ofloxacin has been researched along with Cystitis in 28 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.
Excerpt | Relevance | Reference |
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"To investigate the safety, efficacy and recurrence-inhibiting effect of a single dose of levofloxacin (LVFX) for the treatment of acute uncomplicated cystitis in women, 56 females with acute uncomplicated cystitis between 17 and 73 years old were studied, based on the urinary tract infection (UTI) drug efficacy evaluation." | 9.09 | [Efficacy of single-dose therapy with levofloxacin for acute cystitis: comparison to three-day therapy]. ( Amazutsumi, K; Harada, T; Kawamura, H; Koyama, Y; Matsuda, T; Mikami, O; Murota, T; Ohara, T; Uchida, J, 2000) |
"A comparative study of ofloxacin (OFLX), a new oral quinolone, was carried out at the Department of Urology, Osaka University Hospital and its eighteen affiliated hospitals to evaluate the clinical efficacy and safety of daily dose of 300 mg, given either once daily dose (SID group), or in three divided doses (TID group), in the treatment of acute uncomplicated cystitis in women." | 9.07 | [Clinical evaluation on ofloxacin administered once daily in the treatment of acute uncomplicated cystitis]. ( Fujioka, H; Kishimoto, T; Kokado, Y; Kuroda, H; Miki, T; Oda, M; Okuyama, A; Takatera, H; Yamada, R; Yasunaga, Y, 1994) |
"We compared the safety and efficacy of a single 400-mg dose of ofloxacin, ofloxacin (200 mg) once daily for 3 days, and trimethoprim-sulfamethoxazole (160:800 mg) twice daily for 7 days for the treatment of acute uncomplicated cystitis (urinary tract infection [UTI]) in women." | 9.07 | Single-dose and three-day regimens of ofloxacin versus trimethoprim-sulfamethoxazole for acute cystitis in women. ( Hooton, TM; Johnson, C; Kuwamura, L; Roberts, PL; Rogers, ME; Stamm, WE; Winter, C, 1991) |
"We compared the safety and efficacies of ofloxacin and trimethoprim-sulfamethoxazole for the treatment of acute uncomplicated cystitis in women enrolled in a multicenter study." | 9.06 | Ofloxacin versus trimethoprim-sulfamethoxazole for treatment of acute cystitis. ( Hooton, TM; Johnson, C; Latham, RH; Roberts, PL; Stamm, WE; Wong, ES, 1989) |
"Ofloxacin (OFLX) was administered to 236 female patients with acute cystitis." | 9.06 | [Clinical evaluation of ofloxacin in the treatment of acute cystitis]. ( Koyanagi, T; Kubota, M; Kumagai, A; Maru, A; Nantani, M; Sakakibara, N; Sakashita, S; Togashi, M; Tsubo, S; Yamazaki, H, 1987) |
"Fifty-three patients with urinary tract infections (UTI) were treated with Ofloxacin, a new oral synthetic antimicrobial agent, and its clinical efficacy was studied." | 7.67 | [Clinical study of ofloxacin (OFLX) on urinary tract infections]. ( Inada, F; Inagaki, N; Miyata, M; Mizunaga, M; Morikawa, M; Okamura, K; Osanai, H; Yachiku, S, 1987) |
" Among 33 patients given ofloxacin, the concentration of the drug in vaginal fluid during one dosage interval ranged from 1." | 6.66 | Pharmacodynamic evaluation of ofloxacin and trimethoprim-sulfamethoxazole in vaginal fluid of women treated for acute cystitis. ( Brust, P; Hooton, TM; Johnson, CR; Opheim, K; Stamm, WE; Tartaglione, TA, 1988) |
"Ofloxacin appears to be an appropriate antibiotic for short term therapy of acute, uncomplicated, lower urinary tract infections, comparing favourably with trimethoprim-sulphamethoxazole treatment in this study." | 6.66 | Ofloxacin versus trimethoprim-sulphamethoxazole in acute cystitis. ( Bjertnaes, A; Block, JM; Hafstad, PE; Holte, M; Ottemo, I; Peterson, LE; Rolstad, T; Svarva, PL; Walstad, RA, 1987) |
