Page last updated: 2024-11-01

ofloxacin and Group A Strep Infection

ofloxacin has been researched along with Group A Strep Infection in 56 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"The objective of this open-label, single-arm, multicenter study was to assess the efficacy and safety of levofloxacin in the treatment of complicated urinary tract infections."9.10[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections]. ( Marchetti, F; Trinchieri, A, 2003)
"Endogenous endophthalmitis is a rare complication of infective endocarditis and has been decreasing due to the availability of effective antibiotics."5.35Levofloxacin-resistant-Streptococcus mitis endophthalmitis: a unique presentation of bacterial endocarditis. ( Dinani, A; Ktaich, N; Rubin, D; Urban, C, 2009)
"The objective of this open-label, single-arm, multicenter study was to assess the efficacy and safety of levofloxacin in the treatment of complicated urinary tract infections."5.10[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections]. ( Marchetti, F; Trinchieri, A, 2003)
" In a prospective, randomized, open trial, we evaluated the efficacy and safety of oral roxithromycin (150 mg twice daily) as additional antibacterial prophylaxis in 131 adult patients with acute leukemia and bone marrow transplant recipients receiving oral ofloxacin."5.07A randomized trial of roxithromycin in patients with acute leukemia and bone marrow transplant recipients receiving fluoroquinolone prophylaxis. ( Arnold, R; Hay, B; Kern, P; Kern, WV; Marre, R, 1994)
"Ofloxacine (Tarivid-Hoechst) was used in 30 patients with infections of the respiratory system, including 12 with pneumonias, 18 with chronic bronchitis."3.68[Evaluation of the effectiveness of ofloxacin in the treatment of respiratory tract]. ( Chyrek-Borowska, S; Jakubicz, P; Siergiejko, Z, 1991)
" In contrast, a small number of levofloxacin-resistant streptococci were observed at the end of dosing but decreased by week 2 post-dosing and continued to decrease through the 6-week evaluation period (p < 0."2.74Levofloxacin versus azithromycin on the oropharyngeal carriage and selection of antibacterial- resistant streptococci in the microflora of healthy adults. ( Ambruzs, M; Fisher, AC; Nord, CE; Peterson, J, 2009)
" Drug-related adverse events were reported by 8."2.69A multicentre, double-blind, randomised study comparing the efficacy and safety of oral levofloxacin versus ciprofloxacin in the treatment of uncomplicated skin and skin structure infections. ( Jasovich, A; Neto, W; Nicodemo, AC; Robledo, JA, 1998)
"Ofloxacin was administered at a dose of 200 mg every 12 hours for a mean duration of ten days."2.66[Efficacy of injectable ofloxacin in treating septicemia. Multicenter study]. ( Doco-Lecompte, T; Modaï, J, 1989)
"We present a case of septic arthritis of the TMJ following the extraction of the left upper second molar that occurred 1 week before beginning of symptoms."2.44Septic arthritis of the temporomandibular joint successfully treated with arthroscopic lysis and lavage: case report and review of the literature. ( Albiero, AM; Costa, F; Politi, M; Robiony, M; Sembronio, S; Toro, C, 2007)
" Pharmacodynamic principles can also be used to devise the optimal administration regimen for specific antimicrobial agents."2.41Pharmacodynamics and pharmacokinetics of levofloxacin. ( Grant, EM; Nightingale, CH; Quintiliani, R, 2000)
