ofloxacin has been researched along with Experimental Radiation Injuries in 4 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of oral therapy with three quinolones (ofloxacin, ciprofloxacin, and pefloxacin) in the prevention of postirradiation bacteremia and mortality was tested in B6D2F1 mice given 9." | 3.68 | Quinolone therapy in the prevention of mortality after irradiation. ( Brook, I; Elliott, TB, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ledney, GD | 3 |
| Elliott, TB | 3 |
| Landauer, MR | 1 |
| Vigneulle, RM | 1 |
| Henderson, PL | 1 |
| Harding, RA | 1 |
| Tom, SP | 1 |
| Brook, I | 3 |
4 other studies available for ofloxacin and Experimental Radiation Injuries
| Article | Year |
|---|---|
Survival of irradiated mice treated with WR-151327, synthetic trehalose dicorynomycolate, or ofloxacin.
Topics: Adjuvants, Immunologic; Animals; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Cord Factors; F | 1994 |
Quinolone therapy in the prevention of mortality after irradiation.
Topics: Animals; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Cobalt Radioisotopes; Female; Gamma Rays; | 1991 |
Ofloxacin and penicillin G combination therapy in prevention of bacterial translocation and animal mortality after irradiation.
Topics: Animals; Drug Therapy, Combination; Enterobacteriaceae; Female; Liver; Mice; Mice, Inbred C3H; Oflox | 1991 |
Quinolone therapy of Klebsiella pneumoniae sepsis following irradiation: comparison of pefloxacin, ciprofloxacin, and ofloxacin.
Topics: Animals; Ciprofloxacin; Female; Klebsiella Infections; Klebsiella pneumoniae; Mice; Ofloxacin; Peflo | 1990 |