"To investigate the safety, efficacy and recurrence-inhibiting effect of a single dose of levofloxacin (LVFX) for the treatment of acute uncomplicated cystitis in women, 56 females with acute uncomplicated cystitis between 17 and 73 years old were studied, based on the urinary tract infection (UTI) drug efficacy evaluation." | 5.09 | [Efficacy of single-dose therapy with levofloxacin for acute cystitis: comparison to three-day therapy]. ( Amazutsumi, K; Harada, T; Kawamura, H; Koyama, Y; Matsuda, T; Mikami, O; Murota, T; Ohara, T; Uchida, J, 2000) |
"A 3-day regimen of trimethoprim-sulfamethoxazole is more effective and less expensive than 3-day regimens of nitrofurantoin, cefadroxil, or amoxicillin for treatment of uncomplicated cystitis in women." | 5.08 | Randomized comparative trial and cost analysis of 3-day antimicrobial regimens for treatment of acute cystitis in women. ( Hooton, TM; Stamm, WE; Tiu, F; Winter, C, 1995) |
"Fifteen patients with various forms of pyelonephritis and chronic cystitis were treated with ofloxacin." | 5.08 | [Comprehensive treatment with ofloxacin in pyo-inflammatory urologic diseases]. ( Pytel', IuA; Volkova, VS, 1996) |
"A comparative study of ofloxacin (OFLX), a new oral quinolone, was carried out at the Department of Urology, Osaka University Hospital and its eighteen affiliated hospitals to evaluate the clinical efficacy and safety of daily dose of 300 mg, given either once daily dose (SID group), or in three divided doses (TID group), in the treatment of acute uncomplicated cystitis in women." | 5.07 | [Clinical evaluation on ofloxacin administered once daily in the treatment of acute uncomplicated cystitis]. ( Fujioka, H; Kishimoto, T; Kokado, Y; Kuroda, H; Miki, T; Oda, M; Okuyama, A; Takatera, H; Yamada, R; Yasunaga, Y, 1994) |
"We compared the safety and efficacy of a single 400-mg dose of ofloxacin, ofloxacin (200 mg) once daily for 3 days, and trimethoprim-sulfamethoxazole (160:800 mg) twice daily for 7 days for the treatment of acute uncomplicated cystitis (urinary tract infection [UTI]) in women." | 5.07 | Single-dose and three-day regimens of ofloxacin versus trimethoprim-sulfamethoxazole for acute cystitis in women. ( Hooton, TM; Johnson, C; Kuwamura, L; Roberts, PL; Rogers, ME; Stamm, WE; Winter, C, 1991) |
"We compared the safety and efficacies of ofloxacin and trimethoprim-sulfamethoxazole for the treatment of acute uncomplicated cystitis in women enrolled in a multicenter study." | 5.06 | Ofloxacin versus trimethoprim-sulfamethoxazole for treatment of acute cystitis. ( Hooton, TM; Johnson, C; Latham, RH; Roberts, PL; Stamm, WE; Wong, ES, 1989) |
"Ofloxacin (OFLX) was administered to 236 female patients with acute cystitis." | 5.06 | [Clinical evaluation of ofloxacin in the treatment of acute cystitis]. ( Koyanagi, T; Kubota, M; Kumagai, A; Maru, A; Nantani, M; Sakakibara, N; Sakashita, S; Togashi, M; Tsubo, S; Yamazaki, H, 1987) |
" The following results were obtained in an investigation of the problems of complicated cystitis in vitro using ofloxacin." | 3.68 | [An in vitro study on the treatment of complicated cystitis using an automatic simulator]. ( Hirose, T; Kumamoto, Y; Nishimura, M; Ohya, S; Shibuya, A; Tsukamoto, T, 1990) |
"The effect of a single day treatment with 600 mg norfloxacin 600 mg ofloxacin or 1,920 mg trimethoprim-sulfamethoxazol was determined on 114 patients with acute cystitis." | 3.67 | [Single day treatment in acute cystitis]. ( Kawaguchi, K; Yamaguchi, K, 1988) |
