Page last updated: 2024-11-01

ofloxacin and Fungal Diseases

ofloxacin has been researched along with Fungal Diseases in 7 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"Corneal cross-linking (CXL) with riboflavin is being used more frequently for the treatment of therapy-resistant microbial keratitis, since increasing drug resistance and specific pathogens, e."3.80[Corneal cross-linking in microbial keratitis to prevent à chaud keratoplasty: a retrospective case series]. ( Ammermann, C; Cursiefen, C; Hermann, M, 2014)
"Thus, up to date management of cancer patients, in addition to other supportive care modalities, should also incorporate diagnostic methods and therapy of infections."2.47[Treatment and prevention of infections in cancer patients with neutropenia]. ( Sinkó, J, 2011)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shrestha, SK1
Kril, LM1
Green, KD1
Kwiatkowski, S1
Sviripa, VM1
Nickell, JR1
Dwoskin, LP1
Watt, DS1
Garneau-Tsodikova, S1
Ammermann, C1
Cursiefen, C1
Hermann, M1
Hekiert, AM1
Cohen, MB1
Montone, KT1
Palmer, JN1
Govindaraj, S1
Sinkó, J1
Zeuli, JD1
Wilson, JW1
Estes, LL1
Kocatürk, T1
Pineda, R1
Green, LK1
Azar, DT1
Bertini, M1
Freilone, R1
Vitolo, U1
Botto, B1
Ciotti, R1
Cinieri, S1
Di Nota, A1
Di Vito, F1
Levis, A1
Orsucci, L1
Pini, M1
Rota-Scalabrini, D1
Todeschini, G1
Resegotti, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Trial of Tamoxifen Combined With Amphotericin B and Fluconazole for Cryptococcal Meningitis[NCT03112031]Phase 250 participants (Actual)Interventional2017-10-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ofloxacin and Fungal Diseases

ArticleYear
[Treatment and prevention of infections in cancer patients with neutropenia].
    Magyar onkologia, 2011, Volume: 55, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antineoplastic Agents; Bacterial In

2011

Trials

1 trial available for ofloxacin and Fungal Diseases

ArticleYear
The treatment of elderly patients with aggressive non-Hodgkin's lymphomas: feasibility and efficacy of an intensive multidrug regimen.
    Leukemia & lymphoma, 1996, Volume: 22, Issue:5-6

    Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Antifungal Agents; Antineoplastic Combined Chem

1996

Other Studies

5 other studies available for ofloxacin and Fungal Diseases

ArticleYear
Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents.
    Bioorganic & medicinal chemistry, 2017, 01-01, Volume: 25, Issue:1

    Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Bacterial Infections; Candida albicans; Candidia

2017
[Corneal cross-linking in microbial keratitis to prevent à chaud keratoplasty: a retrospective case series].
    Klinische Monatsblatter fur Augenheilkunde, 2014, Volume: 231, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Biological Dressings; C

2014
Ecthyma gangrenosum mimicking acute invasive fungal sinusitis in an immunocompromised patient.
    Ear, nose, & throat journal, 2010, Volume: 89, Issue:6

    Topics: Acetamides; Adult; Anti-Bacterial Agents; Diagnosis, Differential; Ecthyma; Humans; Immunocompromise

2010
Effect of combined fluoroquinolone and azole use on QT prolongation in hematology patients.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3

    Topics: Adult; Aged; Antifungal Agents; Drug Administration Schedule; Drug Therapy, Combination; Electrocard

2013
Post-LASIK epithelial dendritic defect associated with Alternaria.
    Cornea, 2007, Volume: 26, Issue:9

    Topics: Alternaria; Amphotericin B; Antifungal Agents; Combined Modality Therapy; Corneal Ulcer; Debridement

2007