Page last updated: 2024-11-01

ofloxacin and Colitis

ofloxacin has been researched along with Colitis in 4 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johnson, LA1
Luke, A1
Sauder, K1
Moons, DS1
Horowitz, JC1
Higgins, PD1
Ohnishi, K1
Nakamura-Uchiyama, F1
Koga, H1
Aoyagi, K1
Yoshimura, R1
Kimura, Y1
Iida, M1
Fujishima, M1
Jüngst, G1
Mohr, R1

Trials

1 trial available for ofloxacin and Colitis

ArticleYear
Overview of postmarketing experience with ofloxacin in Germany.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 22 Suppl C

    Topics: Clinical Trials as Topic; Colitis; Drug Hypersensitivity; Drug Interactions; Female; Germany, West;

1988

Other Studies

3 other studies available for ofloxacin and Colitis

ArticleYear
Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: impact of a "Top-Down" approach to intestinal fibrosis in mice.
    Inflammatory bowel diseases, 2012, Volume: 18, Issue:3

    Topics: Actins; Analysis of Variance; Animals; Anti-Infective Agents; Cecum; Colitis; Colon; Cytokines; Fema

2012
Does levofloxacin induce hemolytic uremic syndrome in patients infected with verotoxin-producing Escherichia coli O157 infections?
    Japanese journal of infectious diseases, 2012, Volume: 65, Issue:5

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Colitis; Escherichia coli Infections; Escherichi

2012
Can quinolones cause hemorrhagic colitis of late onset? Report of three cases.
    Diseases of the colon and rectum, 1999, Volume: 42, Issue:11

    Topics: Acute Disease; Adult; Anti-Infective Agents; Bacterial Infections; Colitis; Colonoscopy; Enoxacin; F

1999