"Fifty-three patients with urinary tract infections (UTI) were treated with Ofloxacin, a new oral synthetic antimicrobial agent, and its clinical efficacy was studied." | 3.67 | [Clinical study of ofloxacin (OFLX) on urinary tract infections]. ( Inada, F; Inagaki, N; Miyata, M; Mizunaga, M; Morikawa, M; Okamura, K; Osanai, H; Yachiku, S, 1987) |
"Ofloxacin, a new fluoroquinolone, was given to fifty patients (29 females and 21 males) aged 25 to 86 years with urinary tract infection or prostatitis." | 3.67 | [Ofloxacin (RU 43280): clinical evaluation in urinary and prostatic infections]. ( Acar, JF; Guibert, J, 1986) |
"Tosufloxacin was as effective as levofloxacin when administered twice daily for 2 days as prophylaxis for TBP, which suggests that this regimen is useful for reducing the clinical and febrile infection rate following TBP." | 2.73 | Antibiotic prophylaxis for transrectal prostate biopsy: a prospective randomized study of tosufloxacin versus levofloxacin. ( Ishitoya, S; Kamoto, T; Ogawa, O; Okumura, K; Segawa, T; Yamamoto, S, 2008) |
" Among 33 patients given ofloxacin, the concentration of the drug in vaginal fluid during one dosage interval ranged from 1." | 2.66 | Pharmacodynamic evaluation of ofloxacin and trimethoprim-sulfamethoxazole in vaginal fluid of women treated for acute cystitis. ( Brust, P; Hooton, TM; Johnson, CR; Opheim, K; Stamm, WE; Tartaglione, TA, 1988) |
"Ofloxacin appears to be an appropriate antibiotic for short term therapy of acute, uncomplicated, lower urinary tract infections, comparing favourably with trimethoprim-sulphamethoxazole treatment in this study." | 2.66 | Ofloxacin versus trimethoprim-sulphamethoxazole in acute cystitis. ( Bjertnaes, A; Block, JM; Hafstad, PE; Holte, M; Ottemo, I; Peterson, LE; Rolstad, T; Svarva, PL; Walstad, RA, 1987) |
" In practice, adverse events (AEs) of BCG therapy could restrict its prescription by urologists." | 2.48 | [Diagnosis and management of adverse events occuring during BCG therapy for non-muscle invasive bladder cancer (NMIBC): review of the Cancer Committee of the French Association of Urology]. ( Davin, JL; Irani, J; Larré, S; Moreau, JL; Neuzillet, Y; Pfister, C; Pignot, G; Rouprêt, M; Soulié, M; Wallerand, H, 2012) |
"Uncomplicated acute cystitis is one of the most common bacterial infections in adults." | 2.43 | Quinolones for uncomplicated acute cystitis in women. ( Andreeva, I; Rafalsky, V; Rjabkova, E, 2006) |
"Encrusted cystitis is a type of severe cystitis, which progresses chronically and is characterized by excessively alkaline urine and calcifications within the bladder wall." | 1.32 | [Two cases of encrusted cystitis]. ( Arai, Y; Ichioka, K; Matsui, Y; Ohara, H; Terada, N; Terai, A; Yoshimura, K, 2004) |
"We describe 7 Achilles tendinitis occurring during fluoroquinolone treatment." | 1.28 | Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy. ( Audisio, F; De Bandt, M; Hayem, G; Jorgensen, C; Kahn, MF; Meyer, O; Palazzo, E; Ribard, P, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (25.00) | 18.7374 |
1990's | 11 (39.29) | 18.2507 |
2000's | 7 (25.00) | 29.6817 |
2010's | 3 (10.71) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Mizuno, K | 1 |
Nakanishi, S | 1 |
Sakatani, T | 1 |
Kimura, R | 1 |
Asai, S | 1 |
Okazoe, H | 1 |
Toyosato, T | 1 |
Nishizawa, K | 1 |
Inoue, K | 1 |
Terai, A | 2 |
Kahan, NR | 1 |
Kahan, E | 1 |
Waitman, DA | 1 |
Kitai, E | 1 |
Chintz, DP | 1 |
Mirone, V | 1 |