" FQs at proper dosage can be effective against S."1.39Effect of subinhibitory concentrations of fluoroquinolones on biofilm production by clinical isolates of Streptococcus pyogenes. ( Balaji, K; Pandian, SK; Thenmozhi, R, 2013)
"Endogenous endophthalmitis is a rare complication of infective endocarditis and has been decreasing due to the availability of effective antibiotics."1.35Levofloxacin-resistant-Streptococcus mitis endophthalmitis: a unique presentation of bacterial endocarditis. ( Dinani, A; Ktaich, N; Rubin, D; Urban, C, 2009)
"We present the case of a patient with ADPKD and suspected cyst infection caused by group B streptococcus who was treated successfully with levofloxacin and ampicillin."1.33Levofloxacin penetration into a renal cyst in a patient with autosomal dominant polycystic kidney disease. ( Hiyama, L; Miller, LG; Tang, A, 2006)
"Levofloxacin was also quite active, inhibiting 98-100% of the isolates at concentrations < or = 2 micrograms/ml."1.30Comparative antistreptococcal activity of two newer fluoroquinolones, levofloxacin and sparfloxacin. ( Jones, RN; Pfaller, MA, 1997)
"HSR-903 was active against experimental respiratory tract infections in mice challenged with penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae and Haemophilus influenzae strains."1.30In vivo activity of HSR-903, a new fluoroquinolone, against respiratory pathogens. ( Domon, H; Miyazaki, S; Yamaguchi, K; Yoshizumi, S, 1998)
"Levofloxacin was no more effective than penicillin against the penicillin-resistant strain."1.30Efficacy of levofloxacin for experimental aortic-valve endocarditis in rabbits infected with viridans group streptococcus or Staphylococcus aureus. ( Chambers, HF; Chow, LL; Hackbarth, C; Xiang, Q, 1999)
"Levofloxacin was investigated against viridans group streptococci in vitro and in rats with experimental aortic endocarditis."1.30Efficacy of levofloxacin in the treatment of experimental endocarditis caused by viridans group streptococci. ( Caldelari, I; Entenza, JM; Glauser, MP; Moreillon, P, 1999)
"Against respiratory tract infections with K."1.28In vivo evaluation of NM441, a new thiazeto-quinoline derivative. ( Kimura, K; Kise, M; Kitano, M; Matsuda, M; Nishino, T; Otsuki, M; Ozaki, M; Segawa, J; Shibata, K; Tomii, Y, 1991)
"Ofloxacin was active against all but one (Pseudomonas aeruginosa) blood culture isolates."1.27Comparative activity of ofloxacin with reference to bacterial strains isolated in in-patients and out-patients. ( Alkan, M; Berger, S; Bogokowski, B; Keren, G; Mark, Z; Rubinstein, E, 1986)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19903 (5.36)18.7374
1990's18 (32.14)18.2507
2000's25 (44.64)29.6817
2010's10 (17.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyamoto, T1
Matsumoto, J1
Chiba, K1
Egawa, H1
Shibamori, K1
Minamida, A1
Nishimura, Y1
Okada, H1
Kataoka, M1
Fujita, M1
Montes, M1
Tamayo, E1
Orden, B1
Larruskain, J1
Perez-Trallero, E1
Chan, E1
Ayres, M1
Balaji, K1
Thenmozhi, R1
Pandian, SK1
O'Connor, KM1
Williams, P1
Pergam, SA1
Wajima, T1
Murayama, SY1
Sunaoshi, K1
Nakayama, E1
Sunakawa, K1
Ubukata, K1
Gracia, M1
Díaz, C1
Coronel, P1
Gimeno, M1
García-Rodas, R1
Rodríguez-Cerrato, V1
del Prado, G1
Huelves, L1
Ruiz, V1
