ofloxacin has been researched along with Electrolytes in 6 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a clinical trial including 17 multibacillary leprosy patients the in vivo effectiveness of ofloxacin on Mycobacterium leprae was tested via mass spectrometric determination of intrabacterial ratios of the concentrations of the sodium and potassium ions of individual organisms and of the ATP content per 10(6) bacteria isolated from skin biopsies." | 3.68 | Intrabacterial sodium-to-potassium ratios and ATP contents of Mycobacterium leprae from ofloxacin-treated patients. ( Dhople, AM; Dietz, M; Haas, M; Lindner, B; Seydel, U; Tebebe, YB, 1991) |
| " Due to the high antibiotic dosage requirement in anti-biofilm therapy, the most suitable formulation for this purpose is the antibiotic nanoparticles themselves, instead of the more extensively studied antibiotic-loaded nano-carriers, which often exhibit low drug loading." | 1.38 | Green preparation of antibiotic nanoparticle complex as potential anti-biofilm therapeutics via self-assembly amphiphile-polyelectrolyte complexation with dextran sulfate. ( Cheow, WS; Hadinoto, K, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahuja, M | 1 |
| Kumar, A | 1 |
| Wu, G | 1 |
| Chen, L | 1 |
| Li, H | 1 |
| Wang, YJ | 1 |
| Cheow, WS | 1 |
| Hadinoto, K | 1 |
| Arai, T | 1 |
| Ichinose, M | 1 |
| Kuroda, H | 1 |
| Nimura, N | 1 |
| Kinoshita, T | 1 |
| Fukuyama, M | 1 |
| Furuhata, K | 1 |
| Oonaka, K | 1 |
| Hara, T | 1 |
| Sunakawa, K | 1 |
| Dietz, M | 1 |
| Haas, M | 1 |
| Lindner, B | 1 |
| Dhople, AM | 1 |
| Tebebe, YB | 1 |
| Seydel, U | 1 |
6 other studies available for ofloxacin and Electrolytes
| Article | Year |
|---|---|
Gum ghatti-chitosan polyelectrolyte nanoparticles: preparation and characterization.
Topics: Anti-Bacterial Agents; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Electrolytes; Nanoparticl | 2013 |
Hyaluronic acid as an internal phase additive to obtain ofloxacin/PLGA microsphere by double emulsion method.
Topics: Adsorption; Anti-Bacterial Agents; Calibration; Drug Delivery Systems; Electrolytes; Emulsions; Hyal | 2014 |
Green preparation of antibiotic nanoparticle complex as potential anti-biofilm therapeutics via self-assembly amphiphile-polyelectrolyte complexation with dextran sulfate.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Calorimetry, Differential Scanning; Dextran | 2012 |
Chiral separation by capillary affinity zone electrophoresis using an albumin-containing support electrolyte.
Topics: Anti-Infective Agents; Buffers; Chromatography, Affinity; Electrochemistry; Electrolytes; Electropho | 1994 |
[Antibacterial activity of fosfomycin against the causative bacteria isolated from bacterial enteritis].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Blood; Campylobacter; Electrolyt | 2000 |
Intrabacterial sodium-to-potassium ratios and ATP contents of Mycobacterium leprae from ofloxacin-treated patients.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Biopsy; Electrolytes; Female; Humans; Leprosy; Male | 1991 |