Rubegni, P | 1 |
Feci, L | 1 |
Pellegrino, M | 1 |
Fimiani, M | 1 |
Neuzillet, Y | 1 |
Rouprêt, M | 1 |
Wallerand, H | 1 |
Pignot, G | 1 |
Larré, S | 1 |
Irani, J | 1 |
Davin, JL | 1 |
Moreau, JL | 1 |
Soulié, M | 1 |
Pfister, C | 1 |
Ohara, H | 1 |
Yoshimura, K | 1 |
Terada, N | 1 |
Ichioka, K | 1 |
Matsui, Y | 1 |
Arai, Y | 1 |
Rafalsky, V | 1 |
Andreeva, I | 1 |
Rjabkova, E | 1 |
Kosan, M | 1 |
Gonulalan, U | 1 |
Ozturk, B | 1 |
Kulacoglu, S | 1 |
Erguder, I | 1 |
Akdemir, O | 1 |
Cetinkaya, M | 1 |
Yamamoto, S | 1 |
Ishitoya, S | 1 |
Segawa, T | 1 |
Kamoto, T | 1 |
Okumura, K | 1 |
Ogawa, O | 1 |
Hooton, TM | 4 |
Winter, C | 2 |
Tiu, F | 1 |
Stamm, WE | 4 |
Okuyama, A | 1 |
Miki, T | 1 |
Kokado, Y | 1 |
Fujioka, H | 1 |
Kuroda, H | 1 |
Takatera, H | 1 |
Yasunaga, Y | 1 |
Kishimoto, T | 1 |
Yamada, R | 1 |
Oda, M | 1 |
Pytel', IuA | 1 |
Volkova, VS | 1 |
Nishimura, T | 1 |
Abe, H | 1 |
Ito, H | 1 |
Ikeda, K | 1 |
Oka, F | 1 |
Yamamoto, M | 1 |
Koyama, Y | 1 |
Mikami, O | 1 |
Matsuda, T | 1 |
Murota, T | 1 |
Ohara, T | 1 |
Kawamura, H | 1 |
Amazutsumi, K | 1 |
Uchida, J | 1 |
Harada, T | 1 |
Kumamoto, Y | 4 |
Nishimura, M | 3 |
Hirose, T | 3 |
Shibuya, A | 2 |
Tsukamoto, T | 3 |
Ohya, S | 2 |
Aoki, M | 1 |
Miyake, M | 1 |
Yanase, M | 1 |
Miyao, N | 1 |
Akagashi, K | 1 |
Yokoo, A | 1 |
Ribard, P | 1 |
Audisio, F | 1 |
Kahn, MF | 1 |
De Bandt, M | 1 |
Jorgensen, C | 1 |
Hayem, G | 1 |
Meyer, O | 1 |
Palazzo, E | 1 |
Johnson, C | 2 |
Kuwamura, L | 1 |
Rogers, ME | 1 |
Roberts, PL | 2 |
De Simone, C | 1 |
Di Fabio, S | 1 |
Moretti, S | 1 |
Tzantzoglou, S | 1 |
Trinchieri, V | 1 |
Gargiulo, M | 1 |
Latham, RH | 1 |
Wong, ES | 1 |
Yamaguchi, K | 1 |
Kawaguchi, K | 1 |
Tartaglione, TA | 1 |
Johnson, CR | 1 |
Brust, P | 1 |
Opheim, K | 1 |
Sakashita, S | 1 |
Kumagai, A | 1 |
Kubota, M | 1 |
Yamazaki, H | 1 |
Nantani, M | 1 |
Sakakibara, N | 1 |
Tsubo, S | 1 |
Togashi, M | 1 |
Maru, A | 1 |
Koyanagi, T | 1 |
Miyata, M | 1 |
Inagaki, N | 1 |
Inada, F | 1 |
Yachiku, S | 1 |
Okamura, K | 1 |
Osanai, H | 1 |
Mizunaga, M | 1 |
Morikawa, M | 1 |
Block, JM | 1 |
Walstad, RA | 1 |
Bjertnaes, A | 1 |
Hafstad, PE | 1 |
Holte, M | 1 |
Ottemo, I | 1 |
Svarva, PL | 1 |
Rolstad, T | 1 |
Peterson, LE | 1 |
Guibert, J | 1 |
Acar, JF | 1 |
3 reviews available for ofloxacin and Cystitis
Article | Year |
---|---|
[From cystitis to bacterial prostatitis: experience with levofloxacin].
Topics: Anti-Bacterial Agents; Bacterial Infections; Cystitis; Double-Blind Method; Drug Therapy, Combinatio | 2009 |
[Diagnosis and management of adverse events occuring during BCG therapy for non-muscle invasive bladder cancer (NMIBC): review of the Cancer Committee of the French Association of Urology].
Topics: Adjuvants, Immunologic; Administration, Intravesical; Anti-Infective Agents, Urinary; Arthralgia; BC | 2012 |
Quinolones for uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolo | 2006 |
14 trials available for ofloxacin and Cystitis
Article | Year |
---|---|
The tools of an evidence-based culture: implementing clinical-practice guidelines in an Israeli HMO.
Topics: Adult; Anti-Bacterial Agents; Clinical Competence; Cystitis; Evidence-Based Medicine; Female; Focus | 2009 |
Antibiotic prophylaxis for transrectal prostate biopsy: a prospective randomized study of tosufloxacin versus levofloxacin.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Biopsy; Cystitis; Fluoroq | 2008 |
Randomized comparative trial and cost analysis of 3-day antimicrobial regimens for treatment of acute cystitis in women.
