Kirtaeva, OV1
Lazareva, IaV1
Tsybanev, AA1
Carrascosa, MF1
Lucena, MI1
Andrade, RJ1
Caviedes, JR1
Lavín, AC1
Mones, JC1
Rivero, AP1
Serrano, VB1
Benbrika, S1
Boukari, L1
Stirnemann, J1
Letellier, E1
Fain, O1
Thomas, M1
Kettaneh, A1
Lu, M1
Ji, B1
Ouyang, K1
Fendler, JP1
Debois, H1
Mége, JL1
Kepenekian, G1

Trials

1 trial available for ofloxacin and Hepatitis

ArticleYear
[Floracide, a Russian 3rd generation fluoroquinolone in complex therapy of tuberculosis].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2008, Volume: 53, Issue:5-6

    Topics: Adult; Antitubercular Agents; Arthralgia; Diarrhea; Drug Resistance, Multiple, Bacterial; Drug Thera

2008

Other Studies

4 other studies available for ofloxacin and Hepatitis

ArticleYear
Fatal acute hepatitis after sequential treatment with levofloxacin, doxycycline, and naproxen in a patient presenting with acute Mycoplasma pneumoniae infection.
    Clinical therapeutics, 2009, Volume: 31, Issue:5

    Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Ind

2009
[A case of yersiniasis with multiple liver abscesses].
    La Revue de medecine interne, 2005, Volume: 26, Issue:2

    Topics: Diabetes Mellitus, Type 1; Drug Therapy, Combination; Hemochromatosis; Hepatitis; Humans; Imipenem;

2005
[Clinical and laboratory studies with typhoid fever 178 patients].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 1997, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Child; Female; Hepatitis; Humans; Male; Microbial Se

1997
[Can ofloxacin constitute an alternative antitubercular treatment for BCG hepatitis?].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2002, Volume: 12, Issue:2

    Topics: Aged; Anti-Infective Agents; Antitubercular Agents; Hepatitis; Humans; Male; Microbial Sensitivity T

2002