ofloxacin has been researched along with Hepatitis C, Chronic in 3 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Hepatitis C, Chronic: INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A controlled trial comparing combination therapy with ofloxacin (OFLX) and interferon (IFN) versus IFN monotherapy was conducted in patients with chronic hepatitis C who failed IFN therapy." | 9.08 | Pilot study of ofloxacin and interferon-alpha combination therapy for chronic hepatitis C without sustained response to initial interferon administration. ( Chiba, M; Fujii, T; Goto, T; Hoshino, T; Ishii, T; Komatsu, M; Kuramitsu, T; Masamune, O; Ono, T; Toyoshima, I, 1997) |
| "Ofloxacin, a quinolone antibiotic, was recently shown to increase the primary response rate to alpha-interferon treatment of chronic hepatitis C." | 9.08 | Treatment of chronic hepatitis C with alpha-interferon plus ofloxacin in patients not responding to alpha-interferon alone. ( Giostra, E; Hadengue, A; Male, PJ; Negro, F; Perrin, L, 1998) |
| "A controlled trial comparing combination therapy with ofloxacin (OFLX) and interferon (IFN) versus IFN monotherapy was conducted in patients with chronic hepatitis C who failed IFN therapy." | 5.08 | Pilot study of ofloxacin and interferon-alpha combination therapy for chronic hepatitis C without sustained response to initial interferon administration. ( Chiba, M; Fujii, T; Goto, T; Hoshino, T; Ishii, T; Komatsu, M; Kuramitsu, T; Masamune, O; Ono, T; Toyoshima, I, 1997) |
| "Ofloxacin, a quinolone antibiotic, was recently shown to increase the primary response rate to alpha-interferon treatment of chronic hepatitis C." | 5.08 | Treatment of chronic hepatitis C with alpha-interferon plus ofloxacin in patients not responding to alpha-interferon alone. ( Giostra, E; Hadengue, A; Male, PJ; Negro, F; Perrin, L, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guettrot-Imbert, G | 1 |
| Letranchant, L | 1 |
| Gallot, D | 1 |
| Romaszko, C | 1 |
| Laurichesse, H | 1 |
| Komatsu, M | 1 |
| Ishii, T | 1 |
| Ono, T | 1 |
| Hoshino, T | 1 |
| Kuramitsu, T | 1 |
| Goto, T | 1 |
| Fujii, T | 1 |
| Toyoshima, I | 1 |
| Chiba, M | 1 |
| Masamune, O | 1 |
| Negro, F | 1 |
| Male, PJ | 1 |
| Perrin, L | 1 |
| Giostra, E | 1 |
| Hadengue, A | 1 |
2 trials available for ofloxacin and Hepatitis C, Chronic
| Article | Year |
|---|---|
Pilot study of ofloxacin and interferon-alpha combination therapy for chronic hepatitis C without sustained response to initial interferon administration.
Topics: Adult; Alanine Transaminase; Anti-Infective Agents; Drug Therapy, Combination; Female; Hepacivirus; | 1997 |
Treatment of chronic hepatitis C with alpha-interferon plus ofloxacin in patients not responding to alpha-interferon alone.
Topics: Adult; Anti-Infective Agents; Antiviral Agents; Drug Therapy, Combination; Female; Follow-Up Studies | 1998 |
1 other study available for ofloxacin and Hepatitis C, Chronic
| Article | Year |
|---|---|
[Multiorgan failure due to gonococcal peritonitis in an HIV-HCV co-infected female patient].
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Ascites; Bacteremia; Carcinoma, Hepatocellular | 2004 |