Page last updated: 2024-11-01

ofloxacin and Gram-Positive Bacterial Infections

ofloxacin has been researched along with Gram-Positive Bacterial Infections in 54 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Gram-Positive Bacterial Infections: Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.

Research Excerpts

ExcerptRelevanceReference
"Compare two dosage strengths of levofloxacin in the treatment of acute bacterial sinusitis."9.12A trial of high-dose, short-course levofloxacin for the treatment of acute bacterial sinusitis. ( Anon, J; Kahn, J; Khashab, M; Paglia, M; Poole, M; Xiang, J, 2006)
"A randomized, double-blind, double-dummy, three-arm parallel design, multicentre study was conducted among adult patients with acute exacerbation of chronic bronchitis (AECB) in order to compare the efficacy and safety of two different doses of levofloxacin with cefuroxime axetil."9.09Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbation of chronic bronchitis: results of a randomized, double-blind study. ( Dolmann, A; Fiss, E; Maesen, FP; Shah, PM; Vetter, N; Wesch, R, 1999)
"An open, randomized, multinational, multicentre study was conducted to compare the efficacy, safety and tolerability of levofloxacin 500 mg twice daily with imipenem/cilastatin 1 g iv three-times daily in the treatment of hospitalized adult patients with clinically suspected bacteraemia/ sepsis."9.09Levofloxacin in the empirical treatment of patients with suspected bacteraemia/sepsis: comparison with imipenem/cilastatin in an open, randomized trial. ( Geddes, A; Härkönen, M; Jacobs, F; Nowotny, I; Schonwald, S; Thaler, M, 1999)
"The purpose of this study was to assess the clinical efficacy of high-dose levofloxacin plus rifampicin in the empirical treatment of non-tuberculous spondylodiscitis in an epidemiological context of low incidence of staphylococcal fluoroquinolone resistance."7.75Treatment of pyogenic (non-tuberculous) spondylodiscitis with tailored high-dose levofloxacin plus rifampicin. ( Crapis, M; Cristini, F; Furlanut, M; Negri, C; Pavan, F; Pea, F; Scudeller, L; Viale, P; Zamparini, E; Zuiani, C, 2009)
"Thirty cirrhotic patients with spontaneous bacterial peritonitis were assigned to receive either intravenous (1 g/12 h) cefotaxime for 7 days (n=17) or intravenous (200 mg/12 h) ofloxacin for 2 days followed by oral (200 mg/12 h) ofloxacin for 5 days (n=13)."7.72Comparison of cefotaxime and ofloxacin in treatment of spontaneous bacterial peritonitis. ( Aslan, SL; Buyraç, Z; Colakoğlu, O; Sözmen, B; Taşkiran, B; Unsal, B, 2004)
"Compare two dosage strengths of levofloxacin in the treatment of acute bacterial sinusitis."5.12A trial of high-dose, short-course levofloxacin for the treatment of acute bacterial sinusitis. ( Anon, J; Kahn, J; Khashab, M; Paglia, M; Poole, M; Xiang, J, 2006)
"The objective of this multicenter, randomized, controlled, parallel group trial was to evaluate the efficacy of levofloxacin 250 mg oral, once daily (LVFX), placebo one tablet oral once daily (Placebo [P] group) and ciprofloxacin (CPFX) 500 mg oral, twice daily (single blind), prophylaxis in preventing bacteriuria (> or = 10(3) CFU/ml) in post-surgical catheterized patients."5.12A pilot study on prevention of catheter-related urinary tract infections with fluoroquinolones. ( Drago, L; Esposito, S; Leone, S; Marchetti, F; Marvaso, A; Noviello, S, 2006)
