Page last updated: 2024-11-01

ofloxacin and Escherichia coli Meningitis

ofloxacin has been researched along with Escherichia coli Meningitis in 1 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"We have assessed levofloxacin penetration in cerebrospinal fluid (CSF) and the liquor-to-plasma ratio (C(L)/C(P)) at 2 hours after dosing in 5 patients with spontaneous acute bacterial meningitis."1.31Cerebrospinal fluid penetration of levofloxacin in patients with spontaneous acute bacterial meningitis. ( Baraldo, M; Furlanut, M; Giobbia, M; Pea, F; Scotton, PG; Vaglia, A, 2001)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scotton, PG1
Pea, F1
Giobbia, M1
Baraldo, M1
Vaglia, A1
Furlanut, M1

Other Studies

1 other study available for ofloxacin and Escherichia coli Meningitis

ArticleYear
Cerebrospinal fluid penetration of levofloxacin in patients with spontaneous acute bacterial meningitis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Nov-01, Volume: 33, Issue:9

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Meningitis, E

2001