Page last updated: 2024-11-01

ofloxacin and Enteritis

ofloxacin has been researched along with Enteritis in 5 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Enteritis: Inflammation of any segment of the SMALL INTESTINE.

Research Excerpts

ExcerptRelevanceReference
"Eradication of non-typhoid salmonellae was evaluated in a randomized, double-blinded study of 49 patients with acute enteritis after therapy with ofloxacin 400 mg once daily for 5 or 10 days."9.09Eradication of non-typhoid salmonellae in acute enteritis after therapy with ofloxacin for 5 or 10 days. ( Digranes, A; Halstensen, A; Langeland, N; Peterson, LE; Rolstad, T; Solberg, CO; Voltersvik, P, 2000)
"The clinical efficacy, safety and usefulness of Rokitamycin (RKM), a new macrolide antibiotic, were compared with those of Ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double blind method."9.07[Comparison of clinical efficacy of rokitamycin (RKM) and ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double-blind method. The Research Committee for the Effect of Rokitamycin, Research Group for Infectious Enteritis]. ( Machii, A; Nitta, Y; Obana, M; Ota, S; Sagara, H; Sato, J; Seo, T; Takizawa, Y; Tomizawa, I; Tsunoda, T, 1991)
"Eradication of non-typhoid salmonellae was evaluated in a randomized, double-blinded study of 49 patients with acute enteritis after therapy with ofloxacin 400 mg once daily for 5 or 10 days."5.09Eradication of non-typhoid salmonellae in acute enteritis after therapy with ofloxacin for 5 or 10 days. ( Digranes, A; Halstensen, A; Langeland, N; Peterson, LE; Rolstad, T; Solberg, CO; Voltersvik, P, 2000)
"The clinical efficacy, safety and usefulness of Rokitamycin (RKM), a new macrolide antibiotic, were compared with those of Ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double blind method."5.07[Comparison of clinical efficacy of rokitamycin (RKM) and ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double-blind method. The Research Committee for the Effect of Rokitamycin, Research Group for Infectious Enteritis]. ( Machii, A; Nitta, Y; Obana, M; Ota, S; Sagara, H; Sato, J; Seo, T; Takizawa, Y; Tomizawa, I; Tsunoda, T, 1991)
"We determined the minimum inhibitory concentration (MIC) of DR-3355, a newly developed quinolone-derivative antibacterial agent, against clinical isolates of various bacterial species from enteritis patients, and compared them with those of ofloxacin (OFLX), ciprofloxacin (CPFX), nalidixic acid (NA), ampicillin (ABPC), kanamycin (KM)."3.68[In vitro antimicrobial activity of DR-3355, a new quinolone antibacterial agent, against clinical isolates of enteritis-causing bacteria]. ( Horiuchi, S; Inagaki, Y; Nakaya, R; Ogawa, M; Yamamoto, N, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fukuyama, M2
Kawakami, K1
Suda, O1
Imagawa, Y1
Voltersvik, P1
Halstensen, A1
Langeland, N1
Digranes, A1
Peterson, LE1
Rolstad, T1
Solberg, CO1
Furuhata, K1
Oonaka, K1
Hara, T1
Sunakawa, K1
Horiuchi, S1
Inagaki, Y1
Yamamoto, N1
Ogawa, M1
Nakaya, R1
Obana, M1
Tomizawa, I1
Takizawa, Y1
Nitta, Y1
Sagara, H1
Seo, T1
Sato, J1
Tsunoda, T1
Ota, S1
Machii, A1

Trials

2 trials available for ofloxacin and Enteritis

ArticleYear
Eradication of non-typhoid salmonellae in acute enteritis after therapy with ofloxacin for 5 or 10 days.
    The Journal of antimicrobial chemotherapy, 2000, Volume: 46, Issue:3

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Double-Blind Method; Enteritis; Humans; Middle Ag

2000
[Comparison of clinical efficacy of rokitamycin (RKM) and ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double-blind method. The Research Committee for the Effect of Rokitamycin, Research Group for Infectious Enteritis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1991, Volume: 65, Issue:9

    Topics: Adolescent; Adult; Aged; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Double-

1991

Other Studies

3 other studies available for ofloxacin and Enteritis

ArticleYear
[In vitro antibacterial activity of balofloxacin (BLFX) against isolates from patients with bacterial enteritis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1995, Volume: 69, Issue:9

    Topics: Anti-Infective Agents; Drug Resistance, Microbial; Enteritis; Enterobacteriaceae Infections; Escheri

1995
[Antibacterial activity of fosfomycin against the causative bacteria isolated from bacterial enteritis].
    The Japanese journal of antibiotics, 2000, Volume: 53, Issue:7

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Blood; Campylobacter; Electrolyt

2000
[In vitro antimicrobial activity of DR-3355, a new quinolone antibacterial agent, against clinical isolates of enteritis-causing bacteria].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1992, Volume: 66, Issue:1

    Topics: Bacteria; Enteritis; Microbial Sensitivity Tests; Ofloxacin

1992