Page last updated: 2024-11-01

ofloxacin and Foreign Bodies

ofloxacin has been researched along with Foreign Bodies in 6 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Foreign Bodies: Inanimate objects that become enclosed in the body.

Research Excerpts

ExcerptRelevanceReference
" The efficacy of the rifampin-levofloxacin combination is not significantly improved by the dosage of levofloxacin."1.35Antagonistic effect of rifampin on the efficacy of high-dose levofloxacin in staphylococcal experimental foreign-body infection. ( Ariza, J; Cabellos, C; Cabo, J; Euba, G; Gudiol, F; Murillo, O; Pachón, ME; Tubau, F; Verdaguer, R, 2008)
"Levofloxacin was more efficient than cloxacillin (P < 0."1.35Intracellular antimicrobial activity appearing as a relevant factor in antibiotic efficacy against an experimental foreign-body infection caused by Staphylococcus aureus. ( Ariza, J; Cabellos, C; Cabo, J; Carreras, M; Euba, G; Gudiol, F; Murillo, O; Pachón, ME; Verdaguer, R, 2009)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Murillo, O3
Pachón, ME3
Euba, G3
Verdaguer, R3
Tubau, F2
Cabellos, C3
Cabo, J3
Gudiol, F3
Ariza, J3
Filsoof, DM1
Park, SY1
Carreras, M1
Hart, E1
Azzopardi, K1
Taing, H1
Graichen, F1
Jeffery, J1
Mayadunne, R1
Wickramaratna, M1
O'Shea, M1
Nijagal, B1
Watkinson, R1
O'Leary, S1
Finnin, B1
Tait, R1
Robins-Browne, R1
Tenke, P1
Kovacs, B1
Benkõ, R1
Ashaber, D1
Nagy, E1

Other Studies

6 other studies available for ofloxacin and Foreign Bodies

ArticleYear
Antagonistic effect of rifampin on the efficacy of high-dose levofloxacin in staphylococcal experimental foreign-body infection.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Drug Interactions; Forei

2008
High doses of levofloxacin vs moxifloxacin against staphylococcal experimental foreign-body infection: the effect of higher MIC-related pharmacokinetic parameters on efficacy.
    The Journal of infection, 2009, Volume: 58, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Fluoroquinolones; Foreign Bodies; Levofloxacin; Male;

2009
Eustachian tube foreign body undetected for 30 years: case report.
    Ear, nose, & throat journal, 2009, Volume: 88, Issue:4

    Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Eustachian Tube; Foreign Bodies; Hearing Loss, Conduct

2009
Intracellular antimicrobial activity appearing as a relevant factor in antibiotic efficacy against an experimental foreign-body infection caused by Staphylococcus aureus.
    The Journal of antimicrobial chemotherapy, 2009, Volume: 64, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Cloxacillin; Colony Count, Microbial; Cytoplasm; Disease Models, Ani

2009
Efficacy of antimicrobial polymer coatings in an animal model of bacterial infection associated with foreign body implants.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Disease Models, Animal; Female; Foreign Bod

2010
Continuous versus intermittent levofloxacin treatment in complicated urinary tract infections caused by urinary obstruction temporarily relieved by foreign body insertion.
    International journal of antimicrobial agents, 2006, Volume: 28 Suppl 1

    Topics: Anti-Infective Agents, Urinary; Biofilms; Drug Administration Schedule; Female; Foreign Bodies; Huma

2006