Naves, PF1
Ponte, MC1
Granizo, JJ1
Soriano, F1
Aggarwal, H1
Smith, AD1
Kuo, PC1
Vikraman, DS1
Nord, CE1
Peterson, J1
Ambruzs, M1
Fisher, AC1
Dinani, A1
Ktaich, N1
Urban, C1
Rubin, D1
Llaneza, E1
Seral, C1
Castillo, FJ1
Durán, E1
Rubio-Calvo, C1
Gómez-Lus, R1
Köller, T1
Manetti, AGO1
Kreikemeyer, B1
Lembke, C1
Margarit, I1
Grandi, G1
Podbielski, A1
Orr, D1
Wilkinson, P1
Moyce, L1
Martin, S1
George, R1
Pichon, B1
Pinho, MD1
Melo-Cristino, J1
Ramirez, M1
Salman, S1
Young, M1
Van Sickels, JE1
Lorenzo Garde, L1
Bolaños Rivero, M1
Turégano García, Á1
Martín Sánchez, AM1
Treszezamsky, AD1
Feldman, D1
Sarabanchong, VO1
Wang, H1
Zhao, C1
He, W1
Zhang, F1
Zhang, L1
Cao, B1
Sun, Z1
Xu, Y1
Yang, Q1
Mei, Y1
Hu, B1
Chu, Y1
Liao, K1
Yu, Y1
Hu, Z1
Ni, Y1
Richter, SS1
Diekema, DJ1
Heilmann, KP1
Almer, LS1
Shortridge, VD1
Zeitler, R1
Flamm, RK1
Doern, GV1
Trinchieri, A1
Marchetti, F1
Rodríguez-Zurita, ME1
Solís del Baño, S1
Robres Guillén, P1
González Praetorius, A1
Gimeno Fernández, C1
Pérez Pomata, MT1
Bisquert Santiago, J1
Mulla, ZD1
Entenza, JM2
Vouillamoz, J1
Glauser, MP2
Moreillon, P2
Barequet, IS1
Denton, P1
Osterhout, GJ1
Tuli, S1
O'Brien, TP1
Reinert, RR1
Lütticken, R1
Al-Lahham, A1
Bloom, C1
Thomson, EC1
Main, J1
Rivera, A1
Rebollo, M1
Sánchez, F1
Navarro, F1
Miró, E1
Mirelis, B1
Coll, P1
Hiyama, L1
Tang, A1
Miller, LG1
Sembronio, S1
Albiero, AM1
Robiony, M1
Costa, F1
Toro, C1
Politi, M1
Mollerach, A1
Méndez, E1
Massa, R1
Di Conza, J1
Alonso, R1
Mateo, E1
Ezpeleta, G1
Cisterna, R1
Tazi, A1
Gueudet, T1
Varon, E1
Gilly, L1
Trieu-Cuot, P1
Poyart, C1
Brook, I2
Tom, SP1
Ledney, GD2
Kern, WV1
Hay, B1
Kern, P1
Marre, R1
Arnold, R1
Bow, EJ1
Mandell, LA1
Louie, TJ1
Feld, R1
Palmer, M1
Zee, B1
Pater, J1
Plouffe, JF1
Spanik, S1
Trupl, J1
Kunova, A1
Botek, R1
Sorkovska, D1
Grey, E1
Studena, M1
Lacka, J1
Oravcova, E1
Krchnakova, A1
Rusnakova, V1
Svec, J1
Krupova, I1
Grausova, S1
Stopkova, K1
Koren, P1
Krcmery, V2
Pfaller, MA1
Jones, RN1
Tuohy, M1
Washington, JA1
Yoshizumi, S1
Domon, H1
Miyazaki, S1
Yamaguchi, K1
Nicodemo, AC1
Robledo, JA1
Jasovich, A1
Neto, W1
Akiyama, H1
Yamasaki, O1
Kanzaki, H1
Tada, J1
Arata, J1
Krupova, Y1
Novotny, J1
Sabo, A1
Mateicka, F1
Prenna, M1
Montanari, MP1
Mingoia, M1
Biavasco, F1
Ripa, S1
Varaldo, PE1
Chambers, HF1
Xiang, Q1
Chow, LL1
Hackbarth, C1
Caldelari, I1
Nightingale, CH1
Grant, EM1
Quintiliani, R1
Lin, FY1
Azimi, PH1
Weisman, LE1
Philips, JB1
Regan, J1
Clark, P1
Rhoads, GG1
Clemens, J1
Troendle, J1
Pratt, E1
Brenner, RA1
Gill, V1
Remacha Esteras, M1
Herrera Rubio, J1
Parra Parra, I1
Rodríguez-Avial, I1
Rodríguez-Avial, C1
Picazo, JJ1
Ozaki, M1
Matsuda, M1
Tomii, Y1
Kimura, K1
Segawa, J1
Kitano, M1
Kise, M1
Shibata, K1
Otsuki, M1
Nishino, T1
Chyrek-Borowska, S1
Siergiejko, Z1
Jakubicz, P1
Doco-Lecompte, T1
Modaï, J1
Sugimoto, R1
Satoh, T1
Rubinstein, E1
Mark, Z1
Keren, G1
Alkan, M1
Berger, S1
Bogokowski, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Open-Label Study Comparing Levofloxacin Once-Daily 750 mg PO for 5 Days and Azithromycin Once-Daily 500 mg on Day One and Then 250 mg Days 2 Through 5 In a Microbiologic Evaluation for Emergence of Resistance in the Oropharyngeal Flora of He[NCT00821782]Phase 1143 participants (Actual)Interventional2006-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ofloxacin and Group A Strep Infection