"A randomized, double-blind, double-dummy, three-arm parallel design, multicentre study was conducted among adult patients with acute exacerbation of chronic bronchitis (AECB) in order to compare the efficacy and safety of two different doses of levofloxacin with cefuroxime axetil."5.09Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbation of chronic bronchitis: results of a randomized, double-blind study. ( Dolmann, A; Fiss, E; Maesen, FP; Shah, PM; Vetter, N; Wesch, R, 1999)
"An open, randomized, multinational, multicentre study was conducted to compare the efficacy, safety and tolerability of levofloxacin 500 mg twice daily with imipenem/cilastatin 1 g iv three-times daily in the treatment of hospitalized adult patients with clinically suspected bacteraemia/ sepsis."5.09Levofloxacin in the empirical treatment of patients with suspected bacteraemia/sepsis: comparison with imipenem/cilastatin in an open, randomized trial. ( Geddes, A; Härkönen, M; Jacobs, F; Nowotny, I; Schonwald, S; Thaler, M, 1999)
"We examined Enterococcus faecalis strains clinically isolated from 100 patients with urinary tract infections (UTIs) for their susceptibility to levofloxacin (LVX) by measuring the MIC and investigated amino acid mutations by direct DNA sequencing, which were then correlated with LVX resistance."3.77Mechanisms of and risk factors for fluoroquinolone resistance in clinical Enterococcus faecalis isolates from patients with urinary tract infections. ( Arakawa, S; Fujisawa, M; Kawabata, M; Matsumoto, M; Nakano, Y; Shigemura, K; Shirakawa, T; Tanaka, K; Yasufuku, T, 2011)
"The purpose of this study was to assess the clinical efficacy of high-dose levofloxacin plus rifampicin in the empirical treatment of non-tuberculous spondylodiscitis in an epidemiological context of low incidence of staphylococcal fluoroquinolone resistance."3.75Treatment of pyogenic (non-tuberculous) spondylodiscitis with tailored high-dose levofloxacin plus rifampicin. ( Crapis, M; Cristini, F; Furlanut, M; Negri, C; Pavan, F; Pea, F; Scudeller, L; Viale, P; Zamparini, E; Zuiani, C, 2009)
"3% gatifloxacin ophthalmic solution in preventing bacterial endophthalmitis in rabbits."3.74Prophylactic efficacy of ophthalmic quinolones in experimental endophthalmitis in rabbits. ( Kozai, S; Ohashi, Y; Sakaki, H; Suzuki, T; Tajika, T; Wada, T, 2008)
"Thirty cirrhotic patients with spontaneous bacterial peritonitis were assigned to receive either intravenous (1 g/12 h) cefotaxime for 7 days (n=17) or intravenous (200 mg/12 h) ofloxacin for 2 days followed by oral (200 mg/12 h) ofloxacin for 5 days (n=13)."3.72Comparison of cefotaxime and ofloxacin in treatment of spontaneous bacterial peritonitis. ( Aslan, SL; Buyraç, Z; Colakoğlu, O; Sözmen, B; Taşkiran, B; Unsal, B, 2004)
"We report a case of bacteremia due to Abiotrophia species in a patient with neutropenic fever and cancer who was receiving levofloxacin prophylaxis, followed by empirical therapy with cefepime; the organism was resistant to both antibiotics."3.71Abiotrophia bacteremia in a patient with neutropenic fever and antimicrobial susceptibility testing of Abiotrophia isolates. ( Crawford, S; Jorgensen, JH; McElmeel, ML; Murray, CK; Walter, EA, 2001)
"Febrile neutropenia is an expected complication during treatment of aggressive hematological malignancies and hematopoietic cell transplantation."2.73The clinical impact of antibacterial prophylaxis and cycling antibiotics for febrile neutropenia in a hematological malignancy and transplantation unit. ( Craig, M; Cumpston, AD; Devetten, MP; Ericson, SG; Hobbs, GR; Sarwari, AR, 2007)
