Page last updated: 2024-11-01

ofloxacin and Enterobacteriaceae Infections

ofloxacin has been researched along with Enterobacteriaceae Infections in 20 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Enterobacteriaceae Infections: Infections with bacteria of the family ENTEROBACTERIACEAE.

Research Excerpts

ExcerptRelevanceReference
"The objective of this open-label, single-arm, multicenter study was to assess the efficacy and safety of levofloxacin in the treatment of complicated urinary tract infections."9.10[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections]. ( Marchetti, F; Trinchieri, A, 2003)
"Comparison of efficacy and safety of sparfloxacin vs ofloxacin for treatment of acute bacterial exacerbations of chronic bronchitis (ABECB)."9.08Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group. ( Bensch, G; Chodosh, S; DeAbate, CA; Harper, L; Henry, D; Jubran, A; Talbot, GH; Tipping, D, 1998)
"The objective of this open-label, single-arm, multicenter study was to assess the efficacy and safety of levofloxacin in the treatment of complicated urinary tract infections."5.10[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections]. ( Marchetti, F; Trinchieri, A, 2003)
"Comparison of efficacy and safety of sparfloxacin vs ofloxacin for treatment of acute bacterial exacerbations of chronic bronchitis (ABECB)."5.08Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group. ( Bensch, G; Chodosh, S; DeAbate, CA; Harper, L; Henry, D; Jubran, A; Talbot, GH; Tipping, D, 1998)
" It was used alone 26 times and on 6 occasions it was associated with rifampin on 6 staphylococcal infections."3.67[Ofloxacin (RU 43280). Clinical study]. ( Bertrand, A; Despaux, E; Janbon, F; Jonquet, O; Reynes, J, 1987)
"The empiric treatment of acute pyelonephritis (APN) with third generation cephalosporins (3GC) or fluoroquinolones (FQ) has been challenged by Escherichia coli resistance reported by community surveillance networks."1.40Antibiotic resistance in adult female patients hospitalized for acute pyelonephritis: rates and predicting factors. ( Caron, F; Choplin-Renard, J; Etienne, M; Pestel-Caron, M; Van Elslande, H, 2014)
"A 55 year-old male patient with chronic renal failure was hospitalized in intensive care unit following cardiopulmonary arrest."1.38[A case of ventilator-associated pneumonia due to Pantoea agglomerans]. ( Altın, N; Argun, C; Canbakan, B; Cesur, S; Koldaş, K; Kurşun, O; Sencan, I; Unal, N, 2012)
"Cellulitis is usually caused by organisms such as beta-hemolytic streptococci and Staphylococcus aureus."1.32Sepsis in a renal transplant recipient due to Citrobacter braakii. ( Agraharkar, ML; Gupta, R; Rauf, SJ; Singh, S; Smith, J, 2003)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's6 (30.00)18.2507
2000's4 (20.00)29.6817
2010's7 (35.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Quiroga, MP1
Andres, P1
Petroni, A1
Soler Bistué, AJ1
Guerriero, L1
Vargas, LJ1
Zorreguieta, A1
Tokumoto, M1
Quiroga, C1
Tolmasky, ME1
Galas, M1
Centrón, D1
Lecuru, M1
Daniau, C1
Alfandari, S1
Dumartin, C1
Bajolet, O1
Blanchard, H1
Simon, L1
Colomb-Cotinat, M1
Etienne, M1
Van Elslande, H1
Choplin-Renard, J1
Pestel-Caron, M1
Caron, F1
Rocke, J1
Roydhouse, T1
Spencer, T1
Zhang, J1
Ye, LP1
Li, W1
Shen, LY1
Salman, S1
Young, M1
Van Sickels, JE1
Shao, Y1
Xiong, Z1
Li, X1
Hu, L1
Shen, J1
Li, T1
Hu, F1
Chen, S1
Kurşun, O1
Unal, N1
Cesur, S1
Altın, N1
Canbakan, B1
Argun, C1
Koldaş, K1
Sencan, I1
Toh, HS1
Chuang, YC1
Huang, CC1
Lee, YL1
Liu, YM1
Ho, CM1
Lu, PL1
Liu, CE1
Chen, YH1
Wang, JH1
Ko, WC1
Yu, KW1
Liu, YC1
Chen, YS1
Tang, HJ1
Hsueh, PR1
Trinchieri, A1
Marchetti, F1
Gupta, R1
Rauf, SJ1
Singh, S1
Smith, J1
Agraharkar, ML1
Liang, YJ1
Zhai, XB1
He, LX1
Guo, ZL1
Ren, T1
He, ZG1
Zhang, L1
Zheng, YH1
Fukuyama, M1
Kawakami, K1
Suda, O1
Imagawa, Y1
Gentry, LO1
Rodriguez-Gomez, G1
DeAbate, CA1
Henry, D1
Bensch, G1
Jubran, A1
Chodosh, S1
Harper, L1
Tipping, D1
Talbot, GH1
Dekitsch, C1
Schein, R1
Markopulos, E1
Kuen, B1
Graninger, W1
Georgopoulos, A1
Steward, CD1
Stocker, SA1
Swenson, JM1
O'Hara, CM1
Edwards, JR1
Gaynes, RP1
McGowan, JE1
Tenover, FC1
Liassine, N1
Chelfi, A1
Rahal, K1
Bertrand, A1
Janbon, F1
Despaux, E1
Jonquet, O1
Reynes, J1
Bernard, E1
Etesse, H1
Garraffo, R1
Giaume, F1
Dellamonica, P1