ArticleYear
Septic arthritis of the temporomandibular joint successfully treated with arthroscopic lysis and lavage: case report and review of the literature.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007, Volume: 103, Issue:2

    Topics: Amoxicillin; Anti-Bacterial Agents; Arthritis, Infectious; Arthroscopy; Drainage; Female; Humans; Mi

2007
Pharmacodynamics and pharmacokinetics of levofloxacin.
    Chemotherapy, 2000, Volume: 46 Suppl 1

    Topics: Anti-Infective Agents; Area Under Curve; Cost-Benefit Analysis; Cross Infection; Drug Costs; Humans;

2000

Trials

6 trials available for ofloxacin and Group A Strep Infection

ArticleYear
Levofloxacin versus azithromycin on the oropharyngeal carriage and selection of antibacterial- resistant streptococci in the microflora of healthy adults.
    Current medical research and opinion, 2009, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Dose-Response Relationship, Drug; Drug Resis

2009
[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2003, Volume: 75, Issue:1

    Topics: Anti-Infective Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Enterobacteriaceae

2003
A randomized trial of roxithromycin in patients with acute leukemia and bone marrow transplant recipients receiving fluoroquinolone prophylaxis.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Bone Marrow Transplantation; Cyclospo

1994
Quinolone-based antibacterial chemoprophylaxis in neutropenic patients: effect of augmented gram-positive activity on infectious morbidity. National Cancer Institute of Canada Clinical Trials Group.
    Annals of internal medicine, 1996, Aug-01, Volume: 125, Issue:3

    Topics: Adult; Aged; Anti-Infective Agents; Antineoplastic Agents; Bacteremia; Colony Count, Microbial; Fema

1996
A multicentre, double-blind, randomised study comparing the efficacy and safety of oral levofloxacin versus ciprofloxacin in the treatment of uncomplicated skin and skin structure infections.
    International journal of clinical practice, 1998, Volume: 52, Issue:2

    Topics: Administration, Oral; Adult; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Female; Huma

1998
[Efficacy of injectable ofloxacin in treating septicemia. Multicenter study].
    Pathologie-biologie, 1989, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Gram-Negative Bacteria; Humans; Injections, Intr

1989

Other Studies

48 other studies available for ofloxacin and Group A Strep Infection

ArticleYear
Synthesis and structure-activity relationships of 5-substituted 6,8-difluoroquinolones, including sparfloxacin, a new quinolone antibacterial agent with improved potency.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:6

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; Drug Interactions; Fluoroquinolones; Male; Mice; Micro

1990
Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Child; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genes, Ba

