ofloxacin has been researched along with Eye Infections in 8 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Eye Infections: Infection, moderate to severe, caused by bacteria, fungi, or viruses, which occurs either on the external surface of the eye or intraocularly with probable inflammation, visual impairment, or blindness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Information from 6760 patients receiving levofloxacin for the treatment of a variety of ocular infections was collected." | 7.78 | Post-marketing surveillance of levofloxacin 0.5% ophthalmic solution for external ocular infections. ( Fukumoto, M; Hashimoto, M; Ishida, C; Kanda, Y; Kayama, T; Kunihiro, E; Okamoto, S; Yanai, T, 2012) |
| "In this retrospective, longitudinal study, the microbiology laboratory records of patients with different ocular infections diagnosed at an eye institute in central India from 2005-2020 were reviewed to determine the pattern of fluoroquinolone (ciprofloxacin, ofloxacin, gatifloxacin, and moxifloxacin) resistance." | 4.12 | Fluoroquinolone resistance in bacterial isolates from ocular infections: Trend in antibiotic susceptibility patterns between 2005-2020. ( Agrawal, D; Chatterjee, S; Gangwe, AB; Gomase, SN; Mishra, M; Parchand, SM, 2022) |
| "Information from 6760 patients receiving levofloxacin for the treatment of a variety of ocular infections was collected." | 3.78 | Post-marketing surveillance of levofloxacin 0.5% ophthalmic solution for external ocular infections. ( Fukumoto, M; Hashimoto, M; Ishida, C; Kanda, Y; Kayama, T; Kunihiro, E; Okamoto, S; Yanai, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chatterjee, S | 3 |
| Agrawal, D | 3 |
| Gomase, SN | 3 |
| Parchand, SM | 3 |
| Gangwe, AB | 3 |
| Mishra, M | 3 |
| Keating, GM | 1 |
| Bai, XQ | 1 |
| Wang, ZQ | 1 |
| Li, R | 1 |
| Luo, SY | 1 |
| Deng, SJ | 1 |
| Liang, QF | 1 |
| Sun, XG | 1 |
| Kanda, Y | 1 |
| Kayama, T | 1 |
| Okamoto, S | 1 |
| Hashimoto, M | 1 |
| Ishida, C | 1 |
| Yanai, T | 1 |
| Fukumoto, M | 1 |
| Kunihiro, E | 1 |
| Akkan, AG | 1 |
| Mutlu, I | 1 |
| Ozyazgan, S | 1 |
| Gok, A | 1 |
| Yigit, U | 1 |
| Ozuner, Z | 1 |
| Senses, V | 1 |
| Pekel, H | 1 |
| Hehl, EM | 1 |
| Beck, R | 1 |
| Luthard, K | 1 |
| Guthoff, R | 1 |
| Drewelow, B | 1 |
| Cernák, A | 1 |
| Gerinec, A | 1 |
| Ghelardi, E | 1 |
| Tavanti, A | 1 |
| Celandroni, F | 1 |
| Lupetti, A | 1 |
| Blandizzi, C | 1 |
| Boldrini, E | 1 |
| Campa, M | 1 |
| Senesi, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intracameral Levofloxacin (0.5%) Versus Intracameral Cefuroxime (1mg/0.1ml) Effect on Corneal Endothelial Cell Count and Morphology in Uneventful Phacoemulsification[NCT04212078] | Phase 1/Phase 2 | 138 participants (Anticipated) | Interventional | 2019-07-29 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ofloxacin and Eye Infections
| Article | Year |
|---|---|
Levofloxacin 0.5% ophthalmic solution: a review of its use in the treatment of external ocular infections and in intraocular surgery.
Topics: Anti-Bacterial Agents; Conjunctivitis; Drug Resistance, Bacterial; Eye Infections; Humans; Levofloxa | 2009 |
2 trials available for ofloxacin and Eye Infections
| Article | Year |
|---|---|
Penetration of topically applied ciprofloxacin, norfloxacin and ofloxacin into the aqueous humor of the uninflamed human eye.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Aqu | 1997 |
Improved penetration of aminoglycosides and fluorozuinolones into the aqueous humour of patients by means of Acuvue contact lenses.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agent | 1999 |
5 other studies available for ofloxacin and Eye Infections
| Article | Year |
|---|---|
Fluoroquinolone resistance in bacterial isolates from ocular infections: Trend in antibiotic susceptibility patterns between 2005-2020.
Topics: Anti-Bacterial Agents; Cefuroxime; Ciprofloxacin; Colistin; Eye Infections; Fluoroquinolones; Gatifl | 2022 |
Fluoroquinolone resistance in bacterial isolates from ocular infections: Trend in antibiotic susceptibility patterns between 2005-2020.
Topics: Anti-Bacterial Agents; Cefuroxime; Ciprofloxacin; Colistin; Eye Infections; Fluoroquinolones; Gatifl | 2022 |
Fluoroquinolone resistance in bacterial isolates from ocular infections: Trend in antibiotic susceptibility patterns between 2005-2020.
Topics: Anti-Bacterial Agents; Cefuroxime; Ciprofloxacin; Colistin; Eye Infections; Fluoroquinolones; Gatifl | 2022 |
Fluoroquinolone resistance in bacterial isolates from ocular infections: Trend in antibiotic susceptibility patterns between 2005-2020.
Topics: Anti-Bacterial Agents; Cefuroxime; Ciprofloxacin; Colistin; Eye Infections; Fluoroquinolones; Gatifl | 2022 |
[Etiological analysis of ocular non-viral microbial isolates in children and their antibiotics susceptibility in vitro].
Topics: Adolescent; Anti-Infective Agents; Bacteria; Child; Child, Preschool; Drug Resistance, Microbial; Ey | 2009 |
Post-marketing surveillance of levofloxacin 0.5% ophthalmic solution for external ocular infections.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Drug-Related Side Effects a | 2012 |
[Clinical experience with the preparation Uniflox Unimed Pharma in ophthalmology].
Topics: Adolescent; Adult; Anti-Infective Agents; Child; Child, Preschool; Eye Infections; Humans; Infant; O | 2000 |
Effect of a novel mucoadhesive polysaccharide obtained from tamarind seeds on the intraocular penetration of gentamicin and ofloxacin in rabbits.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Aqueous Humor; Drug | 2000 |