ofloxacin has been researched along with Eye Disorders in 10 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gentamicin was found to penetrate the vitreous very poorly." | 1.29 | Penetration of gentamicin and ofloxacin in human vitreous after systemic administration. ( Van de Velde, E; Verbraeken, H; Verschraegen, G; Verstraete, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tian, Q | 1 |
| Qian, J | 1 |
| Zhao, Y | 1 |
| Guo, D | 1 |
| Song, J | 1 |
| Bi, H | 1 |
| Kim, MS | 1 |
| Kim, HK | 1 |
| Kim, JM | 1 |
| Choi, CY | 1 |
| Bains, HS | 1 |
| Jampol, LM | 1 |
| Caughron, MC | 1 |
| Parnell, JR | 1 |
| Listernick, R | 1 |
| Deguchi, K | 1 |
| Yokota, N | 1 |
| Koguchi, M | 1 |
| Suzuki, Y | 1 |
| Suzuki, K | 1 |
| Fukayama, S | 1 |
| Ishihara, R | 1 |
| Oda, S | 1 |
| Verbraeken, H | 1 |
| Verstraete, A | 1 |
| Van de Velde, E | 1 |
| Verschraegen, G | 1 |
| Fiscella, RG | 1 |
| Shapiro, MJ | 1 |
| Solomon, MJ | 1 |
| Kurtz, RM | 1 |
| Mui, S | 1 |
| Labib, S | 1 |
| Baum, J | 1 |
| Roberts, C | 1 |
| Nomura, M | 1 |
| Yamada, M | 1 |
| Yamamura, H | 1 |
| Kajimura, T | 1 |
| Takayama, S | 1 |
1 trial available for ofloxacin and Eye Disorders
| Article | Year |
|---|---|
Comparison of the ocular comfort of ofloxacin 0.3% ophthalmic solution and lubricant eye drops.
Topics: Adult; Anti-Infective Agents; Eye; Eye Diseases; Female; Humans; Lubrication; Male; Ofloxacin; Ophth | 2002 |
9 other studies available for ofloxacin and Eye Disorders
| Article | Year |
|---|---|
Rabbit-derived human Thelazia callipaeda infection: a case report.
Topics: Animals; Eye Diseases; Female; Humans; Ofloxacin; Rabbits; Spirurida Infections; Thelazioidea | 2022 |
Comparison of contamination rates between preserved and preservative-free fluoroquinolone eyedrops.
Topics: Anti-Bacterial Agents; Aspergillus niger; Bacteria; Bacteriological Techniques; Benzalkonium Compoun | 2013 |
Vitritis and chorioretinitis in a patient with West Nile virus infection.
Topics: Anti-Infective Agents; Antibodies, Viral; Chorioretinitis; Drug Therapy, Combination; Eye Diseases; | 2003 |
A 5-year-old girl with headache and eye pain.
Topics: Abducens Nerve Diseases; Anti-Bacterial Agents; Child, Preschool; Cranial Sinuses; Diagnosis, Differ | 2008 |
[Antibacterial activities of ofloxacin against recent clinical isolates from patients with ocular infections].
Topics: Drug Resistance, Microbial; Eye Diseases; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Of | 1993 |
Penetration of gentamicin and ofloxacin in human vitreous after systemic administration.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Chromatography, High Pressure Liqui | 1996 |
Ofloxacin penetration into the eye after intravenous and topical administration.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiot | 1997 |
Multicenter drug study assessing in vitro antibiotic susceptibilities of ocular isolates.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Drug Resistance, Microbial; Eye Diseases; Hu | 1998 |
Ophthalmotoxicity and ototoxicity of the new quinolone antibacterial agent levofloxacin in Long Evans rats.
Topics: Animals; Anti-Infective Agents; Electroretinography; Eye Diseases; Female; Hearing; Hearing Disorder | 1992 |