Page last updated: 2024-11-01

ofloxacin and Diabetes Mellitus, Type 1

ofloxacin has been researched along with Diabetes Mellitus, Type 1 in 6 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

Research Excerpts

ExcerptRelevanceReference
"A 72-year-old female dialysis patient with insulin-dependent diabetes mellitus who was under long-term medication with oral prednisolone due to chronic obstructive pulmonary disease was given levofloxacin for one week to treat an acute bronchitis (one 500 mg dose on the first day, 125 mg/day orally from second day onwards)."3.74[Fluoroquinolone-induced Achilles tendon rupture]. ( Maurin, N, 2008)
"Cellulitis is usually caused by organisms such as beta-hemolytic streptococci and Staphylococcus aureus."1.32Sepsis in a renal transplant recipient due to Citrobacter braakii. ( Agraharkar, ML; Gupta, R; Rauf, SJ; Singh, S; Smith, J, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gupta, R1
Rauf, SJ1
Singh, S1
Smith, J1
Agraharkar, ML1
Benbrika, S1
Boukari, L1
Stirnemann, J1
Letellier, E1
Fain, O1
Thomas, M1
Kettaneh, A1
Carranza González, R1
Tena Gómez, D1
Prieto Gómez, E1
Barberá Farré, JR1
Fernández Cenjor, J1
Maurin, N1
Brattström, C2
Malmborg, AS1
Tydén, G2
Malborg, AS1

Other Studies

6 other studies available for ofloxacin and Diabetes Mellitus, Type 1

ArticleYear
Sepsis in a renal transplant recipient due to Citrobacter braakii.
    Southern medical journal, 2003, Volume: 96, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Bacteremia; Cellulitis; Citrobacter freundi

2003
[A case of yersiniasis with multiple liver abscesses].
    La Revue de medecine interne, 2005, Volume: 26, Issue:2

    Topics: Diabetes Mellitus, Type 1; Drug Therapy, Combination; Hemochromatosis; Hepatitis; Humans; Imipenem;

2005
[Pneumonia by Corynebacterium pseudodiphteriticum: an infection to consider].
    Anales de medicina interna (Madrid, Spain : 1984), 2006, Volume: 23, Issue:3

    Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ceftriaxone; Corynebacte

2006
[Fluoroquinolone-induced Achilles tendon rupture].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:6

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Bronchitis; Diabetes Mellitus, Type 1; Female; Humans;

2008
Penetration of ciprofloxacin and ofloxacin into human allograft pancreatic juice.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 22, Issue:2

    Topics: Adult; Ciprofloxacin; Diabetes Mellitus, Type 1; Half-Life; Humans; Middle Aged; Ofloxacin; Pancreas

1988
Penetration of ciprofloxacin and ofloxacin into pancreatic juice.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Administration, Oral; Ciprofloxacin; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Humans; Kidn

1987