" Pharmacokinetic parameters of levofloxacin, including the maximum serum concentration (C(max)), time to C(max) (T(max)), area under the concentration-time curve (AUC), volume of distribution at steady state (V(ss)/F) and clearance (CL/F) were not statistically different at first dose and during neutropenia."2.71Pharmacokinetics and effects on bowel and throat microflora of oral levofloxacin as antibacterial prophylaxis in neutropenic patients with haematological malignancies. ( Dijstelbloem, Y; Huijgens, PC; Simoons-Smit, AM; Timmers, GJ; Touw, DJ; van Winkelhoff, AJ; Vandenbroucke-Grauls, CM, 2004)
"Both cancer centers differed in prophylactic antibiotic policies."2.69Bacteremia and fungemia in pediatric versus adult cancer patients after chemotherapy: comparison of etiology, risk factors and outcome. ( Foltinova, A; Kaiserova, E; Kiskova, M; Kovacicova, G; Krchnakova, A; Krcmery, V; Krupova, I; Kunova, A; Trupl, J; West, D, 1998)
" three times daily with dosage adjustment according to renal function and body weight (group 2)."2.67Empiric treatment of serious infections in patients with cancer: randomised comparison of two combinations. ( Maiche, AG; Teerenhovi, L, 1991)
"Patients who are treated for acute leukemia should be offered prophylaxis with ciprofloxacin or levofloxacin."2.43Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions. ( Bucaneve, G; Cullen, M; Fraser, A; Gafter-Gvili, A; Kern, WV; Leibovici, L; Paul, M, 2006)
"Levofloxacin is a fluoroquinolone antibiotic and is the optical S-(-) isomer of the racemic drug substance ofloxacin."2.40The clinical pharmacokinetics of levofloxacin. ( Chow, AT; Fish, DN, 1997)
"Gatifloxacin showed lower resistance levels than moxifloxacin."1.38[In vitro antibiotic susceptibility to fluoroquinolones]. ( Galvis, V; Rey, JJ; Tello, A; Villareal, D; Wong, CA, 2012)
"Paronychia is a well-known, but difficult to treat cutaneous toxicity associated with epidermal growth factor receptor (EGFR) inhibitor therapy."1.36Microbiological analysis of epidermal growth factor receptor inhibitor therapy-associated paronychia. ( Eames, T; Grabein, B; Kroth, J; Wollenberg, A, 2010)
" The aim of this study was to compare the therapeutic efficacy of quinupristin-dalfopristin (QD) alone, or in combination with gentamicin (G), teicoplanin (T), imipenem (I) or levofloxacin (L) against a strain of multidrug-resistant E."1.33[Comparative study of treatment with quinupristin-dalfopristin alone or in combination with gentamicin, teicoplanin, imipenem or levofloxacin in experimental endocarditis due to a multidrug-resistant Enterococcus faecium]. ( Gómez Gómez, J; López Fornás, F; Lorente Salinas, I; Martínez García, F; Pérez Salmerón, J; Roldán Conesa, D; Ruiz Gómez, J; Segovia Hernández, M; Valdés Chávarri, M, 2006)
"Ciprofloxacin was the most potent study drug against the family of Enterobacteriaceae and Pseudomonas spp."1.30Antibacterial activity of moxifloxacin (Bay 12-8039) against aerobic clinical isolates, and provisional criteria for disk susceptibility tests. ( Barry, AL; Brown, SD; Fuchs, PC, 1999)
"Sparfloxacin was more active than both ciprofloxacin and ofloxacin against all the isolates tested."1.29In vitro activity of sparfloxacin, ciprofloxacin, ofloxacin, and other antibiotics against bloodstream isolates of gram-positive cocci. ( Amsterdam, D; Beam, TR; Gorzynski, EA; Mandell, LA; Rotstein, C, 1993)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.85)18.7374
1990's15 (27.78)18.2507
2000's26 (48.15)29.6817
2010's11 (20.37)24.3611
2020's1 (1.85)2.80

