ofloxacin has been researched along with Endocarditis, Bacterial in 31 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Endocarditis, Bacterial: Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to compare the therapeutic efficacy of quinupristin-dalfopristin (QD) alone, or in combination with gentamicin (G), teicoplanin (T), imipenem (I) or levofloxacin (L) against a strain of multidrug-resistant E." | 1.33 | [Comparative study of treatment with quinupristin-dalfopristin alone or in combination with gentamicin, teicoplanin, imipenem or levofloxacin in experimental endocarditis due to a multidrug-resistant Enterococcus faecium]. ( Gómez Gómez, J; López Fornás, F; Lorente Salinas, I; Martínez García, F; Pérez Salmerón, J; Roldán Conesa, D; Ruiz Gómez, J; Segovia Hernández, M; Valdés Chávarri, M, 2006) |
| "Levofloxacin was no more effective than penicillin against the penicillin-resistant strain." | 1.30 | Efficacy of levofloxacin for experimental aortic-valve endocarditis in rabbits infected with viridans group streptococcus or Staphylococcus aureus. ( Chambers, HF; Chow, LL; Hackbarth, C; Xiang, Q, 1999) |
| "Levofloxacin was investigated against viridans group streptococci in vitro and in rats with experimental aortic endocarditis." | 1.30 | Efficacy of levofloxacin in the treatment of experimental endocarditis caused by viridans group streptococci. ( Caldelari, I; Entenza, JM; Glauser, MP; Moreillon, P, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.45) | 18.7374 |
| 1990's | 9 (29.03) | 18.2507 |
| 2000's | 15 (48.39) | 29.6817 |
| 2010's | 5 (16.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saidane, O | 1 |
| Mahmoud, I | 1 |
| Saadi, F | 1 |
| Souayah, A | 1 |
| Zouari, R | 1 |
| Bhagan-Bruno, S | 1 |
| Lather, N | 1 |
| Fergus, IV | 1 |
| Batard, E | 1 |
| Jamme, F | 1 |
| Villette, S | 1 |
| Jacqueline, C | 1 |
| de la Cochetière, MF | 1 |
| Caillon, J | 1 |
| Réfrégiers, M | 1 |
| Samuel, V | 1 |
| Bajwa, AA | 1 |
| Cury, JD | 1 |
| Fukuta, Y | 1 |
| Yildiz-Aktas, IZ | 1 |
| William Pasculle, A | 1 |
| Veldkamp, PJ | 1 |
| Karachalios, G | 1 |
| Bablekos, G | 1 |
| Karachaliou, G | 1 |
| Charalabopoulos, AK | 1 |
| Charalabopoulos, K | 1 |
| Candel, FJ | 1 |
| López, R | 1 |
| Valdivia, A | 1 |
| Núñez, MJ | 1 |
| Roca-Arbonés, V | 1 |
| Picazo de la Garza, JJ | 1 |
| Almeda, FQ | 1 |
| Tenorio, AR | 1 |
| Barkatullah, S | 1 |
| Parrillo, JE | 1 |
| Simon, DM | 1 |
| Entenza, JM | 3 |
| Vouillamoz, J | 2 |
| Glauser, MP | 3 |
| Moreillon, P | 3 |
| Medford, AR | 1 |
| Patel, MC | 1 |
| Levi, MH | 1 |
| Mahadevi, P | 1 |
| Nana, M | 1 |
| Merav, AD | 1 |
| Robbins, N | 1 |
| Healy, B | 1 |
| Llewelyn, M | 1 |
| Westmoreland, D | 1 |
| Lloyd, G | 1 |
| Brown, N | 1 |
| Pérez Salmerón, J | 1 |
| Martínez García, F | 1 |
| Roldán Conesa, D | 1 |
| Lorente Salinas, I | 1 |
| López Fornás, F | 1 |
| Ruiz Gómez, J | 1 |
| Gómez Gómez, J | 1 |
| Segovia Hernández, M | 1 |
| Valdés Chávarri, M | 1 |
| Fradi, I | 1 |
| Drissa, MA | 1 |
| Cheour, M | 1 |
| Drissa, H | 1 |
| Foo, SS | 1 |
| Lye, DC | 1 |
| Aepinus, C | 1 |
| Adolph, E | 1 |
| von Eiff, C | 1 |
| Podbielski, A | 1 |
| Petzsch, M | 1 |
| Ruotsalainen, E | 1 |
| Kardén-Lilja, M | 1 |
| Kuusela, P | 1 |
| Vuopio-Varkila, J | 1 |
| Virolainen-Julkunen, A | 1 |
| Sarna, S | 1 |
| Valtonen, V | 1 |
| Järvinen, A | 1 |
| Fernández Guerrero, ML | 1 |
| Torres Perea, R | 1 |
| Verdejo Morcillo, C | 1 |
| Fernández Roblas, R | 1 |
| de Górgolas, M | 1 |
| Kaplanski, G | 1 |
| Granel, B | 1 |
| Vaz, T | 1 |
| Durand, JM | 1 |
| Raoult, D | 1 |