2010
Corneal Perforation With Iris Plugging.
    JAMA ophthalmology, 2018, 03-08, Volume: 136, Issue:3

    Topics: Anti-Bacterial Agents; Corneal Perforation; Cyanoacrylates; Eye Infections, Bacterial; Humans; Iris

2018
Effect of subinhibitory concentrations of fluoroquinolones on biofilm production by clinical isolates of Streptococcus pyogenes.
    The Indian journal of medical research, 2013, Volume: 137, Issue:5

    Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Se

2013
An unusual case of knee pain: pseudogout and Abiotrophia defectiva infection.
    Southern medical journal, 2008, Volume: 101, Issue:9

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Infectious; Calcium Pyrophosphate; Ceftriaxone;

2008
Distribution of emm type and antibiotic susceptibility of group A streptococci causing invasive and noninvasive disease.
    Journal of medical microbiology, 2008, Volume: 57, Issue:Pt 11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, Bacterial; Bacterial Outer Membrane Proteins;

2008
Antimicrobial susceptibility of Streptococcus pyogenes in Central, Eastern, and Baltic European Countries, 2005 to 2006: the cefditoren surveillance program.
    Diagnostic microbiology and infectious disease, 2009, Volume: 64, Issue:1

    Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Child; Drug Resistance, Bacterial; Europe; Female; Human

2009
Streptococcus equi primary bacteremia in a hepatitis-C cirrhotic patient.
    Transplantation, 2009, Mar-15, Volume: 87, Issue:5

    Topics: Anti-Bacterial Agents; Bacteremia; Hepatitis C; Humans; Liver Cirrhosis; Male; Middle Aged; Ofloxaci

2009
Levofloxacin-resistant-Streptococcus mitis endophthalmitis: a unique presentation of bacterial endocarditis.
    Journal of medical microbiology, 2009, Volume: 58, Issue:Pt 10

    Topics: Aged; Aged, 80 and over; Drug Resistance, Bacterial; Echocardiography; Endocarditis, Subacute Bacter

2009
Characterization of clinical blood isolates of Streptococcus agalactiae with reduced susceptibility to levofloxacin.
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:4

    Topics: Agglutination Tests; Anti-Bacterial Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Oflox

2009
Typing of the pilus-protein-encoding FCT region and biofilm formation as novel parameters in epidemiological investigations of Streptococcus pyogenes isolates from various infection sites.
    Journal of medical microbiology, 2010, Volume: 59, Issue:Pt 4

    Topics: Bacterial Typing Techniques; Biofilms; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Fiel

2010
Incidence and epidemiology of levofloxacin resistance in Streptococcus pneumoniae: experience from a tertiary referral hospital in England.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; bet

2010
Fluoroquinolone resistance in Streptococcus dysgalactiae subsp. equisimilis and evidence for a shared global gene pool with Streptococcus pyogenes.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Amino Acid Substitution; Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, B

2010
Osteomyelitis after bilateral sagittal split osteotomy: case report and a review of the management.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2011, Volume: 111, Issue:4

    Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Bone Plates; Bone Screws; Clindamycin; Drainage; Enterob

2011
[Intraperitoneal abscess for Eikenella corrodens].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2011, Volume: 24, Issue:2

    Topics: Abdominal Abscess; Adenocarcinoma; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacteri

2011
Concurrent postpartum uterine and abdominal wall dehiscence and Streptococcus anginosus infection.
    Obstetrics and gynecology, 2011, Volume: 118, Issue:2 Pt 2

    Topics: Abdominal Wall; Acute Disease; Adolescent; Anti-Bacterial Agents; Ascitic Fluid; Cefazolin; Cesarean

2011
High prevalence of fluoroquinolone-resistant group B streptococci among clinical isolates in China and predominance of sequence type 19 with serotype III.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; China; Clindamycin; DNA Gyrase; DNA Topoisomerase IV

2013
Fluoroquinolone resistance in Streptococcus pyogenes.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Feb-01, Volume: 36, Issue:3