Authors

AuthorsStudies
Ai, L1
Huang, H1
Wu, Z1
Liu, P1
Huang, J1
Chen, Y1
Romero-Trevejo, JL1
Somavilla-Lupiáñez, J1
Saidane, O1
Mahmoud, I1
Saadi, F1
Souayah, A1
Zouari, R1
Rasool, MH1
Siddique, AB1
Saqalein, M1
Asghar, MJ1
Zahoor, MA1
Aslam, B1
Shafiq, HB1
Nisar, MA1
Tsuchiya, Y1
Kobayakawa, S1
Tsuji, A1
Tochikubo, T1
Viale, P1
Furlanut, M1
Scudeller, L1
Pavan, F1
Negri, C1
Crapis, M1
Zamparini, E1
Zuiani, C1
Cristini, F1
Pea, F1
Reddy, AK1
Garg, P1
Alam, MR1
Gopinathan, U1
Sharma, S1
Krishnaiah, S1
Gupta, A1
Swaroop, C1
Agarwala, S1
Pandey, RM1
Bakhshi, S1
Eames, T1
Grabein, B1
Kroth, J1
Wollenberg, A1
Kim, HS1
Park, DW1
Youn, YK1
Jo, YM1
Kim, JY1
Song, JY1
Sohn, JW1
Cheong, HJ1
Kim, WJ1
Kim, MJ1
Choi, WS1
Cai, T1
Mazzoli, S1
Meacci, F1
Boddi, V1
Mondaini, N1
Malossini, G1
Bartoletti, R1
Yasufuku, T1
Shigemura, K1
Shirakawa, T1
Matsumoto, M1
Nakano, Y1
Tanaka, K1
Arakawa, S1
Kawabata, M1
Fujisawa, M1
Wong, CA1
Galvis, V1
Tello, A1
Villareal, D1
Rey, JJ1
Parra-Riffo, H1
Lemus-Peñaloza, J1
Tasaka, Y1
Suzuki, T2
Kawasaki, S1
Uda, T1
Mito, T1
Uno, T1
Ohashi, Y2
Matoba, AY1
Timmers, GJ1
Dijstelbloem, Y1
Simoons-Smit, AM1
van Winkelhoff, AJ1
Touw, DJ1
Vandenbroucke-Grauls, CM1
Huijgens, PC1
Taşkiran, B1
Colakoğlu, O1
Sözmen, B1
Unsal, B1
Aslan, SL1
Buyraç, Z1
Gopalachar, A1
Akins, RL1
Davis, WR1
Siddiqui, AA1
Ma, ES1
Wong, CL1
Lai, KT1
Chan, EC1
Yam, WC1
Chan, AC1
Pust, RA1
Ackenheil-Koppe, HR1
Gilbert, P1
Weidner, W1
Poole, M1
Anon, J1
Paglia, M1
Xiang, J1
Khashab, M1
Kahn, J1
Leibovici, L1
Paul, M1
Cullen, M1
Bucaneve, G1
Gafter-Gvili, A1
Fraser, A1
Kern, WV1
Pérez Salmerón, J1
Martínez García, F1
Roldán Conesa, D1
Lorente Salinas, I1
López Fornás, F1
Ruiz Gómez, J1
Gómez Gómez, J1
Segovia Hernández, M1
Valdés Chávarri, M1
Esposito, S2
Noviello, S2
Leone, S2
Marvaso, A1
Drago, L1
Marchetti, F1
Craig, M1
Cumpston, AD1
Hobbs, GR1
Devetten, MP1
Sarwari, AR1
Ericson, SG1
Ianniello, F1
Kailasanathan, A1
Anderson, DF1
Altiparmak, UE1
Ozer, PA1
Ozkuyumcu, C1
Us, AD1
Aslan, BS1
Duman, S1
Munir, WM1
El Mallah, MK1
Janda, WM1
Tu, EY1
Wada, T1
Kozai, S1
Tajika, T1
Sakaki, H1
Savitskaia, KI1
Tsar'kova, LN1
Shanina, AG1
Nasonov, VN1
Solodilova, OE1
Rusanova, EV1
Pfaller, MA1
Barry, AL2
Fuchs, PC2
Rotstein, C2
Amsterdam, D2
Beam, TR1
Mandell, LA2
Gorzynski, EA1
Fish, DN1
Chow, AT1
Tsuchimori, N1
Yamazaki, T1
Okonogi, K1
Krupova, I1
Kaiserova, E1
Foltinova, A1
Kovacicova, G1
Kiskova, M1
Krchnakova, A1
Kunova, A1
Trupl, J1
West, D1
Krcmery, V2
Colsky, AS1
Kirsner, RS1
Kerdel, FA1
Isenberg, HD1
Alperstein, P1
France, K1
Dhawan, VK1
Nachum, R1
Bhat, N1
Tolbert, L1
Agrawal, M1
Krupova, Y1
Novotny, J1
Sabo, A1
Mateicka, F1
von Eiff, C1
Peters, G1
Shah, PM1
Maesen, FP1
Dolmann, A1
Vetter, N1
Fiss, E1
Wesch, R1
Brown, SD1
Geddes, A1
Thaler, M1
Schonwald, S1
Härkönen, M1
Jacobs, F1
Nowotny, I1
Hardy, D1
Blondeau, JM1
Laskowski, R1
Bjarnason, J1
Stewart, C1
Alexandrakis, G1
Alfonso, EC1
Miller, D1
Manzella, J1
Benenson, R1
Pellerin, G1
Kellogg, J1
Bell, T1
Robertson, M1
Pope, D1
Murray, CK1
Walter, EA1
Crawford, S1
McElmeel, ML1
Jorgensen, JH1
Budanov, SV1
Smirnova, LB1
Ho, PL1
Ng, TK1
Yung, RW1
Que, TL1
Yip, EK1
Tse, CW1
Yuen, KY1
Kuriyama, T1
Karasawa, T1
Nakagawa, K1
Yamamoto, E1
Nakamura, S1
Maiche, AG1
Teerenhovi, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Contribution of Fast Molecular Bacterial Identification by Real-time PCR in Managing of Postoperative Acute Endophthalmitis[NCT02850653]150 participants (Anticipated)Interventional2007-11-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for ofloxacin and Gram-Positive Bacterial Infections

