ofloxacin has been researched along with Gastroenteritis in 9 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Gastroenteritis: INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirteen hospitalized patients with various infections, five with typhoid fever, two with gastroenteritis, four with respiratory tract infection and two with biliary tract infection, were treated with ofloxacin at a daily dosage ranging between 600 and 900 mg orally." | 5.06 | Clinical experience with ofloxacin (DL 8280) in the therapy of various infections: preliminary report. ( Altucci, P; Briante, V; Cristiano, P; Leonessa, V; Morelli, G; Paradisi, F, 1986) |
| "Thirty-four hospitalized patients with various infections: 19 with typhoid fever, 4 with gastroenteritis, 7 with lower respiratory tract infections, 2 with biliary tract infections, 1 with brucellosis and 1 with infection of necrotic ulceration of the feet, were treated with ofloxacin at a daily dosage ranging between 600 and 900 mg orally." | 3.67 | Clinical experience with ofloxacin (DL-8280) in the therapy of various infections. ( Altucci, P; Cristiano, P; Iovene, MR; Mandia, L; Morelli, G; Paradisi, F, 1989) |
| "Acute diarrhea is a common disease worldwide and in Israel, a Mediterranean country." | 2.72 | Single-dose quinolone treatment in acute gastroenteritis. ( Ben-Valid, E; Hay, E; Kogan, E; Polishchuk, I; Reitblat, T; Weiler, Z; Zamir, D, 2006) |
| "Although cholera is an endemic disease in Bangladesh, India and other countries, it was never a significant cause of gastroenteritis in Pakistan before 1988." | 1.30 | Cholera in children in Karachi from 1990 through 1995: a study of cases admitted to a tertiary care hospital. ( Farooqui, BJ; Nizami, SQ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Regalado, NG | 1 |
| Martin, G | 1 |
| Antony, SJ | 1 |
| Zamir, D | 1 |
| Weiler, Z | 1 |
| Kogan, E | 1 |
| Ben-Valid, E | 1 |
| Hay, E | 1 |
| Reitblat, T | 1 |
| Polishchuk, I | 1 |
| Halstensen, A | 1 |
| Voltersvik, P | 1 |
| Gossius, G | 1 |
| Digranes, A | 1 |
| Peterson, LE | 1 |
| Rolstad, T | 1 |
| Solberg, CO | 1 |
| Noguerado, A | 1 |
| Garcia-Polo, I | 1 |
| Isasia, T | 1 |
| Jimenez, ML | 1 |
| Bermudez, P | 1 |
| Pita, J | 1 |
| Gabriel, R | 1 |
| Nizami, SQ | 1 |
| Farooqui, BJ | 1 |
| Yang, J | 1 |
| Baltatzis, S | 1 |
| Foster, CS | 1 |
| Lang, R | 1 |
| Lishner, M | 1 |
| Segev, S | 1 |
| Rubinstein, E | 1 |
| Cristiano, P | 2 |
| Iovene, MR | 1 |
| Morelli, G | 2 |
| Mandia, L | 1 |
| Paradisi, F | 2 |
| Altucci, P | 2 |
| Leonessa, V | 1 |
| Briante, V | 1 |
1 review available for ofloxacin and Gastroenteritis
| Article | Year |
|---|---|
Ofloxacin and the gastrointestinal tract: a potential role in the treatment of bacterial enteritis.
Topics: Administration, Oral; Digestive System; Drug Administration Schedule; Dysentery, Bacillary; Feces; G | 1990 |
4 trials available for ofloxacin and Gastroenteritis
| Article | Year |
|---|---|
Single-dose quinolone treatment in acute gastroenteritis.
Topics: Acute Disease; Adult; Analysis of Variance; Anti-Bacterial Agents; Diarrhea; Female; Gastroenteritis | 2006 |
Double-blind comparison of ofloxacin for 3 days and placebo in acute bacterial enteritis.
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Double-Blind Method; Gastroenteritis; | 1995 |
Early single dose therapy with ofloxacin for empirical treatment of acute gastroenteritis: a randomised, placebo-controlled double-blind clinical trial.
Topics: Acute Disease; Adult; Anti-Infective Agents; Diarrhea; Double-Blind Method; Feces; Female; Follow-Up | 1995 |
Clinical experience with ofloxacin (DL 8280) in the therapy of various infections: preliminary report.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cholangitis; Clinical Trials a | 1986 |
4 other studies available for ofloxacin and Gastroenteritis
| Article | Year |
|---|---|
Acinetobacter lwoffii: bacteremia associated with acute gastroenteritis.
Topics: Acinetobacter; Acinetobacter Infections; Acute Disease; Anti-Bacterial Agents; Bacteremia; Community | 2009 |
Cholera in children in Karachi from 1990 through 1995: a study of cases admitted to a tertiary care hospital.
Topics: Ampicillin Resistance; Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Child; Child, P | 1998 |
Peripheral ulcerative keratitis after Salmonella gastroenteritis.
Topics: Aged; Cornea; Corneal Neovascularization; Corneal Ulcer; Cyclopentolate; Drug Therapy, Combination; | 1998 |
Clinical experience with ofloxacin (DL-8280) in the therapy of various infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Child; Female; Gastroenteritis; Humans; Male; Middle | 1989 |