ofloxacin has been researched along with Enterocolitis, Pseudomembranous in 13 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Enterocolitis, Pseudomembranous: An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among hospitalized patients with diarrhea who underwent testing for C difficile toxin, age 75 years or older, hospitalization for 7 days or greater, and recent exposure to cefazolin or levofloxacin were important predictors of a positive CDTT." | 3.74 | Is it Clostridium difficile infection or something else? A case-control study of 352 hospitalized patients with new-onset diarrhea. ( Aradhyula, S; Greisnauer, S; Manian, FA; Meyer, PL; Senkel, D; Setzer, J; Wiechens, M, 2007) |
| "In this controlled before and after observational study, moxifloxacin chemoprophylaxis was used during prolonged neutropenia in haemato-oncological patients (period 2; 282 episodes)." | 3.73 | Moxifloxacin prophylaxis in neutropenic patients. ( Bommer, M; Döhner, H; Kern, P; Kern, WV; Marre, R; Reuter, S; Sigge, A; von Baum, H, 2006) |
| " Although very useful agents, the fluoroquinolones as a class are associated with a number of adverse events, some with considerable clinical significance." | 2.46 | Safety profile of the fluoroquinolones: focus on levofloxacin. ( Liu, HH, 2010) |
| "Patients who are treated for acute leukemia should be offered prophylaxis with ciprofloxacin or levofloxacin." | 2.43 | Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions. ( Bucaneve, G; Cullen, M; Fraser, A; Gafter-Gvili, A; Kern, WV; Leibovici, L; Paul, M, 2006) |
| "He had had recent chemotherapy for Merkel cell carcinoma of the right ear." | 1.34 | Use of intravenous immunoglobulin for the treatment of severe Clostridium difficile colitis. ( Hassoun, A; Ibrahim, F, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, HH | 1 |
| Kawaratani, H | 1 |
| Tsujimoto, T | 1 |
| Toyohara, M | 1 |
| Kin, K | 1 |
| Taniguchi, T | 1 |
| Shirai, Y | 1 |
| Ikenaka, Y | 1 |
| Nakayama, M | 1 |
| Fujii, H | 1 |
| Fukui, H | 1 |
| Muto, CA | 1 |
| Pokrywka, M | 1 |
| Shutt, K | 1 |
| Mendelsohn, AB | 1 |
| Nouri, K | 1 |
| Posey, K | 1 |
| Roberts, T | 1 |
| Croyle, K | 1 |
| Krystofiak, S | 1 |
| Patel-Brown, S | 1 |
| Pasculle, AW | 1 |
| Paterson, DL | 1 |
| Saul, M | 1 |
| Harrison, LH | 1 |
| von Baum, H | 1 |
| Sigge, A | 1 |
| Bommer, M | 1 |
| Kern, WV | 2 |
| Marre, R | 1 |
| Döhner, H | 1 |
| Kern, P | 1 |
| Reuter, S | 1 |
| Dhalla, IA | 1 |
| Mamdani, MM | 1 |
| Simor, AE | 1 |
| Kopp, A | 1 |
| Rochon, PA | 1 |
| Juurlink, DN | 1 |
| Leibovici, L | 1 |
| Paul, M | 1 |
| Cullen, M | 1 |
| Bucaneve, G | 1 |
| Gafter-Gvili, A | 1 |
| Fraser, A | 1 |
| Biller, P | 1 |
| Shank, B | 1 |
| Lind, L | 1 |
| Brennan, M | 1 |
| Tkatch, L | 1 |
| Killgore, G | 1 |
| Thompson, A | 1 |
| McDonald, LC | 1 |
| Hassoun, A | 1 |
| Ibrahim, F | 1 |
| Manian, FA | 1 |
| Aradhyula, S | 1 |
| Greisnauer, S | 1 |
| Senkel, D | 1 |
| Setzer, J | 1 |
| Wiechens, M | 1 |
| Meyer, PL | 1 |
| Yew, WW | 1 |
| Chau, CH | 1 |
| Wen, KH | 1 |
| Roblin, X | 1 |
| Baudry, C | 1 |
| Becot, F | 1 |
| Abidaner, J | 1 |
| Monnet, D | 1 |
| Dan, M | 1 |
| Samra, Z | 1 |
| Tacke, W | 1 |
| Hausmann, L | 1 |
4 reviews available for ofloxacin and Enterocolitis, Pseudomembranous
| Article | Year |
|---|---|
Safety profile of the fluoroquinolones: focus on levofloxacin.
Topics: Adult; Aged, 80 and over; Anti-Bacterial Agents; Cardiovascular Diseases; Central Nervous System Dis | 2010 |
Pseudomembranous colitis complicating ulcerative colitis.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Colitis, Ulcerative; Colonoscopy; Enterocolit | 2010 |
Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions.
Topics: Acute Disease; Antibiotic Prophylaxis; Antineoplastic Agents; Bone Marrow Transplantation; Ciproflox | 2006 |
[Pseudomembraneous colitis following antibiotic administration--a diagnostic and therapeutic challenge].
Topics: Aged; Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Female; Humans; Intestinal Mucosa; Mid | 1988 |
9 other studies available for ofloxacin and Enterocolitis, Pseudomembranous
| Article | Year |
|---|---|
A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use.
Topics: Anti-Bacterial Agents; Case-Control Studies; Cause of Death; Clindamycin; Clostridioides difficile; | 2005 |
Moxifloxacin prophylaxis in neutropenic patients.
Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Bacteremia; Clostridioides difficile; | 2006 |
Are broad-spectrum fluoroquinolones more likely to cause Clostridium difficile-associated disease?
Topics: Aged; Aged, 80 and over; Aza Compounds; Case-Control Studies; Clostridioides difficile; Enterocoliti | 2006 |
Moxifloxacin therapy as a risk factor for Clostridium difficile-associated disease during an outbreak: attempts to control a new epidemic strain.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Clostridioides difficile; Cross I | 2007 |
Use of intravenous immunoglobulin for the treatment of severe Clostridium difficile colitis.
Topics: Aged; Anti-Bacterial Agents; Carcinoma, Merkel Cell; Clostridioides difficile; Cytotoxins; Diarrhea; | 2007 |
Is it Clostridium difficile infection or something else? A case-control study of 352 hospitalized patients with new-onset diarrhea.
Topics: Aged; Analysis of Variance; Case-Control Studies; Cefazolin; Ceftriaxone; Clostridioides difficile; | 2007 |
Pseudomembranous colitis in a patient treated with ofloxacin for tuberculosis.
Topics: Aged; Antitubercular Agents; Enterocolitis, Pseudomembranous; Humans; Male; Ofloxacin; Tuberculosis, | 1996 |
[Pseudomembranous colitis caused by ofloxacin].
Topics: Enterocolitis, Pseudomembranous; Humans; Male; Ofloxacin | 1990 |
Clostridium difficile colitis associated with ofloxacin therapy.
Topics: Aged; Clostridium; Enterocolitis, Pseudomembranous; Humans; Male; Ofloxacin | 1989 |