ofloxacin has been researched along with ENT Diseases in 5 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ofloxacin was used at a dosage of 300 mg to 800 mg daily for three to 20 days in 206 cases of various infectious diseases in the otorhinolaryngological field such as otitis media, external otitis, paranasal sinusitis, tonsillitis and pharyngolaryngitis." | 2.66 | Clinical efficacy of ofloxacin in the treatment of otorhinolaryngological infections. ( Baba, S, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suzuki, K | 1 |
| Kurono, Y | 1 |
| Kobayashi, T | 1 |
| Nishimura, T | 1 |
| Baba, S | 2 |
| Harabuchi, Y | 1 |
| Fujisawa, T | 1 |
| Yamanaka, N | 1 |
| Ubukata, K | 1 |
| Ikeda, F | 1 |
| Matsuzaki, K | 1 |
| Watabe, E | 1 |
| Yoshimori, K | 1 |
| Shikano, M | 1 |
| Sato, Y | 1 |
| Hasegawa, M | 1 |
| Kobayashi, I | 1 |
| Tolsdorff, P | 1 |
| Poole, MD | 1 |
1 trial available for ofloxacin and ENT Diseases
| Article | Year |
|---|---|
Clinical efficacy of ofloxacin in the treatment of otorhinolaryngological infections.
Topics: Anti-Infective Agents; Bacterial Infections; Clinical Trials as Topic; Humans; Laryngitis; Ofloxacin | 1986 |
4 other studies available for ofloxacin and ENT Diseases
| Article | Year |
|---|---|
[Mutant prevention concentrations of garenoxacin against Streptococcus pneumoniae isolates from otorhinolaryngological infections].
Topics: Anti-Bacterial Agents; Aza Compounds; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; | 2010 |
[Antibacterial activity of gatifloxacin against various fresh clinical isolates in 2002].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Cefdinir; Cephalosporins; Ciprof | 2002 |
Concentrations of ofloxacin in ear and nasal tissues.
Topics: Administration, Oral; Adult; Cholesteatoma; Ear Cartilage; Ear, Middle; Female; Humans; Male; Middle | 1993 |
Limiting the use of the quinolones--ciprofloxacin and ofloxacin.
Topics: Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Humans; Oflo | 1992 |