ofloxacin has been researched along with Dental Plaque in 3 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Dental Plaque: A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-five adult periodontitis patients with subgingival detection of Aa were treated with 2x200 mg/d ofloxacin for 5 days as adjunct to open flap surgery (test)." | 5.09 | Fluoroquinolones in the treatment of Actinobacillus actinomycetemcomitans-associated periodontitis. ( Kleinfelder, JW; Lange, DE; Mueller, RF, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kleinfelder, JW | 1 |
| Mueller, RF | 1 |
| Lange, DE | 1 |
| Mikx, FH | 1 |
| Langendijk, P | 1 |
| Renggli, HH | 1 |
| Kimura, S | 1 |
| Toda, H | 1 |
| Shimabukuro, Y | 1 |
| Kitamura, M | 1 |
| Fujimoto, N | 1 |
| Miki, Y | 1 |
| Okada, H | 1 |
2 trials available for ofloxacin and Dental Plaque
| Article | Year |
|---|---|
Fluoroquinolones in the treatment of Actinobacillus actinomycetemcomitans-associated periodontitis.
Topics: Actinobacillus Infections; Adult; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents; Colo | 2000 |
Topical chemotherapy in human periodontitis using a new controlled-release insert containing ofloxacin. I. Microbiological observation.
Topics: Administration, Topical; Adult; Analysis of Variance; Bacteria; Chronic Disease; Colony Count, Micro | 1991 |
1 other study available for ofloxacin and Dental Plaque
| Article | Year |
|---|---|
[Antibiotic use in periodontics. Results from a research study].
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria; Clindamycin; Dental Plaque; Doxycycline; Drug Resistan | 1996 |