ArticleYear
Severe levofloxacin-induced hypoglycaemia: a case report and literature review.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2012, Jul-17, Volume: 32, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Catheter-Related Infections; Drug Therapy, Combination; Enterococcus; G

2012
Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions.
    Cancer, 2006, Oct-15, Volume: 107, Issue:8

    Topics: Acute Disease; Antibiotic Prophylaxis; Antineoplastic Agents; Bone Marrow Transplantation; Ciproflox

2006
The clinical pharmacokinetics of levofloxacin.
    Clinical pharmacokinetics, 1997, Volume: 32, Issue:2

    Topics: Anti-Infective Agents; Clinical Trials, Phase III as Topic; Drug Interactions; Gram-Negative Bacteri

1997
[Levofloxacin (Tavanic)--a novel quinolone of the III generation. Antimicrobial activity, pharmacokinetics, clinical significance].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2001, Volume: 46, Issue:5

    Topics: Anti-Infective Agents; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Levofloxa

2001

Trials

10 trials available for ofloxacin and Gram-Positive Bacterial Infections

ArticleYear
Randomized controlled trial comparing oral amoxicillin-clavulanate and ofloxacin with intravenous ceftriaxone and amikacin as outpatient therapy in pediatric low-risk febrile neutropenia.
    Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:9

    Topics: Administration, Oral; Adolescent; Ambulatory Care; Amikacin; Amoxicillin-Potassium Clavulanate Combi

2009
Pharmacokinetics and effects on bowel and throat microflora of oral levofloxacin as antibacterial prophylaxis in neutropenic patients with haematological malignancies.
    Bone marrow transplantation, 2004, Volume: 33, Issue:8

    Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Digestive System; Drug Resistance, Bacteri

2004
A trial of high-dose, short-course levofloxacin for the treatment of acute bacterial sinusitis.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2006, Volume: 134, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Double-Blind Me

2006
A pilot study on prevention of catheter-related urinary tract infections with fluoroquinolones.
    Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis;

2006
The clinical impact of antibacterial prophylaxis and cycling antibiotics for febrile neutropenia in a hematological malignancy and transplantation unit.
    Bone marrow transplantation, 2007, Volume: 39, Issue:8