Topics: Acute Disease; Adult; Amoxicillin; Anti-Infective Agents; Cefadroxil; Confidence Intervals; Costs an | 1995 |
[Clinical evaluation on ofloxacin administered once daily in the treatment of acute uncomplicated cystitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Cystitis; Drug Administration Schedule; Female; Humans; Japa | 1994 |
[Comprehensive treatment with ofloxacin in pyo-inflammatory urologic diseases].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Infective Agents, Urinary; Anti-Inflammatory | 1996 |
[Efficacy of single-dose therapy with levofloxacin for acute cystitis: comparison to three-day therapy].
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Child | 2000 |
Single-dose treatment of female acute uncomplicated cystitis.
Topics: Acute Disease; Administration, Oral; Anti-Infective Agents; Cefixime; Cefotaxime; Clinical Protocols | 1992 |
[Clinical efficacy of levofloxacin (LVFX) single-dose therapy in female acute uncomplicated cystitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Cystitis; Escherichia coli; Female; Humans; Levofloxacin; Mi | 1992 |
Single-dose and three-day regimens of ofloxacin versus trimethoprim-sulfamethoxazole for acute cystitis in women.
Topics: Acute Disease; Adult; Cystitis; Female; Humans; Ofloxacin; Perineum; Rectum; Trimethoprim, Sulfameth | 1991 |
Open randomized controlled parallel study of ofloxacin versus trimethoprim-sulfamethoxazole treatment of lower respiratory tract and urinary infections.
Topics: Acute Disease; Aged; Bronchitis; Bronchopneumonia; Chronic Disease; Cystitis; Escherichia coli; Fema | 1991 |
Ofloxacin versus trimethoprim-sulfamethoxazole for treatment of acute cystitis.
Topics: Acute Disease; Adult; Cystitis; Drug Resistance, Microbial; Feces; Female; Humans; Ofloxacin; Perine | 1989 |
Pharmacodynamic evaluation of ofloxacin and trimethoprim-sulfamethoxazole in vaginal fluid of women treated for acute cystitis.
Topics: Administration, Oral; Adult; Body Fluids; Cystitis; Drug Administration Schedule; Drug Combinations; | 1988 |
[Clinical evaluation of ofloxacin in the treatment of acute cystitis].
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Cystitis; Fe | 1987 |
Ofloxacin versus trimethoprim-sulphamethoxazole in acute cystitis.
Topics: Acute Disease; Anti-Infective Agents; Cystitis; Drug Combinations; Female; Humans; Infant, Newborn; | 1987 |
11 other studies available for ofloxacin and Cystitis
Article | Year |
---|---|
[A case of primary mucosa-associated lymphoid tissue-type lymphoma of the urinary bladder that progressed after antibiotic therapy].
Topics: Aged; Anti-Infective Agents, Urinary; Cystitis; Female; Humans; Lymphoma, B-Cell, Marginal Zone; Ofl | 2013 |
Photolocalized purpura during levofloxacin therapy.
Topics: Aged; Cystitis; Female; Humans; Levofloxacin; Ofloxacin; Purpura; Sunlight | 2012 |
[Two cases of encrusted cystitis].
Topics: Aged; Aged, 80 and over; Alkalosis; Anti-Infective Agents, Urinary; Calcium Carbonate; Carbonates; C | 2004 |
Tissue reactions of suture materials (polyglactine 910, chromed catgut and polydioxanone) on rat bladder wall and their role in bladder stone formation.
Topics: Animals; Anti-Infective Agents, Urinary; Catgut; Cystitis; Female; Foreign-Body Reaction; Mucous Mem | 2008 |
IL-1ra versus IL-1 levels in prostatic fluid from prostatitis patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Bacterial Infections; Body Fluids; C | 1998 |
[A clinical study on postantibiotic effect (PAE) and its application to chemotherapy for complicated cystitis with an automatic simulator of urinary drug concentration].
Topics: Amoxicillin; Anti-Infective Agents, Urinary; Automation; Cefixime; Cefotaxime; Cystitis; Enterobacte | 1992 |
Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy.
Topics: Achilles Tendon; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Cystitis; Female; Human | 1992 |
[An in vitro study on the treatment of complicated cystitis using an automatic simulator].
Topics: Computer Simulation; Cystitis; Escherichia coli; Humans; Models, Biological; Ofloxacin; Urine | 1990 |
[Single day treatment in acute cystitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Cystitis; | 1988 |
[Clinical study of ofloxacin (OFLX) on urinary tract infections].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Bacteria; | 1987 |
[Ofloxacin (RU 43280): clinical evaluation in urinary and prostatic infections].
Topics: Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cystitis; Female; Humans; Male; Middle Age | 1986 |