ofloxacin has been researched along with Diabetic Neuropathies in 2 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Renal-dose levofloxacin was utilized as part of an antimicrobial regimen to treat post-operative peritonitis." | 3.74 | Levofloxacin-associated hypoglycaemia complicated by pontine myelinolysis and quadriplegia. ( Gregory, J; Huesmann, G; Jakoby, MG; Vallurupalli, S, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vallurupalli, S | 1 |
| Huesmann, G | 1 |
| Gregory, J | 1 |
| Jakoby, MG | 1 |
| Mueller-Buehl, U | 1 |
| Diehm, C | 1 |
| Gutzler, F | 1 |
| Adam, D | 1 |
1 trial available for ofloxacin and Diabetic Neuropathies
| Article | Year |
|---|---|
Tissue concentrations of ofloxacin in necrotic foot lesions of diabetic and non-diabetic patients with peripheral arterial occlusive disease.
Topics: Aged; Bacterial Infections; Diabetic Angiopathies; Diabetic Neuropathies; Female; Foot; Humans; Isch | 1991 |
1 other study available for ofloxacin and Diabetic Neuropathies
| Article | Year |
|---|---|
Levofloxacin-associated hypoglycaemia complicated by pontine myelinolysis and quadriplegia.
Topics: Anti-Bacterial Agents; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Hypoglycemia; Kidne | 2008 |