| Houpikian, P | 1 |
| Tissot Dupont, H | 1 |
| Riss, JM | 1 |
| Arditi-Djiane, J | 1 |
| Brouqui, P | 1 |
| Chambers, HF | 1 |
| Xiang, Q | 1 |
| Chow, LL | 1 |
| Hackbarth, C | 1 |
| Ying, W | 1 |
| Nguyen, MQ | 1 |
| Jahre, JA | 1 |
| Caldelari, I | 1 |
| Guttigoli, A | 1 |
| Zaman, MM | 1 |
| Sailler, L | 1 |
| Marchou, B | 1 |
| Lemozy, J | 1 |
| Bonnet, E | 1 |
| Elias, Z | 1 |
| Cuzin, L | 1 |
| Massip, P | 1 |
| Flannery, MT | 1 |
| Le, M | 1 |
| Altus, P | 1 |
| Göker, K | 1 |
| Güvener, O | 1 |
| Kaatz, GW | 1 |
| Seo, SM | 1 |
| Barriere, SL | 1 |
| Albrecht, LM | 1 |
| Rybak, MJ | 1 |
| Raffi, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Trial Evaluating Safety and Efficacy of Hydroxychloroquine and Nitazoxanide Combination as Adjuvant Therapy in Covid-19 Newly Diagnosed Egyptian Patients: A Tanta University Hope[NCT04361318] | Phase 2/Phase 3 | 100 participants (Anticipated) | Interventional | 2020-05-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for ofloxacin and Endocarditis, Bacterial
| Article | Year |
|---|---|
Legionella micdadei prosthetic valve endocarditis complicated by brain abscess: case report and review of the literature.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteriological Techniques; Brain; Brain Abscess; Echocardiograp | 2012 |
[Endocarditis due to Stenotrophomonas maltophilia].
Topics: Aortic Valve Insufficiency; Disease Susceptibility; Drug Resistance, Multiple, Bacterial; Drug Thera | 2002 |
L. micdadei PVE successfully treated with levofloxacin/valve replacement: case report and review of the literature.
Topics: Anti-Bacterial Agents; Bioprosthesis; Device Removal; Endocarditis, Bacterial; Heart Valve Prosthesi | 2005 |
1 trial available for ofloxacin and Endocarditis, Bacterial
| Article | Year |
|---|---|
Methicillin-sensitive Staphylococcus aureus bacteraemia and endocarditis among injection drug users and nonaddicts: host factors, microbiological and serological characteristics.
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Case-Control Studies; Electro | 2008 |
27 other studies available for ofloxacin and Endocarditis, Bacterial
| Article | Year |
|---|---|
[Spondylodiscitis and Lactococcus cremoris endocarditis].
Topics: Aged; Animals; Anti-Bacterial Agents; Bacteremia; Braces; Cattle; Combined Modality Therapy; Disciti | 2013 |
Acinetobacter endocarditis presenting as a large right atrial mass: an atypical presentation.
Topics: Acinetobacter Infections; Adult; Anti-Bacterial Agents; Catheters, Indwelling; Cefepime; Cephalospor | 2010 |
Diffusion of ofloxacin in the endocarditis vegetation assessed with synchrotron radiation UV fluorescence microspectroscopy.
Topics: Animals; Anti-Bacterial Agents; Diffusion; Endocarditis, Bacterial; Heart Valves; Image Processing, | 2011 |
First case of Legionella pneumophila native valve endocarditis.
Topics: Adult; Aortic Valve; Community-Acquired Infections; Endocarditis, Bacterial; Female; Humans; Immunos | 2011 |
Infectious endocarditis due to Yersinia enterocolitica.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Therapy, Combination; Endocarditis, Bacterial; Hu | 2002 |
Infective endocarditis due to Haemophilus aphrophilus treated with levofloxacin.
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Echocardiography, Transesophageal; E | 2002 |
Efficacy of garenoxacin in treatment of experimental endocarditis due to Staphylococcus aureus or viridans group streptococci.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; En | 2004 |
Case 29-2004: a woman with acute onset of chest pain and fever.
