Page last updated: 2024-11-01

ofloxacin and Endotoxin Shock

ofloxacin has been researched along with Endotoxin Shock in 10 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"Leptospirosis and scrub typhus are common zoonoses and coinfection with both diseases has been reported sporadically, particularly in tropical and subtropical areas."5.38Successful treatment of septic shock and respiratory failure due to leptospirosis and scrub typhus coinfection with penicillin, levofloxacin, and activated protein C. ( Chiu, CT; Lai, CH; Lai, YF; Lin, HH; Wei, YF, 2012)
"Leptospirosis and scrub typhus are common zoonoses and coinfection with both diseases has been reported sporadically, particularly in tropical and subtropical areas."1.38Successful treatment of septic shock and respiratory failure due to leptospirosis and scrub typhus coinfection with penicillin, levofloxacin, and activated protein C. ( Chiu, CT; Lai, CH; Lai, YF; Lin, HH; Wei, YF, 2012)
"He suddenly fell into septic shock about 12 hours after the biopsy."1.36[Septic shock due to fluoroquinolone-resistant Escherichia coli after trans-rectal prostate needle biopsy]. ( Fujishima, Y; Kato, R; Matsuura, T; Obara, W; Sato, K; Shimaya, R; Suzuki, Y; Tokiwa, S, 2010)
"pneumoniae serotype K1, complicated by septic shock and multiple organ dysfunction."1.35Rapidly fatal bacteremic pneumonia caused by Klebsiella pneumoniae with K1 hypermucoviscosity phenotype in a previously healthy young man receiving levofloxacin treatment. ( Chi, CL; Chuang, TY; Hsueh, PR; Lee, SW; Lin, CJ; Lin, TL; Liu, AY; Wang, JT, 2009)
"A 70-year-old man was hospitalized for septic shock with acute respiratory and renal failure after intravesical instillation of BCG, which was identified in the gastric aspiration sample."1.33[Acute respiratory failure and septic shock induced by Mycobacterium bovis. A rare side effect of intravesical BCG therapy]. ( Dequin, PF; Garot, D; Legras, A; Mercier, E; Narciso, B; Perrotin, D; Rival, G, 2006)
"The efficacy of two polymyxin-like peptides, KFFKFFKFF and IKFLKFLKFL, alone and combined with levofloxacin, was investigated in a rat model of septic shock."1.31Therapeutic efficacy of intraperitoneal polymyxin B and polymyxin-like peptides alone or combined with levofloxacin in rat models of septic shock. ( Cirioni, O; Ghiselli, R; Giacometti, A; Kamysz, W; Kasprzykowski, F; Mackiewicz, Z; Mocchegiani, F; Orlando, F; Paggi, AM; Saba, V; Scalise, G, 2002)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's5 (50.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, WS1
Ou, TY1
Chen, FL1
Hsu, CW1
Jean, SS1
BĂ©raud, G1
Iba Ba, J1
Legout, L1
Senneville, E1
Yazdanpanah, Y1
Mouton, Y1
Chuang, TY2
Lin, CJ2
Chi, CL1
Liu, AY1
Lee, SW2
Lin, TL1
Wang, JT1
Hsueh, PR2
Kato, R1
Suzuki, Y1
Matsuura, T1
Sato, K1
Shimaya, R1
Fujishima, Y1
Tokiwa, S1
Obara, W1
Wei, YF1
Chiu, CT1
Lai, YF1
Lai, CH1
Lin, HH1
Chuang, CP1
Jong, YS1
Chen, WJ1
Amoureux, MC1
Rajapakse, N1
Hegyi, E1
Le, D1
Grandics, P1
Szathmary, S1
Rival, G1
Garot, D1
Mercier, E1
Narciso, B1
Legras, A1
Perrotin, D1
Dequin, PF1
Giacometti, A1
Cirioni, O1
Ghiselli, R1
Mocchegiani, F1
Paggi, AM1
Orlando, F1
Kamysz, W1
Kasprzykowski, F1
Mackiewicz, Z1
Scalise, G1
Saba, V1
Miragliotta, G1

Other Studies

10 other studies available for ofloxacin and Endotoxin Shock

ArticleYear
Co-infection with Orientia tsutsugamushi and Mycoplasma pneumoniae in a traveler.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2015, Volume: 48, Issue:1

    Topics: Humans; Leptospirosis; Levofloxacin; Male; Ofloxacin; Penicillins; Protein C; Respiratory Insufficie

2015
[Primary Salmonella vascular graft infection and conservative treatment].
    Medecine et maladies infectieuses, 2008, Volume: 38, Issue:12

    Topics: Aged; Amikacin; Anti-Bacterial Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Blood Vessel Pr

2008
Rapidly fatal bacteremic pneumonia caused by Klebsiella pneumoniae with K1 hypermucoviscosity phenotype in a previously healthy young man receiving levofloxacin treatment.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2009, Volume: 42, Issue:5

    Topics: Anti-Bacterial Agents; Antigens, Bacterial; Bacteremia; Bacterial Capsules; Bacterial Typing Techniq

2009
[Septic shock due to fluoroquinolone-resistant Escherichia coli after trans-rectal prostate needle biopsy].
    Hinyokika kiyo. Acta urologica Japonica, 2010, Volume: 56, Issue:8

    Topics: Biopsy, Needle; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; L

2010
Successful treatment of septic shock and respiratory failure due to leptospirosis and scrub typhus coinfection with penicillin, levofloxacin, and activated protein C.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2012, Volume: 45, Issue:3

    Topics: Anti-Infective Agents; Antibodies, Bacterial; Humans; Leptospira; Leptospirosis; Levofloxacin; Male;

2012
Rapidly fatal community-acquired pneumonia due to Klebsiella pneumoniae complicated with acute myocarditis and accelerated idioventricular rhythm.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2012, Volume: 45, Issue:4

    Topics: Accelerated Idioventricular Rhythm; Acidosis, Lactic; Acute Disease; Community-Acquired Infections;

2012
Endotoxin removal from whole blood by a novel adsorption resin: efficiency and hemocompatibility.
    The International journal of artificial organs, 2004, Volume: 27, Issue:6

    Topics: Adsorption; Anti-Infective Agents; Blood Coagulation Factors; Cell Count; Chromatography, Affinity;

2004
[Acute respiratory failure and septic shock induced by Mycobacterium bovis. A rare side effect of intravesical BCG therapy].
    Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:6 Pt 1

    Topics: Acute Disease; Administration, Intravesical; Aged; Anti-Bacterial Agents; BCG Vaccine; Ceftriaxone;

2006
Therapeutic efficacy of intraperitoneal polymyxin B and polymyxin-like peptides alone or combined with levofloxacin in rat models of septic shock.
    The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Disease Models, Animal; Drug Therapy, Combina

2002
Endotoxin release after antibiotic treatment and its potential pathogenetic role in coagulative disorders of patients with gram-negative sepsis.
    Journal of chemotherapy (Florence, Italy), 1991, Volume: 3 Suppl 1

    Topics: Anti-Infective Agents; Blood Coagulation Disorders; Endotoxins; Humans; Norfloxacin; Ofloxacin; Salm

1991