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Drug Administration Schedule; Drug Resist

2007
[Use of ofloxacin in the treatment of infections of the lower respiratory tract].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1994, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Asthma; Bronchitis; Chronic Disease; Female; Gram-Negative Bacterial Infections;

1994
Bacteremia and fungemia in pediatric versus adult cancer patients after chemotherapy: comparison of etiology, risk factors and outcome.
    Journal of chemotherapy (Florence, Italy), 1998, Volume: 10, Issue:3

    Topics: Adult; Analysis of Variance; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; A

1998
Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbation of chronic bronchitis: results of a randomized, double-blind study.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Cefuroxime; Cephalosporins; Chron

1999
Levofloxacin in the empirical treatment of patients with suspected bacteraemia/sepsis: comparison with imipenem/cilastatin in an open, randomized trial.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteremia; Cilastatin; Cilastati

1999
Empiric treatment of serious infections in patients with cancer: randomised comparison of two combinations.
    Infection, 1991, Volume: 19 Suppl 6

    Topics: Administration, Oral; Cefotaxime; Drug Synergism; Drug Therapy, Combination; Gram-Negative Bacterial

1991

Other Studies

40 other studies available for ofloxacin and Gram-Positive Bacterial Infections

ArticleYear
Chronic suppurative otitis media due to Streptomyces cacaoi, the second case report in human infection.
    BMC infectious diseases, 2020, Jul-11, Volume: 20, Issue:1

    Topics: Anti-Bacterial Agents; China; Female; Gram-Positive Bacterial Infections; Humans; Middle Aged; Oflox

2020
Canaliculitis due to Gemella haemolysans in a single isolate.
    Archivos de la Sociedad Espanola de Oftalmologia, 2018, Volume: 93, Issue:6

    Topics: Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Canaliculitis; Combined Modality T

2018
[Spondylodiscitis and Lactococcus cremoris endocarditis].
    Medecine et maladies infectieuses, 2013, Volume: 43, Issue:11-12

    Topics: Aged; Animals; Anti-Bacterial Agents; Bacteremia; Braces; Cattle; Combined Modality Therapy; Disciti

2013
Occurrence and antibacterial susceptibility pattern of bacterial pathogens isolated from diarrheal patients in Pakistan.
    Saudi medical journal, 2016, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Bacillus cereus; Cef

2016
Preventive effect against post-cataract endophthalmitis: drug delivery intraocular lens versus intracameral antibiotics.
    Current eye research, 2008, Volume: 33, Issue:10

    Topics: Animals; Anterior Chamber; Anti-Bacterial Agents; Aqueous Humor; Biological Availability; Cataract E

2008
Treatment of pyogenic (non-tuberculous) spondylodiscitis with tailored high-dose levofloxacin plus rifampicin.
    International journal of antimicrobial agents, 2009, Volume: 33, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Discitis; Drug Monitoring; Female; Follow-Up

2009
Comparison of in vitro susceptibilities of Gram-positive cocci isolated from ocular infections against the second and fourth generation quinolones at a tertiary eye care centre in South India.
    Eye (London, England), 2010, Volume: 24, Issue:1

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Eye Infections, Bacterial; Female; Fluoroquinol

2010
Microbiological analysis of epidermal growth factor receptor inhibitor therapy-associated paronychia.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2010, Volume: 24, Issue:8

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Age

2010
Liver abscess and empyema due to Lactococcus lactis cremoris.
    Journal of Korean medical science, 2010, Volume: 25, Issue:11

    Topics: Adult; Anti-Bacterial Agents; Cefotaxime; Drainage; Empyema; Gram-Positive Bacterial Infections; Hum

2010
Epidemiological features and resistance pattern in uropathogens isolated from chronic bacterial prostatitis.
    Journal of microbiology (Seoul, Korea), 2011, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Enterococcus fa

