ofloxacin has been researched along with Hepatic Insufficiency in 2 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Hepatic Insufficiency: Conditions in which the LIVER functions fall below the normal ranges. Severe hepatic insufficiency may cause LIVER FAILURE or DEATH. Treatment may include LIVER TRANSPLANTATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zueva, LB | 1 |
| Ho, CC | 1 |
| Chen, YC | 1 |
| Hu, FC | 1 |
| Yu, CJ | 1 |
| Yang, PC | 1 |
| Luh, KT | 1 |
1 trial available for ofloxacin and Hepatic Insufficiency
| Article | Year |
|---|---|
[Zoflox, an antibacterial drug, in treatment of infectious pathologic processes in the lower respiratory tract complicating acute respiratory viral infection in elderly patients].
Topics: Acute Disease; Aged; Ambulatory Care; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Femal | 2012 |
1 other study available for ofloxacin and Hepatic Insufficiency
| Article | Year |
|---|---|
Safety of fluoroquinolone use in patients with hepatotoxicity induced by anti-tuberculosis regimens.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anti-Bacterial Agents; Antitubercu | 2009 |