    Topics: Amino Acid Substitution; Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, B

2003
[Susceptibility of Streptococcus pyogenes to macrolides and quinolones in Guadalajara, Spain].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2003, Volume: 16, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clindamycin; Drug Resistance, Bacterial; Erythromycin;

2003
Group A streptococcal pneumonia.
    Archives of internal medicine, 2003, Sep-22, Volume: 163, Issue:17

    Topics: Anti-Infective Agents; Florida; Humans; Ofloxacin; Streptococcal Infections; Streptococcus pyogenes

2003
Efficacy of garenoxacin in treatment of experimental endocarditis due to Staphylococcus aureus or viridans group streptococci.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; En

2004
Treatment of experimental bacterial keratitis with topical trovafloxacin.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2004, Volume: 122, Issue:1

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Biological Availability; Ciprofloxacin; Col

2004
High-level fluoroquinolone resistance in a clinical Streptoccoccus pyogenes isolate in Germany.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2004, Volume: 10, Issue:7

    Topics: Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroq

2004
An elderly lady with sudden blindness and a sore foot.
    The Journal of infection, 2006, Volume: 52, Issue:2

    Topics: Administration, Topical; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Blindness; Ceftriaxon

2006
Characterisation of fluoroquinolone-resistant clinical isolates of Streptococcus pyogenes in Barcelona, Spain.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2005, Volume: 11, Issue:9

    Topics: Amino Acid Substitution; Anti-Infective Agents; Antigens, Bacterial; Bacterial Outer Membrane Protei

2005
Levofloxacin penetration into a renal cyst in a patient with autosomal dominant polycystic kidney disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 47, Issue:1

    Topics: Adult; Ampicillin; Anti-Bacterial Agents; Biological Availability; Drug Therapy, Combination; Female

2006
[Streptococcus agalactiae isolated in Santa Fe, Argentina: antibiotic susceptibility and erythromycin-clindamycin resistance mechanisms].
    Enfermedades infecciosas y microbiologia clinica, 2007, Volume: 25, Issue:1

    Topics: Ampicillin; Argentina; Bacterial Proteins; Clindamycin; Drug Resistance, Multiple, Bacterial; Erythr

2007
Characterisation of levofloxacin-resistant clinical isolates of Streptococcus pyogenes in Bilbao, Spain.
    International journal of antimicrobial agents, 2007, Volume: 30, Issue:2

    Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Fem

2007
Fluoroquinolone-resistant group B streptococci in acute exacerbation of chronic bronchitis.
    Emerging infectious diseases, 2008, Volume: 14, Issue:2

    Topics: Acute Disease; Aged, 80 and over; Anti-Bacterial Agents; Bronchitis; Chronic Disease; DNA Gyrase; Dr

2008
Development of infection with Streptococcus bovis and Aspergillus sp. in irradiated mice after glycopeptide therapy.
    The Journal of antimicrobial chemotherapy, 1993, Volume: 32, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Aspergillosis; Aspergillus fumigatus; Drug Resistance, Microbial; Dr

1993
Levofloxacin in vitro activity against bacteremic isolates of Streptococcus pneumoniae. Franklin County Pneumonia Study Group.
    Diagnostic microbiology and infectious disease, 1996, Volume: 25, Issue:1

    Topics: Anti-Infective Agents; Bacteremia; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin

1996
Viridans streptococcal bacteraemia due to penicillin-resistant and penicillin-sensitive streptococci: analysis of risk factors and outcome in 60 patients from a single cancer centre before and after penicillin is used for prophylaxis.
    Scandinavian journal of infectious diseases, 1997, Volume: 29, Issue:3

    Topics: Acute Disease; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremia; Dru

1997
Comparative antistreptococcal activity of two newer fluoroquinolones, levofloxacin and sparfloxacin.
    Diagnostic microbiology and infectious disease, 1997, Volume: 29, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; In Vitro

