ofloxacin has been researched along with Gastritis in 11 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Gastritis: Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two groups exhibited similar adverse event rates (AEA 14." | 3.11 | Efficacy and Safety of Antofloxacin-Based Triple Therapy for Helicobacter pylori Eradication Failure in China. ( He, XJ; Jiang, CS; Li, DZ; Liu, G; Wang, W; Zeng, XP, 2022) |
| " dosing of levofloxacin (81%[95% CI: 78%-89%]vs 84%[95% CI: 66%-97%])." | 2.43 | Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis. ( Chey, WD; Kim, HM; Saad, RJ; Schoenfeld, P, 2006) |
| "Acute phlegmonous gastritis is an uncommon disease, often fatal condition characterized by suppurative bacterial infection of the gastric wall." | 1.37 | [A case of acute phlegmonous gastritis causing gastroparesis and cured with medical treatment alone]. ( Kim, JS; Kim, NY; Lee, KJ; Park, JS; Yun, HK, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| He, XJ | 1 |
| Zeng, XP | 1 |
| Jiang, CS | 1 |
| Liu, G | 1 |
| Li, DZ | 1 |
| Wang, W | 1 |
| Ishigami, T | 1 |
| Fujikawa, H | 1 |
| Miyagawa, M | 1 |
| Arakawa, Y | 1 |
| Abe, H | 1 |
| Ryuzaki, H | 1 |
| Matsuoka, S | 1 |
| Moriyama, M | 1 |
| Li, Y | 1 |
| Huang, X | 1 |
| Yao, L | 1 |
| Shi, R | 1 |
| Zhang, G | 1 |
| Zhang, J | 1 |
| Ye, LP | 1 |
| Li, W | 1 |
| Shen, LY | 1 |
| Kim, NY | 1 |
| Park, JS | 1 |
| Lee, KJ | 1 |
| Yun, HK | 1 |
| Kim, JS | 1 |
| Saad, RJ | 1 |
| Schoenfeld, P | 1 |
| Kim, HM | 1 |
| Chey, WD | 1 |
| Vakil, N | 1 |
| Nista, EC | 1 |
| Candelli, M | 1 |
| Zocco, MA | 1 |
| Cremonini, F | 1 |
| Ojetti, V | 1 |
| Finizio, R | 1 |
| Spada, C | 1 |
| Cammarota, G | 1 |
| Gasbarrini, G | 1 |
| Gasbarrini, A | 1 |
| Zullo, A | 1 |
| Hassan, C | 1 |
| Lorenzetti, R | 1 |
| Morini, S | 1 |
| Zelenková, J | 1 |
| Toman, R | 1 |
| Bielaszewská, M | 1 |
| Hanika, J | 1 |
| Zeman, V | 1 |
| Glupczynski, Y | 1 |
| Labbe, M | 1 |
| Burette, A | 1 |
| Delmee, M | 1 |
| Avesani, V | 1 |
| Bruck, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Randomized Trial of Levofloxacin-amoxicillin Triple Therapy vs. Levofloxacin-tetracycline Quadruple Therapy in Second-line Helicobacter Pylori Treatment[NCT02978157] | 102 participants (Actual) | Interventional | 2015-02-28 | Completed | |||
| Comparison of Two Rescue Therapies for Helicobacter Pylori Infection - A Multicenter Randomized Controlled Trial[NCT02547012] | 51 participants (Actual) | Interventional | 2013-11-30 | Completed | |||
| Personalized Treatment for Refractory H Pylori Infection[NCT02547025] | 126 participants (Actual) | Interventional | 2012-08-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of participants with negative H pylori status in follow-up tests as a measure of successful eradication (NCT02978157)
Timeframe: six weeks after the end of anti-H pylori therapy.
| Intervention | participants (Number) |
|---|---|
| Esomeprazole+Amox+Levo | 36 |
| Esomeprazole+Bismuth+Tetra+Levo | 49 |
Evaluate eradication outcome by endoscopy urease test and histology or urea breath test (NCT02547012)
Timeframe: six weeks after the end of anti-H pylori therapy.
| Intervention | participants (Number) |
|---|---|
| Esomeprazole+Amox+Levo+Tetra | 13 |
| Esomeprazole+Amox+Levo | 21 |
2 reviews available for ofloxacin and Gastritis
| Article | Year |
|---|---|
Advantages of Moxifloxacin and Levofloxacin-based triple therapy for second-line treatments of persistent Helicobacter pylori infection: a meta analysis.
Topics: Anti-Infective Agents; Aza Compounds; Bismuth; Clarithromycin; Drug Administration Schedule; Drug Re | 2010 |
Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Gast | 2006 |
Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Gast | 2006 |
Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Gast | 2006 |
Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Gast | 2006 |
Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Gast | 2006 |
Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Gast | 2006 |
Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Gast | 2006 |
Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Gast | 2006 |
Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Gast | 2006 |
3 trials available for ofloxacin and Gastritis
| Article | Year |
|---|---|
Efficacy and Safety of Antofloxacin-Based Triple Therapy for Helicobacter pylori Eradication Failure in China.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; China; Drug Therapy, Combination; Esomepraz | 2022 |
Levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori eradication.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Biopsy; Clarithromycin; Drug Therapy, Combination; E | 2006 |
Treatment failure of ofloxacin in Campylobacter pylori infection.
Topics: Anti-Bacterial Agents; Campylobacter; Campylobacter Infections; Clinical Trials as Topic; Double-Bli | 1987 |
6 other studies available for ofloxacin and Gastritis
| Article | Year |
|---|---|
[A case of phlegmonous gastritis which resolved with medical treatment].
Topics: Aged; Anti-Bacterial Agents; Cellulitis; Drug Therapy, Combination; Female; Gastritis; Humans; Levof | 2008 |
Iatrogenic gastric wall abscess infected with Enterobacter cloacae after biopsy.
Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Diagnosis, Differential; Drug Therapy, Comb | 2010 |
[A case of acute phlegmonous gastritis causing gastroparesis and cured with medical treatment alone].
Topics: Acinetobacter; Acute Disease; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime; Ceftri | 2011 |
Helicobacter pylori treatment: a practical approach.
Topics: Bismuth; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; | 2006 |
Helicobacter pylori eradication: do we have another ace up our sleeve?
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Adult; Anti-Infective Agents; Be | 2001 |
[Campylobacter pylori and treatment of duodenal ulcer].
Topics: Adult; Campylobacter; Campylobacter Infections; Duodenal Ulcer; Female; Gastritis; Humans; Male; Mid | 1990 |