Topics: Aged; Anti-Bacterial Agents; Blood; Chest Pain; Diagnosis, Differential; Endocarditis, Bacterial; Fe | 2005 |
The value of follow-up after acute Q fever infection.
Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Chronic Disease; Complement Fixation Tests; Coxiella b | 2006 |
[Comparative study of treatment with quinupristin-dalfopristin alone or in combination with gentamicin, teicoplanin, imipenem or levofloxacin in experimental endocarditis due to a multidrug-resistant Enterococcus faecium].
Topics: Aged; Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; | 2006 |
[Q fever endocarditis: a case report].
Topics: Adult; Anti-Bacterial Agents; Aortic Valve; Aortic Valve Stenosis; Doxycycline; Drug Therapy, Combin | 2006 |
Methicillin-sensitive Staphylococcus aureus tricuspid valve endocarditis with annular abscess cured with oral levofloxacin and rifampicin.
Topics: Abscess; Adult; Anti-Bacterial Agents; Cloxacillin; Endocarditis, Bacterial; Fever; Humans; Levoflox | 2007 |
Kytococcus schroeteri: a probably underdiagnosed pathogen involved in prosthetic valve endocarditis.
Topics: Actinomycetales; Actinomycetales Infections; Adult; Aortic Valve Insufficiency; DNA, Bacterial; Drug | 2008 |
Treatment of experimental endocarditis due to ampicillin-susceptible or ampicillin-resistant Salmonella enteritidis.
Topics: Ampicillin; Ampicillin Resistance; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime | 1996 |
Levofloxacin versus ciprofloxacin, flucloxacillin, or vancomycin for treatment of experimental endocarditis due to methicillin-susceptible or -resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Endocarditis, Bacterial; Floxa | 1997 |
Jarisch-Herxheimer reaction complicating the treatment of chronic Q fever endocarditis: elevated TNFalpha and IL-6 serum levels.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chronic Disease; Coxiella burnetii; Doxycycline; Drug | 1998 |
Treatment of Q fever endocarditis: comparison of 2 regimens containing doxycycline and ofloxacin or hydroxychloroquine.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Doxycycline; Drug Therapy, Combination; Endocar | 1999 |
Efficacy of levofloxacin for experimental aortic-valve endocarditis in rabbits infected with viridans group streptococcus or Staphylococcus aureus.
Topics: Animals; Aortic Valve; Drug Resistance, Microbial; Endocarditis, Bacterial; Heart Valve Diseases; Le | 1999 |
Brucella canis endocarditis: case report.
Topics: Brucella; Brucellosis; Doxycycline; Drug Therapy, Combination; Endocarditis, Bacterial; Female; Huma | 1999 |
Efficacy of levofloxacin in the treatment of experimental endocarditis caused by viridans group streptococci.
Topics: Animals; Anti-Infective Agents; Catheterization; Ceftriaxone; Ciprofloxacin; Endocarditis, Bacterial | 1999 |
Bacteremia and possible endocarditis caused by Moraxella phenylpyruvica.
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Cefotaxime; Cephalospor | 2000 |
Successful treatment of Actinobacillus actinomycetemcomitans endocarditis with ofloxacin.
Topics: Actinobacillus Infections; Aged; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents; Endoc | 2000 |
Endocarditis due to Salmonella.
Topics: Aged; Anti-Infective Agents; Cardiac Catheterization; Ceftriaxone; Cephalosporins; Combined Modality | 2001 |
Antibacterial effects of ofloxacin, clindamycin and sultamicillin on surgical removal of impacted third molars.
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Bacteremia; Clindamycin; Dental Care for Disabled; Drug Th | 1992 |
Efficacy of ofloxacin in experimental Staphylococcus aureus endocarditis.
Topics: Animals; Drug Resistance, Microbial; Endocarditis, Bacterial; Female; Methicillin; Microbial Sensiti | 1990 |
Q-fever endocarditis.
Topics: Endocarditis, Bacterial; Female; Humans; Middle Aged; Ofloxacin; Pulmonary Fibrosis; Q Fever | 1989 |
[On behalf of the Austrian Cardiology Society we are publishing recommendations for the prevention of bacterial endocarditis. Issued by the Commission for Clinical Cardiology of the German Society of Cardiovascular Research].
Topics: Anti-Bacterial Agents; Clindamycin; Endocarditis, Bacterial; Humans; Ofloxacin; Oxazines; Penicillin | 1987 |