2011
Mechanisms of and risk factors for fluoroquinolone resistance in clinical Enterococcus faecalis isolates from patients with urinary tract infections.
    Journal of clinical microbiology, 2011, Volume: 49, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; DNA Topoisomerase IV; Drug Resist

2011
[In vitro antibiotic susceptibility to fluoroquinolones].
    Archivos de la Sociedad Espanola de Oftalmologia, 2012, Volume: 87, Issue:3

    Topics: Acanthamoeba Keratitis; Anti-Bacterial Agents; Aza Compounds; Body Fluids; Ciprofloxacin; Colombia;

2012
Moxifloxacin as postoperative prophylaxis for Enterococcus faecalis-induced endophthalmitis after cataract surgery in aphakic rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2013, Volume: 29, Issue:4

    Topics: Administration, Ophthalmic; Animals; Anti-Bacterial Agents; Aphakia, Postcataract; Aza Compounds; Di

2013
Polymicrobial keratitis secondary to Burkholderia ambifaria, enterococcus, and staphylococcus aureus in a patient with herpetic stromal keratitis.
    American journal of ophthalmology, 2003, Volume: 136, Issue:4

    Topics: Amikacin; Burkholderia; Burkholderia Infections; Corneal Stroma; Drug Therapy, Combination; Enteroco

2003
Comparison of cefotaxime and ofloxacin in treatment of spontaneous bacterial peritonitis.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2004, Volume: 15, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Cefotaxime; Dose-Response Relationship, Drug; Drug Administration

2004
Urinary tract infection caused by Aerococcus viridans, a case report.
    Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:11

    Topics: Aged; Aged, 80 and over; Bacteremia; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male;

2004
Kocuria kristinae infection associated with acute cholecystitis.
    BMC infectious diseases, 2005, Jul-19, Volume: 5

    Topics: Acute Disease; Anti-Bacterial Agents; Cholecystitis; Gram-Positive Bacterial Infections; Humans; Lev

2005
Clinical efficacy of ofloxacin (tarivid) in patients with chronic bacterial prostatitis: preliminary results.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Adult; Anti-Infective Agents; Bacterial Infections; Clinical Trials as Topic; Escherichia coli Infec

1989
[Comparative study of treatment with quinupristin-dalfopristin alone or in combination with gentamicin, teicoplanin, imipenem or levofloxacin in experimental endocarditis due to a multidrug-resistant Enterococcus faecium].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2006, Volume: 19, Issue:3

    Topics: Aged; Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Resistance, Multiple, Bacterial;

2006
[In vitro activity of prulifloxacin, levofloxacin and ciprofloxacin against urinary pathogens].
    Le infezioni in medicina, 2006, Volume: 14, Issue:1

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Dioxolanes; Drug Resistance, Multiple, Bacterial; Fluoroquinol

2006
Infectious crystalline keratopathy caused by Gemella haemolysans.
    Cornea, 2007, Volume: 26, Issue:5

    Topics: Anti-Bacterial Agents; Cefuroxime; Colony Count, Microbial; Corneal Diseases; Drug Therapy, Combinat

2007
Postoperative endophthalmitis caused by Bacillus cereus and Chlamydia trachomatis.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:7

    Topics: Administration, Oral; Administration, Topical; Aged; Anti-Bacterial Agents; Bacillus cereus; Bacteri

2007
Gemella haemolysans infectious crystalline keratopathy.
    Cornea, 2008, Volume: 27, Issue:2

    Topics: Anti-Bacterial Agents; Cefuroxime; Colony Count, Microbial; Corneal Diseases; Drug Therapy, Combinat

2008
Prophylactic efficacy of ophthalmic quinolones in experimental endophthalmitis in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2008, Volume: 24, Issue:3

    Topics: Animals; Anterior Chamber; Anti-Bacterial Agents; Biological Availability; Disease Progression; Endo

2008
Levofloxacin disk potency and tentative interpretive criteria for susceptibility tests.
    Journal of clinical microbiology, 1993, Volume: 31, Issue:7

    Topics: Evaluation Studies as Topic; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positi

