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ofloxacin and Conjunctivitis, Bacterial

ofloxacin has been researched along with Conjunctivitis, Bacterial in 19 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Conjunctivitis, Bacterial: Purulent infections of the conjunctiva by several species of gram-negative, gram-positive, or acid-fast organisms. Some of the more commonly found genera causing conjunctival infections are Haemophilus, Streptococcus, Neisseria, and Chlamydia.

Research Excerpts

ExcerptRelevanceReference
"3% levofloxacin eyedrops on the treatment of acute bacterial conjunctivitis and bacterial keratitis."9.09[Clinical investigation of 0.3% levofloxacin eyedrops on the treatment of cases with acute bacterial conjunctivitis and bacterial keratitis]. ( Chen, F; Hu, Y; Zhang, M, 2000)
" In this study we investigate the emergence of fluoroquinolone (ciprofloxacin, levofloxacin) resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis."7.72Ciprofloxacin and levofloxacin resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis. ( Alfonso, EC; Marangon, FB; Miller, D; Muallem, MS; Romano, AC, 2004)
"The aim of the study was to estimate changes in bacterial flora of conjunctival sac changes in patients prophylacticaly treated with different antibiotics (chloramphenicol, gentamycin, ofloxacin, norfloxacin) before cataract operation."5.11[Changes in bacterial flora of conjunctival sac in patients prophylacticaly treated with antibiotic before cataract operation]. ( Gerkowicz, M; Gruszecka-Gerkowicz, R; Kosior-Jarecka, E; Pietraś-Trzpiel, M, 2005)
"3% levofloxacin eyedrops on the treatment of acute bacterial conjunctivitis and bacterial keratitis."5.09[Clinical investigation of 0.3% levofloxacin eyedrops on the treatment of cases with acute bacterial conjunctivitis and bacterial keratitis]. ( Chen, F; Hu, Y; Zhang, M, 2000)
" In this study we investigate the emergence of fluoroquinolone (ciprofloxacin, levofloxacin) resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis."3.72Ciprofloxacin and levofloxacin resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis. ( Alfonso, EC; Marangon, FB; Miller, D; Muallem, MS; Romano, AC, 2004)
"The gatifloxacin eye drop has a good therapeutic effect to the bacterial conjunctivitis."2.75[Comparative research of the efficacy of the gatifloxacin and levofloxacin for bacterial conjunctivitis in human eyes]. ( Gong, L; Qiu, XD; Qu, J; Sun, XH; Xiong, QC; Yuan, ZL; Zhang, YQ, 2010)
"5% levofloxacin ophthalmic solution was found to be safe and effective in treating pediatric bacterial conjunctivitis."2.71Efficacy and safety of 0.5% levofloxacin ophthalmic solution for the treatment of bacterial conjunctivitis in pediatric patients. ( Lichtenstein, SJ; Rinehart, M, 2003)
"Ofloxacin was found as effective, safe, and comfortable as tobramycin in patients with external ocular infection and may provide earlier symptom relief."2.67Ofloxacin vs tobramycin for the treatment of external ocular infection. Ofloxacin Study Group II. ( Gwon, A, 1992)
"Gatifloxacin showed lower resistance levels than moxifloxacin."1.38[In vitro antibiotic susceptibility to fluoroquinolones]. ( Galvis, V; Rey, JJ; Tello, A; Villareal, D; Wong, CA, 2012)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (21.05)18.2507
2000's11 (57.89)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
D'Arienzo, PA1
Wagner, RS1
Jamison, T1
Bell, B1
Dajcs, JJ1
Stroman, DW1
Kodjikian, L1
Lafuma, A1
Khoshnood, B1
Laurendeau, C1
Berdeaux, G1
Gong, L1
Sun, XH1
Qiu, XD1
Zhang, YQ1
Qu, J1
Yuan, ZL1
Xiong, QC1
Wong, CA1
Galvis, V1
Tello, A1
Villareal, D1
Rey, JJ1
Nettis, E1
Giordano, D1
Pierluigi, T1
Ferrannini, A1
Tursi, A1
Zhang, M1
Hu, Y1
Chen, F1
Schwab, IR1
Friedlaender, M1
McCulley, J1
Lichtenstein, SJ2
Moran, CT1
Hwang, DG2
Schanzlin, DJ1
Rotberg, MH1
Foulks, G1
Raizman, MB1
Rinehart, M1
Marangon, FB1
Miller, D1
Muallem, MS1
Romano, AC1
Alfonso, EC1
Gerkowicz, M1
Gruszecka-Gerkowicz, R1
Kosior-Jarecka, E1
Pietraś-Trzpiel, M1
Qi, CX1
Wu, XM1
Wang, XL1
Zhang, W1
Wu, Y1
Zhao, J1
Lin, B1
Su, X1
Friedlaender, MH1
Snyder-Perlmutter, LS1
Katz, HR1
Melia, M1
Graves, A1
Henry, M1
O'Brien, TP1
Van Buskirk, A1
Trousdale, MD1
Wittpenn, JR1
Gwon, A1

Reviews

1 review available for ofloxacin and Conjunctivitis, Bacterial

ArticleYear
[Efficacy of moxifloxacin in treating bacterial conjunctivitis: a meta-analysis].
    Journal francais d'ophtalmologie, 2010, Volume: 33, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Conjunctivitis, Bacterial; Double-Blind