Trials

3 trials available for ofloxacin and Enterobacteriaceae Infections

ArticleYear
[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2003, Volume: 75, Issue:1

    Topics: Anti-Infective Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Enterobacteriaceae

2003
Ofloxacin treatment of difficult infections of the skin and skin structure.
    Cutis, 1993, Volume: 51, Issue:1

    Topics: Abscess; Administration, Oral; Adult; Aged; Aged, 80 and over; Cellulitis; Drug Administration Sched

1993
Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group.
    Chest, 1998, Volume: 114, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Chlamy

1998

Other Studies

17 other studies available for ofloxacin and Enterobacteriaceae Infections

ArticleYear
Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Alleles; Amino Acid Sequence; Argentina; Bacterial Proteins; Base Sequence; beta-Lactamases; Cross I

2007
Evolution of antibiotic treatments for healthcare-associated infections caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae in France.
    Infectious diseases now, 2022, Volume: 52, Issue:7

    Topics: Aminoglycosides; Amoxicillin; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Cla

2022
Antibiotic resistance in adult female patients hospitalized for acute pyelonephritis: rates and predicting factors.
    Medecine et maladies infectieuses, 2014, Volume: 44, Issue:5

    Topics: Acute Disease; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacteremia; Catchment Area, Heal

2014
Canaliculitis caused by Citrobacter freundii.
    Clinical & experimental ophthalmology, 2016, Volume: 44, Issue:9

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Canaliculitis; Cefazolin; Citrobacter freundii; Combined M

2016
Iatrogenic gastric wall abscess infected with Enterobacter cloacae after biopsy.
    Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Diagnosis, Differential; Drug Therapy, Comb

2010
Osteomyelitis after bilateral sagittal split osteotomy: case report and a review of the management.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2011, Volume: 111, Issue:4

    Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Bone Plates; Bone Screws; Clindamycin; Drainage; Enterob

2011
Prevalence of plasmid-mediated quinolone resistance determinants in Citrobacter freundii isolates from Anhui province, PR China.
    Journal of medical microbiology, 2011, Volume: 60, Issue:Pt 12

    Topics: China; Ciprofloxacin; Citrobacter freundii; Conjugation, Genetic; Drug Resistance, Bacterial; Entero

2011
[A case of ventilator-associated pneumonia due to Pantoea agglomerans].
    Mikrobiyoloji bulteni, 2012, Volume: 46, Issue:2

    Topics: Anti-Bacterial Agents; Cefoperazone; Cross Infection; Drug Therapy, Combination; Enterobacteriaceae

2012
Antimicrobial susceptibility profiles of Gram-negative bacilli isolated from patients with hepatobiliary infections in Taiwan: results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2006-2010.
    International journal of antimicrobial agents, 2012, Volume: 40 Suppl

    Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftazidime; Ciprofloxacin; Drug Resistance, Bacterial; Ente

2012
Sepsis in a renal transplant recipient due to Citrobacter braakii.
    Southern medical journal, 2003, Volume: 96, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Bacteremia; Cellulitis; Citrobacter freundi

2003
Research and clinical value of antibacterial-application software.
    Chinese medical journal, 2008, Jan-05, Volume: 121, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Enterobacter cloaca

2008
[In vitro antibacterial activity of balofloxacin (BLFX) against isolates from patients with bacterial enteritis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1995, Volume: 69, Issue:9

    Topics: Anti-Infective Agents; Drug Resistance, Microbial; Enteritis; Enterobacteriaceae Infections; Escheri

1995
Analysis of mutations to gyrA in quinolone-resistant clinical isolates of Enterobacter cloacae.
    Journal of medical microbiology, 1999, Volume: 48, Issue:1

    Topics: Amino Acid Substitution; Anti-Infective Agents; Ciprofloxacin; Codon; Deoxyribonucleases, Type II Si

1999
Comparison of agar dilution, disk diffusion, MicroScan, and Vitek antimicrobial susceptibility testing methods to broth microdilution for detection of fluoroquinolone-resistant isolates of the family Enterobacteriaceae.
    Journal of clinical microbiology, 1999, Volume: 37, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; Culture Media; Drug Resistance, Microbial; Enterobacteriaceae;

1999
[Resistance to new quinolones among the enterobacteria].
    Archives de l'Institut Pasteur d'Algerie. Institut Pasteur d'Algerie, 1992, Volume: 58

    Topics: Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Nalidixic Aci

1992
[Ofloxacin (RU 43280). Clinical study].
    Pathologie-biologie, 1987, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Drug Therapy, Combination; Enterobacteriaceae Infect

1987
[Bone infections: treatment by ofloxacin. Apropos of 10 cases].
    Pathologie-biologie, 1987, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Enterobacteriaceae Infections;

1987