Page last updated: 2024-11-01

ofloxacin and Heart Diseases

ofloxacin has been researched along with Heart Diseases in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.

Research Excerpts

ExcerptRelevanceReference
"Levofloxacin has a very low phototoxicity-inducing potential confirmed by pre-clinical animal studies and the results of post-marketing surveillance (PMS)."2.41Latest industry information on the safety profile of levofloxacin in Japan. ( Yagawa, K, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saraçoğlu, A1
Temel, HE1
Ergun, B1
Colak, O1
Yagawa, K1

Reviews

1 review available for ofloxacin and Heart Diseases

ArticleYear
Latest industry information on the safety profile of levofloxacin in Japan.
    Chemotherapy, 2001, Volume: 47 Suppl 3

    Topics: Adverse Drug Reaction Reporting Systems; Anti-Infective Agents; Central Nervous System; Chemical and

2001

Other Studies

1 other study available for ofloxacin and Heart Diseases

ArticleYear
Oxidative stress-mediated myocardiotoxicity of ciprofloxacin and ofloxacin in juvenile rats.
    Drug and chemical toxicology, 2009, Volume: 32, Issue:3

    Topics: Animals; Anti-Infective Agents; Biomarkers; Ciprofloxacin; Heart; Heart Diseases; Malondialdehyde; M

2009