ofloxacin has been researched along with Crohn Disease in 2 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sweet's syndrome is an acute febrile neutrophilic dermatosis." | 1.33 | Ofloxacin induced Sweet's syndrome in a patient with Crohn's disease. ( Cakir, S; Kavak, A; Korkmaz, U; Küçükbayrak, A; Ozdemir, D; Sahin, I; Sencan, I, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tomás, ME | 1 |
| Pérez Carreras, M | 1 |
| Morillasa, JD | 1 |
| Castellano, G | 1 |
| Solís, JA | 1 |
| Ozdemir, D | 1 |
| Korkmaz, U | 1 |
| Sahin, I | 1 |
| Sencan, I | 1 |
| Kavak, A | 1 |
| Küçükbayrak, A | 1 |
| Cakir, S | 1 |
2 other studies available for ofloxacin and Crohn Disease
| Article | Year |
|---|---|
[Rupture of the Achilles' tendon secondary to levofloxacin].
Topics: Achilles Tendon; Adult; Ceftriaxone; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Humans | 2003 |
Ofloxacin induced Sweet's syndrome in a patient with Crohn's disease.
Topics: Adult; Anti-Bacterial Agents; Crohn Disease; Female; Humans; Ofloxacin; Skin; Sweet Syndrome | 2006 |