Page last updated: 2024-11-01

ofloxacin and Glaucoma

ofloxacin has been researched along with Glaucoma in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"To report a case of herpes simplex virus reactivation after starting bimatoprost treatment for glaucoma."7.71Reactivation of herpes simplex virus keratitis after initiating bimatoprost treatment for glaucoma. ( Kroll, DM; Schuman, JS, 2002)
"To report a case of herpes simplex virus reactivation after starting bimatoprost treatment for glaucoma."3.71Reactivation of herpes simplex virus keratitis after initiating bimatoprost treatment for glaucoma. ( Kroll, DM; Schuman, JS, 2002)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MiƱo de Kaspar, H1
Kreutzer, TC1
Aguirre-Romo, I1
Ta, CN1
Dudichum, J1
Bayrhof, M1
Klauss, V1
Kampik, A1
Kroll, DM1
Schuman, JS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 4 Study on Effectiveness of Topical 0.5% Levofloxacin on Reduction of Preoperative Conjunctival Flora in Patients Scheduled for Intraocular Surgery[NCT00491049]Phase 4140 participants (Actual)Interventional2004-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ofloxacin and Glaucoma

ArticleYear
A prospective randomized study to determine the efficacy of preoperative topical levofloxacin in reducing conjunctival bacterial flora.
    American journal of ophthalmology, 2008, Volume: 145, Issue:1

    Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteria; Bacteriologi

2008

Other Studies

1 other study available for ofloxacin and Glaucoma

ArticleYear
Reactivation of herpes simplex virus keratitis after initiating bimatoprost treatment for glaucoma.
    American journal of ophthalmology, 2002, Volume: 133, Issue:3

    Topics: Acyclovir; Aged; Amides; Anti-Infective Agents; Anti-Inflammatory Agents; Antihypertensive Agents; A

2002