1997
Antimicrobial susceptibility of viridans group streptococci.
    Diagnostic microbiology and infectious disease, 1997, Volume: 29, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Cefazolin; Ceftriaxone; Clindamycin; Drug Resistance, Microbial;

1997
In vivo activity of HSR-903, a new fluoroquinolone, against respiratory pathogens.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:4

    Topics: Animals; Anti-Infective Agents; Area Under Curve; Fluoroquinolones; Haemophilus Infections; Haemophi

1998
Streptococci isolated from various skin lesions: the interaction with Staphylococcus aureus strains.
    Journal of dermatological science, 1999, Volume: 19, Issue:1

    Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Erythromycin; Fluoroquinol

1999
Aetiology, cost of antimicrobial therapy and outcome in neutropenic patients who developed bacteraemia during antimicrobial prophylaxis: a case-control study.
    International journal of antimicrobial agents, 1998, Volume: 10, Issue:4

    Topics: Amikacin; Amphotericin B; Antibiotic Prophylaxis; Bacteremia; Bacterial Infections; Case-Control Stu

1998
Antistaphylococcal and antistreptococcal killing kinetics of ciprofloxacin, ofloxacin, sparfloxacin, and trovafloxacin.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1998, Volume: 17, Issue:11

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbia

1998
Efficacy of levofloxacin for experimental aortic-valve endocarditis in rabbits infected with viridans group streptococcus or Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:11

    Topics: Animals; Aortic Valve; Drug Resistance, Microbial; Endocarditis, Bacterial; Heart Valve Diseases; Le

1999
Efficacy of levofloxacin in the treatment of experimental endocarditis caused by viridans group streptococci.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:6

    Topics: Animals; Anti-Infective Agents; Catheterization; Ceftriaxone; Ciprofloxacin; Endocarditis, Bacterial

1999
Antibiotic susceptibility profiles for group B streptococci isolated from neonates, 1995-1998.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 31, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Capsules; Cefotaxime; Chloramphenicol; Clindamycin; Drug Resistance

2000
[Bacteremic pneumonia due to Streptococcus equisimilis].
    Archivos de bronconeumologia, 2001, Volume: 37, Issue:8

    Topics: Aged; Anti-Infective Agents; Blood; Humans; Male; Ofloxacin; Pneumonia, Bacterial; Streptococcal Inf

2001
[In vitro activity of six fluoroquinolones and penicillin against 101 viridans group streptococci characterized by their susceptibility to erythromycin].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2001, Volume: 14, Issue:4

    Topics: Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Drug Resistance; Drug Resistance, M

2001
In vivo evaluation of NM441, a new thiazeto-quinoline derivative.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:12

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dogs; Drug Evaluati

1991
[Evaluation of the effectiveness of ofloxacin in the treatment of respiratory tract].
    Pneumonologia i alergologia polska, 1991, Volume: 59, Issue:1-2

    Topics: Administration, Oral; Adult; Aged; Bronchitis; Chronic Disease; Drug Resistance, Microbial; Enteroco

1991
Ofloxacin and penicillin G combination therapy in prevention of bacterial translocation and animal mortality after irradiation.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:8

    Topics: Animals; Drug Therapy, Combination; Enterobacteriaceae; Female; Liver; Mice; Mice, Inbred C3H; Oflox

1991
[Bone and suppurative lesion distribution of antimicrobial agents (ampicillin and ofloxacin) in experimental infected rabbits].
    Shigaku = Odontology; journal of Nihon Dental College, 1989, Volume: 76, Issue:7

    Topics: Ampicillin; Animals; Bacteroides Infections; Mandibular Diseases; Ofloxacin; Rabbits; Streptococcal

1989
Comparative activity of ofloxacin with reference to bacterial strains isolated in in-patients and out-patients.
    Infection, 1986, Volume: 14 Suppl 1

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cross Infection; Dose-Response Relationship,

1986