ofloxacin has been researched along with Dysentery, Shiga bacillus in 11 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ofloxacin was used in the treatment of 20 cases of typhoid fever, 32 cases of bacillary dysentery and 50 cases of gonococcal infection." | 7.68 | [Clinical effect and laboratory observation of ofloxacin in the treatment of typhoid fever, bacillary dysentery and gonorrhea]. ( Jiang, YF; Wang, QN; Zou, QY, 1991) |
| "Ofloxacin was used in the treatment of 20 cases of typhoid fever, 32 cases of bacillary dysentery and 50 cases of gonococcal infection." | 3.68 | [Clinical effect and laboratory observation of ofloxacin in the treatment of typhoid fever, bacillary dysentery and gonorrhea]. ( Jiang, YF; Wang, QN; Zou, QY, 1991) |
| "Ofloxacin was superior by the efficacy to the other antibiotics." | 2.68 | [Treatment of Flexner's dysentery with ofloxacin]. ( Kulikov, VP; Rakhmanova, AG, 1996) |
| "In a word, both drugs are effective in treating bacterial infections of digestive system, urinary system and respiratory tract." | 2.67 | [Clinical efficacy of ciprofloxacin and ofloxacin]. ( Jiang, SC; Miao, JZ; Wang, XF, 1994) |
| "Shigellosis is a common cause of morbidity, especially in the very young and old, in developing countries." | 1.35 | Trends in antimicrobial resistance in Shigella species in Karachi, Pakistan. ( Ejaz, M; Jabeen, K; Khan, E; Shezad, MF; Siddiqui, J; Zafar, A, 2009) |
| "Treatment of levofloxacine 300 mg a day for 5 days successfully eliminated S." | 1.31 | [A Shigella sonnei outbreak in Nagasaki]. ( Hamamoto, A; Ishii, Y; Kinosita, K; Kohno, S; Suyama, N, 2000) |
| "Among them, 9 patients suffered from shigellosis (8 S." | 1.28 | [Treatment of salmonellosis and shigellosis with the new quinolones]. ( Biron, F; Boibieux, A; Peyramond, D; Tigaud, S, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, E | 1 |
| Jabeen, K | 1 |
| Ejaz, M | 1 |
| Siddiqui, J | 1 |
| Shezad, MF | 1 |
| Zafar, A | 1 |
| Saito, M | 1 |
| Seo, T | 1 |
| Matsubara, Y | 1 |
| Tomizawa, I | 1 |
| Takizawa, Y | 1 |
| Ito, K | 1 |
| Konishi, K | 1 |
| Matsunaga, M | 1 |
| Yanagishita, T | 1 |
| Kosugi, M | 1 |
| Jiang, SC | 1 |
| Wang, XF | 1 |
| Miao, JZ | 1 |
| Rakhmanova, AG | 1 |
| Kulikov, VP | 1 |
| Lobzin, IuV | 1 |
| Hamamoto, A | 1 |
| Kinosita, K | 1 |
| Suyama, N | 1 |
| Ishii, Y | 1 |
| Kohno, S | 1 |
| Zou, QY | 1 |
| Wang, QN | 1 |
| Jiang, YF | 1 |
| Biron, F | 1 |
| Boibieux, A | 1 |
| Tigaud, S | 1 |
| Peyramond, D | 1 |
| Lang, R | 1 |
| Lishner, M | 1 |
| Segev, S | 1 |
| Rubinstein, E | 1 |
| Korten, V | 1 |
| Mert, A | 1 |
| Ovünç, K | 1 |
| Ceyhan, M | 1 |
| Acar, S | 1 |
| Ulaş, T | 1 |
| Sen, D | 1 |
| Niyogi, SK | 1 |
| Ghosh, AR | 1 |
| Pal, SC | 1 |
1 review available for ofloxacin and Dysentery, Shiga bacillus
| Article | Year |
|---|---|
Ofloxacin and the gastrointestinal tract: a potential role in the treatment of bacterial enteritis.
Topics: Administration, Oral; Digestive System; Drug Administration Schedule; Dysentery, Bacillary; Feces; G | 1990 |
4 trials available for ofloxacin and Dysentery, Shiga bacillus
| Article | Year |
|---|---|
[Comparison of clinical efficacy of ofloxacin COFLX: DL-8280) and pipemidic acid (PPA) in acute infectious diarrhea by a double-blind method. The Japan Research Committee of Ofloxacin, Research Group for Acute Infectious Diarrhea].
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Campylobacter I | 1984 |
[Clinical efficacy of ciprofloxacin and ofloxacin].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Ciprofloxacin; Dysentery, Bacillary; Female; Gonorrhe | 1994 |
[Treatment of Flexner's dysentery with ofloxacin].
Topics: Aged; Anti-Infective Agents; Dysentery, Bacillary; Female; Humans; Male; Ofloxacin; Shigella flexner | 1996 |
[An attempt to use ofloxacin in the treatment of acute intestinal infections].
Topics: Acute Disease; Anti-Infective Agents; Chlamydia Infections; Drug Resistance, Microbial; Dysentery, B | 1996 |
6 other studies available for ofloxacin and Dysentery, Shiga bacillus
| Article | Year |
|---|---|
Trends in antimicrobial resistance in Shigella species in Karachi, Pakistan.
Topics: Adolescent; Adult; Age Factors; Ampicillin; Anti-Infective Agents; Ceftriaxone; Child; Child, Presch | 2009 |
[A Shigella sonnei outbreak in Nagasaki].
Topics: Anti-Infective Agents; Disease Outbreaks; Dysentery, Bacillary; Humans; Japan; Levofloxacin; Ofloxac | 2000 |
[Clinical effect and laboratory observation of ofloxacin in the treatment of typhoid fever, bacillary dysentery and gonorrhea].
Topics: Adult; Dysentery, Bacillary; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Ag | 1991 |
[Treatment of salmonellosis and shigellosis with the new quinolones].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Ciprofloxacin; Dysentery, Bacillary; Female; Huma | 1990 |
[Shigella serotypes and drug resistance patterns of strains isolated in Etimesgut, Turkey, in 1987].
Topics: Ampicillin Resistance; Anti-Bacterial Agents; Ceftriaxone; Chloramphenicol Resistance; Drug Resistan | 1988 |
Susceptibility of epidemic strains of Shigella to ofloxacin and other antimicrobials.
Topics: Anti-Bacterial Agents; Disease Outbreaks; Drug Resistance, Microbial; Dysentery, Bacillary; Humans; | 1988 |