ofloxacin has been researched along with Epididymitis in 18 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Epididymitis: Inflammation of the EPIDIDYMIS. Its clinical features include enlarged epididymis, a swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The in vivo efficacy of ofloxacin was compared with those of cefotaxime and doxycycline in a rat model of epididymitis due to Escherichia coli." | 7.68 | Comparative efficacies of ofloxacin, cefotaxime, and doxycycline for treatment of experimental epididymitis due to Escherichia coli in rats. ( Jantos, C; Schiefer, HG; Schmidts, HL; Vieler, E; Weidner, W, 1993) |
| "In a prospective study, 70 men suffering from uncomplicated acute unilateral epididymitis were treated initially with 2 x 200 mg ofloxacin p." | 7.68 | [Initial therapy of acute unilateral epididymitis using ofloxacin. I. Clinical and microbiological findings]. ( Friedrich, HJ; Garbe, C; Harbrecht, J; Kleinschmidt, K; Schiefer, HG; Weidner, W; Weissbach, L, 1990) |
| "Levofloxacin was given to each patient at a dose of 300 mg or 400 mg a day for 7-14 days (average 12." | 5.28 | [Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis]. ( Horiba, M; Suzuki, K, 1992) |
| "To report a fatal case of toxic epidermal necrolysis in a man who was treated with oral ofloxacin for epididymitis." | 3.71 | Ofloxacin: a probable cause of toxic epidermal necrolysis. ( Melde, SL, 2001) |
| "The in vivo efficacy of ofloxacin was compared with those of cefotaxime and doxycycline in a rat model of epididymitis due to Escherichia coli." | 3.68 | Comparative efficacies of ofloxacin, cefotaxime, and doxycycline for treatment of experimental epididymitis due to Escherichia coli in rats. ( Jantos, C; Schiefer, HG; Schmidts, HL; Vieler, E; Weidner, W, 1993) |
| "In a prospective study, 70 men suffering from uncomplicated acute unilateral epididymitis were treated initially with 2 x 200 mg ofloxacin p." | 3.68 | [Initial therapy of acute unilateral epididymitis using ofloxacin. I. Clinical and microbiological findings]. ( Friedrich, HJ; Garbe, C; Harbrecht, J; Kleinschmidt, K; Schiefer, HG; Weidner, W; Weissbach, L, 1990) |
| "In this study, 20 men suffering from acute nongonococcal epididymitis were treated with ofloxacin 200mg bid given orally for 2 weeks." | 3.67 | Acute nongonococcal epididymitis. Aetiological and therapeutic aspects. ( Garbe, C; Schiefer, HG; Weidner, W, 1987) |
| " In practice, adverse events (AEs) of BCG therapy could restrict its prescription by urologists." | 2.48 | [Diagnosis and management of adverse events occuring during BCG therapy for non-muscle invasive bladder cancer (NMIBC): review of the Cancer Committee of the French Association of Urology]. ( Davin, JL; Irani, J; Larré, S; Moreau, JL; Neuzillet, Y; Pfister, C; Pignot, G; Rouprêt, M; Soulié, M; Wallerand, H, 2012) |
| "In countries such as India, where Salmonella infections are endemic, a high index of suspicion should be always be maintained and the possibility of a Salmonella infection at an aberrant site where it is hardly expected should not be ruled out." | 1.38 | Epididymo-orchitis: an unusual manifestation of salmonellosis. ( Bansal, N; Chander, J; Kaistha, N, 2012) |
| "Acute epididymitis is increasing in men aged 35 years or under due to sexually-transmitted Chlamydia trachomatis." | 1.32 | Management of acute epididymitis: are European guidelines being followed? ( Adamson, AS; Breitenfeldt, N; Drury, NE; Dyer, JP; Harrison, GS, 2004) |
| "Levofloxacin was given to each patient at a dose of 300 mg or 400 mg a day for 7-14 days (average 12." | 1.28 | [Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis]. ( Horiba, M; Suzuki, K, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Mahony, C | 1 |
| Evans-Jones, J | 1 |
| Bansal, N | 1 |
| Kaistha, N | 1 |
| Chander, J | 1 |
| La Vignera, S | 1 |
| Condorelli, RA | 1 |
| Calogero, AE | 1 |
| Bellanca, S | 1 |
| Salmeri, M | 1 |
| Vicari, E | 2 |
| Neuzillet, Y | 1 |
| Rouprêt, M | 1 |
| Wallerand, H | 1 |
| Pignot, G | 1 |
| Larré, S | 1 |
| Irani, J | 1 |
| Davin, JL | 1 |
| Moreau, JL | 1 |
| Soulié, M | 1 |
| Pfister, C | 1 |
| Jeon, SS | 1 |
| Woo, SH | 1 |
| Hyun, JH | 1 |
| Choi, HY | 1 |
| Chai, SE | 1 |
| Donzella, JG | 1 |
| Merrick, GS | 1 |
| Lindert, DJ | 1 |
| Andreini, HJ | 1 |
| Curtis, RL | 1 |
| Luna, IH | 1 |
| Allen, Z | 1 |
| Butler, WM | 1 |
| Drury, NE | 1 |
| Dyer, JP | 1 |
| Breitenfeldt, N | 1 |
| Adamson, AS | 1 |
| Harrison, GS | 1 |
| Tatlişen, A | 1 |
| Carpinlioğlu, M | 1 |
| Sümerkan, B | 1 |
| Gülmez, I | 1 |
| Karacagil, M | 1 |
| Vieler, E | 1 |
| Jantos, C | 1 |
| Schmidts, HL | 1 |
| Weidner, W | 4 |
| Schiefer, HG | 4 |
| Melde, SL | 1 |
| Saito, I | 1 |
| Suzuki, A | 1 |
| Saiko, Y | 1 |
| Yokozawa, M | 1 |
| Ono, K | 1 |
| Miyata, K | 1 |
| Miyamura, R | 1 |
| Hamaya, O | 1 |
| Kaneko, K | 1 |
| Yamamoto, T | 1 |
| Suzuki, K | 1 |
| Horiba, M | 1 |
| Garbe, C | 3 |
| Weissbach, L | 2 |
| Harbrecht, J | 2 |
| Kleinschmidt, K | 2 |
| Friedrich, HJ | 2 |
| Melekos, MD | 1 |
| Asbach, HW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial to Investigate the Infectious Outcomes of Intrarectal Povidone-iodine Cleansing Plus Formalin Disinfection of Needle Tip During Transrectal Ultrasound Guided Prostate Biopsy[NCT03879486] | 1,257 participants (Actual) | Interventional | 2017-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ofloxacin and Epididymitis
| Article | Year |
|---|---|
[Diagnosis and management of adverse events occuring during BCG therapy for non-muscle invasive bladder cancer (NMIBC): review of the Cancer Committee of the French Association of Urology].
