Page last updated: 2024-11-01

ofloxacin and Emphysema

ofloxacin has been researched along with Emphysema in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Emphysema: A pathological accumulation of air in tissues or organs.

Research Excerpts

ExcerptRelevanceReference
"Two different oral ofloxacin regimens, daily single-dose treatment with 200 mg (Regimen I) and every two week multidose treatment with 3 x 200 mg/day (Regimen II), were compared to evaluate the efficacy of quinolone regimens in controlling acute exacerbations of chronic respiratory tract infections."5.07Once daily versus every two week multidose ofloxacin in patients with acute exacerbations of chronic respiratory disease. ( Watanabe, A, 1991)
"A 59-year-old Japanese man who was receiving theophylline for emphysema experienced stimulation, insomnia, and tachycardia due to theophylline toxicity after clarithromycin and levofloxacin were added to the regimen."3.71Effect of levofloxacin on theophylline clearance during theophylline and clarithromycin combination therapy. ( Enomoto, H; Hasegawa, A; Kawana, H; Kitada, M; Kuriyama, T; Nakamura, H; Ohmori, S; Ohtsuka, T, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakamura, H1
Ohtsuka, T1
Enomoto, H1
Hasegawa, A1
Kawana, H1
Kuriyama, T1
Ohmori, S1
Kitada, M1
Watanabe, A1

Trials

1 trial available for ofloxacin and Emphysema

ArticleYear
Once daily versus every two week multidose ofloxacin in patients with acute exacerbations of chronic respiratory disease.
    Infection, 1991, Volume: 19 Suppl 7

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Bacterial Infections; Bronchiectasis; Bronchitis; Chr

1991

Other Studies

1 other study available for ofloxacin and Emphysema

ArticleYear
Effect of levofloxacin on theophylline clearance during theophylline and clarithromycin combination therapy.
    The Annals of pharmacotherapy, 2001, Volume: 35, Issue:6

    Topics: Anti-Infective Agents; Clarithromycin; Drug Interactions; Drug Therapy, Combination; Emphysema; Huma

2001