1993
In vitro activity of sparfloxacin, ciprofloxacin, ofloxacin, and other antibiotics against bloodstream isolates of gram-positive cocci.
    Diagnostic microbiology and infectious disease, 1993, Volume: 17, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquino

1993
Therapeutic effects of cefozopran against experimental mixed urinary tract infection with Enterococcus faecalis and Pseudomonas aeruginosa in mice.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:3

    Topics: Ampicillin; Animals; Cefozopran; Ceftazidime; Cephalosporins; Cilastatin; Enterococcus faecalis; Fem

1997
Analysis of antibiotic susceptibilities of skin wound flora in hospitalized dermatology patients. The crisis of antibiotic resistance has come to the surface.
    Archives of dermatology, 1998, Volume: 134, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Dermatitis; Drug Resistance, Microbial;

1998
In vitro susceptibility of recent gram-positive isolates to ciprofloxacin, levofloxacin, and trovafloxacin.
    Diagnostic microbiology and infectious disease, 1998, Volume: 32, Issue:2

    Topics: Anti-Infective Agents; Ciprofloxacin; Corynebacterium; Drug Resistance, Microbial; Fluoroquinolones;

1998
Vancomycin-resistant enterococcal colonization in nonhospitalized HIV-infected patients.
    The Western journal of medicine, 1998, Volume: 169, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Amoxicillin; Anti-Bacterial Agents; Bisexuality; Black

1998
Aetiology, cost of antimicrobial therapy and outcome in neutropenic patients who developed bacteraemia during antimicrobial prophylaxis: a case-control study.
    International journal of antimicrobial agents, 1998, Volume: 10, Issue:4

    Topics: Amikacin; Amphotericin B; Antibiotic Prophylaxis; Bacteremia; Bacterial Infections; Case-Control Stu

1998
In vitro activity of ciprofloxacin, ofloxacin, and levofloxacin against Micrococcus species and Stomatococcus mucilaginosus isolated from healthy subjects and neutropenic patients.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1998, Volume: 17, Issue:12

    Topics: Anti-Infective Agents; Ciprofloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Human

1998
Antibacterial activity of moxifloxacin (Bay 12-8039) against aerobic clinical isolates, and provisional criteria for disk susceptibility tests.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1999, Volume: 18, Issue:4

    Topics: Anti-Infective Agents; Aza Compounds; Bacteria, Aerobic; Ciprofloxacin; Fluoroquinolones; Gram-Negat

1999
Comparative in vitro activities of ciprofloxacin, gemifloxacin, grepafloxacin, moxifloxacin, ofloxacin, sparfloxacin, trovafloxacin, and other antimicrobial agents against bloodstream isolates of gram-positive cocci.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Fluoroquinol

2000
Comparative in vitro activity of gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin and trovafloxacin against 4151 Gram-negative and Gram-positive organisms.
    International journal of antimicrobial agents, 2000, Volume: 14, Issue:1

    Topics: Anti-Infective Agents; Aza Compounds; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gr

2000
Shifting trends in bacterial keratitis in south Florida and emerging resistance to fluoroquinolones.
    Ophthalmology, 2000, Volume: 107, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Cornea; Corneal Ulcer; Drug R

2000
Choice of antibiotic and risk of colonization with vancomycin-resistant Enterococcus among patients admitted for treatment of community-acquired pneumonia.
    Infection control and hospital epidemiology, 2000, Volume: 21, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxon

2000
Abiotrophia bacteremia in a patient with neutropenic fever and antimicrobial susceptibility testing of Abiotrophia isolates.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, May-15, Volume: 32, Issue:10

    Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Drug Resistance, Microbial; Fever; Gram

2001
Activity of linezolid against levofloxacin-resistant Streptococcus pneumoniae, methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci in Hong Kong.
    The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:4

    Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Gram-Positive Bacterial

2001
Bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections.
    Oral microbiology and immunology, 2002, Volume: 17, Issue:2

    Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactamases; Cefazolin; Cefotaxime; Ce

2002