Topics: Adjuvants, Immunologic; Administration, Intravesical; Anti-Infective Agents, Urinary; Arthralgia; BC | 2012 |
1 trial available for ofloxacin and Epididymitis
| Article | Year |
|---|---|
Effectiveness and limits of antimicrobial treatment on seminal leukocyte concentration and related reactive oxygen species production in patients with male accessory gland infection.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Doxycycline; Epididymitis; Femal | 2000 |
16 other studies available for ofloxacin and Epididymitis
| Article | Year |
|---|---|
Urological management of epididymo-orchitis: simple, ofloxacin for all!
Topics: Anti-Bacterial Agents; Epididymitis; Humans; Male; Ofloxacin; Orchitis | 2011 |
Epididymo-orchitis: an unusual manifestation of salmonellosis.
Topics: Abscess; Administration, Intravenous; Administration, Oral; Ceftriaxone; Ciprofloxacin; Developing C | 2012 |
Persistence of ultrasound alterations after antibiotic treatment with levofloxacin in patients with male accessory gland infection.
Topics: Adult; Anti-Bacterial Agents; Epididymis; Epididymitis; Genital Diseases, Male; Humans; Levofloxacin | 2012 |
Bisacodyl rectal preparation can decrease infectious complications of transrectal ultrasound-guided prostate biopsy.
Topics: Adenocarcinoma; Administration, Oral; Administration, Rectal; Adult; Aged; Aged, 80 and over; Antibi | 2003 |
Epididymitis after transrectal ultrasound-guided needle biopsy of prostate gland.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Biopsy, Needle; Ciprofloxaci | 2004 |
Management of acute epididymitis: are European guidelines being followed?
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Chlamydia Infections; C | 2004 |
[Evaluation of 18 epididymo-orchitis cases].
Topics: Adolescent; Adult; Bacteriuria; Brucellosis; Doxycycline; Drug Therapy, Combination; Epididymitis; E | 1993 |
Comparative efficacies of ofloxacin, cefotaxime, and doxycycline for treatment of experimental epididymitis due to Escherichia coli in rats.
Topics: Animals; Cefotaxime; Doxycycline; Epididymitis; Escherichia coli; Escherichia coli Infections; Male; | 1993 |
National guideline for the management of epididymo-orchitis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases).
Topics: Anti-Bacterial Agents; Ceftriaxone; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Epididymitis; | 1999 |
Ofloxacin: a probable cause of toxic epidermal necrolysis.
Topics: Aged; Anti-Infective Agents; Epididymitis; Fatal Outcome; Humans; Male; Ofloxacin; Stevens-Johnson S | 2001 |
[Acute nongonococcal epididymitis--pharmacological and therapeutic aspects of levofloxacin].
Topics: Acute Disease; Administration, Oral; Adult; Chlamydia trachomatis; Epididymis; Epididymitis; Humans; | 1992 |
[Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis].
Topics: Adult; Aged; Chronic Disease; Drug Administration Schedule; Epididymitis; Escherichia coli; Humans; | 1992 |
[Initial therapy of acute unilateral epididymitis using ofloxacin. I. Clinical and microbiological findings].
Topics: Acute Disease; Adult; Bacterial Infections; Bacteriuria; Chlamydia trachomatis; Epididymitis; Follow | 1990 |
[Initial therapy of acute unilateral epididymitis using ofloxacin. II. Andrological findings].
Topics: Acute Disease; Adult; Epididymitis; Follicle Stimulating Hormone; Humans; Male; Middle Aged; Ofloxac | 1990 |
Epididymitis: aspects concerning etiology and treatment.
Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachomatis; Epididymitis; Humans; Mal | 1987 |
Acute nongonococcal epididymitis. Aetiological and therapeutic aspects.
Topics: Acute Disease; Adolescent; Adult; Aging; Anti-Infective Agents; Epididymitis; Humans; Male; Middle A | 1987 |