ofloxacin has been researched along with Ear Infection in 3 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ofloxacin is a fluoroquinolone antibacterial with potent bactericidal activities and the topical otological preparation of this drug has been clinically utilised since the late 1980s." | 6.42 | A benefit-risk assessment of ofloxacin otic solution in ear infection. ( Tong, MC; Wai, TK, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wai, TK | 1 |
| Tong, MC | 1 |
| Oberascher, G | 1 |
| Karas, C | 1 |
1 review available for ofloxacin and Ear Infection
| Article | Year |
|---|---|
A benefit-risk assessment of ofloxacin otic solution in ear infection.
Topics: Administration, Topical; Anti-Infective Agents; Humans; Ofloxacin; Otitis; Risk Assessment | 2003 |
2 other studies available for ofloxacin and Ear Infection
| Article | Year |
|---|---|
Fluoroquinolones in ambulatory ENT and respiratory tract infections: rarely appropriate.
Topics: Ambulatory Care; Ciprofloxacin; Contraindications; Fluoroquinolones; Humans; Ofloxacin; Otitis; Resp | 2003 |
[Ofloxacin in the treatment of Pseudomonas aeruginosa infections of the ear].
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Ofloxacin; Otitis; Otitis Externa; Otitis Media; Oxa | 1988 |