2010

Trials

12 trials available for ofloxacin and Conjunctivitis, Bacterial

ArticleYear
[Comparative research of the efficacy of the gatifloxacin and levofloxacin for bacterial conjunctivitis in human eyes].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2010, Volume: 46, Issue:6

    Topics: Adolescent; Adult; Conjunctivitis, Bacterial; Double-Blind Method; Female; Fluoroquinolones; Gatiflo

2010
[Clinical investigation of 0.3% levofloxacin eyedrops on the treatment of cases with acute bacterial conjunctivitis and bacterial keratitis].
    Yan ke xue bao = Eye science, 2000, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Conjunctivitis, Bacterial; Eye Infections, Bacterial

2000
A phase III clinical trial of 0.5% levofloxacin ophthalmic solution versus 0.3% ofloxacin ophthalmic solution for the treatment of bacterial conjunctivitis.
    Ophthalmology, 2003, Volume: 110, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteria; Child; Child, Preschool

2003
A phase III, placebo controlled clinical trial of 0.5% levofloxacin ophthalmic solution for the treatment of bacterial conjunctivitis.
    The British journal of ophthalmology, 2003, Volume: 87, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Child; Child, Preschool; Conjunct

2003
Efficacy and safety of 0.5% levofloxacin ophthalmic solution for the treatment of bacterial conjunctivitis in pediatric patients.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2003, Volume: 7, Issue:5

    Topics: Adolescent; Anti-Infective Agents; Child; Child, Preschool; Conjunctivitis, Bacterial; Dose-Response

2003
[Changes in bacterial flora of conjunctival sac in patients prophylacticaly treated with antibiotic before cataract operation].
    Klinika oczna, 2005, Volume: 107, Issue:10-12

    Topics: Antibiotic Prophylaxis; Cataract; Cataract Extraction; Chloramphenicol; Conjunctiva; Conjunctivitis,

2005
[Clinical research of isatis root eyedrops on the acute bacterial conjunctivitis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2007, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Conjunctivitis, Bacterial; Double-Blind Method; Drug

2007
Rapid diagnosis and treatment of chlamydial conjunctivitis.
    Chinese medical journal, 1995, Volume: 108, Issue:2

    Topics: Adolescent; Adult; Antigens, Bacterial; Child; Chlamydia trachomatis; Conjunctivitis, Bacterial; Enz

1995
[The clinical observation of China-made ofloxacin eye drops in the treatment of bacterial infection of the external eye].
    Yan ke xue bao = Eye science, 1994, Volume: 10, Issue:4

    Topics: Adult; Aged; Conjunctivitis, Bacterial; Hordeolum; Humans; Middle Aged; Ofloxacin; Ophthalmic Soluti

1994
Twice-a-day versus four-times-a-day ofloxacin treatment of external ocular infection.
    The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc, 1998, Volume: 24, Issue:1

    Topics: Administration, Topical; Anti-Infective Agents; Bacteria; Blepharitis; Colony Count, Microbial; Conj

1998
Effect of topical ciprofloxacin 0.3% and ofloxacin 0.3% on the reduction of bacterial flora on the human conjunctiva.
    Journal of cataract and refractive surgery, 2000, Volume: 26, Issue:11

    Topics: Alcaligenes; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Conjunctiva; Conjunctivi

2000
Ofloxacin vs tobramycin for the treatment of external ocular infection. Ofloxacin Study Group II.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1992, Volume: 110, Issue:9

    Topics: Blepharitis; Colony Count, Microbial; Conjunctiva; Conjunctivitis, Bacterial; Corneal Ulcer; Double-

1992

Other Studies

6 other studies available for ofloxacin and Conjunctivitis, Bacterial

ArticleYear
Comparison of fluoroquinolone kinetics of kill in susceptible and resistant gram-positive conjunctival pathogens.
    Advances in therapy, 2010, Volume: 27, Issue:1

    Topics: Anti-Bacterial Agents; Aza Compounds; Bacteriological Techniques; Ciprofloxacin; Conjunctivitis, Bac

2010
[In vitro antibiotic susceptibility to fluoroquinolones].
    Archivos de la Sociedad Espanola de Oftalmologia, 2012, Volume: 87, Issue:3

    Topics: Acanthamoeba Keratitis; Anti-Bacterial Agents; Aza Compounds; Body Fluids; Ciprofloxacin; Colombia;

2012
Erythema multiforme-like rash in a patient sensitive to ofloxacin.
    Acta dermato-venereologica, 2002, Volume: 82, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Conjunctivitis, Bacterial; Drug Hypersensitivity; Drug Therapy, Comb

2002
Ciprofloxacin and levofloxacin resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis.
    American journal of ophthalmology, 2004, Volume: 137, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; Conjunctivitis, Bacterial; Cross-Sectional Studies; Drug Resis

2004
In vitro susceptibilities of bacterial ocular isolates to fluoroquinolones.
    Cornea, 2001, Volume: 20, Issue:3

    Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Colony Count, Microbial; Conjunctivitis, Bacterial;

2001
Effect of ciprofloxacin and ofloxacin on bacterial flora.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:8

    Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Colony Count, Microbial; Conjunctiva; Conjunctivitis

2001