ofloxacin has been researched along with Dry Eye Syndromes in 2 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Dry Eye Syndromes: Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Background and Objectives: A prospective, randomized clinical trial was conducted to evaluate the concentration of ofloxacin in the aqueous humour (AqH) of patients suffering from dry eye disease (DED) after topical instillation." | 9.51 | Aqueous Humour Ofloxacin Concentration after Topical Instillation in Patients with Dry Eye Disease. ( El Mubarak, MA; Georgakopoulos, CD; Kagkelaris, K; Panaretos, D; Panayiotakopoulos, GD; Plotas, P; Sivolapenko, GB, 2022) |
| "Background and Objectives: A prospective, randomized clinical trial was conducted to evaluate the concentration of ofloxacin in the aqueous humour (AqH) of patients suffering from dry eye disease (DED) after topical instillation." | 5.51 | Aqueous Humour Ofloxacin Concentration after Topical Instillation in Patients with Dry Eye Disease. ( El Mubarak, MA; Georgakopoulos, CD; Kagkelaris, K; Panaretos, D; Panayiotakopoulos, GD; Plotas, P; Sivolapenko, GB, 2022) |
| "The clinical features of the dry eye and ocular surface disease and management issues are discussed." | 1.35 | Management of evaporative dry eye in ectrodactyly-ectodermal dysplasia-clefting syndrome. ( Dogru, M; Endo, K; Goto, E; Matsumoto, Y; Ota, Y; Tsubota, K; Uchino, Y, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kagkelaris, K | 1 |
| El Mubarak, MA | 1 |
| Plotas, P | 1 |
| Panaretos, D | 1 |
| Panayiotakopoulos, GD | 1 |
| Sivolapenko, GB | 1 |
| Georgakopoulos, CD | 1 |
| Ota, Y | 1 |
| Matsumoto, Y | 1 |
| Dogru, M | 1 |
| Goto, E | 1 |
| Uchino, Y | 1 |
| Endo, K | 1 |
| Tsubota, K | 1 |
1 trial available for ofloxacin and Dry Eye Syndromes
| Article | Year |
|---|---|
Aqueous Humour Ofloxacin Concentration after Topical Instillation in Patients with Dry Eye Disease.
Topics: Administration, Topical; Anti-Infective Agents; Aqueous Humor; Dry Eye Syndromes; Humans; Ofloxacin; | 2022 |
1 other study available for ofloxacin and Dry Eye Syndromes
| Article | Year |
|---|---|
Management of evaporative dry eye in ectrodactyly-ectodermal dysplasia-clefting syndrome.
Topics: Adult; Corneal Diseases; Dry Eye Syndromes; Ectodermal Dysplasia; Eye Abnormalities; Foot Deformitie | 2008 |